1,725,750 research outputs found
Pooled analysis of birth and later outcomes with individual prenatal care visit indicators (N = 7203).
No full textPooled analysis of birth and later outcomes with individual prenatal care visit indicators (N = 7203).</p
Associations of maternal prenatal care utilization index with offspring outcomes in four birth cohorts (n = 7203).
No full textAssociations of maternal prenatal care utilization index with offspring outcomes in four birth cohorts (n = 7203).</p
California Poll: 7203 -- May 30-31, 1972
No full textThe Field Poll, established in 1945 as The California Poll by Mervin Field, has operated continuously as an independent, non-partisan, media-sponsored public opinion news service. Each year the Field Polls cover a wide range of political and social topics examining California public opinion. Continuing measures are made of voter support for leading political figures vying for major state and federal offices, job ratings of important political figures and reactions to significant political events. Voter awareness, understanding and predispositions of major campaign issues and salient statewide ballot propositions are also tracked over time. For poll 7203 N=1603
Unique igneous textures and shock metamorphism of the Northwest Africa 7203 angrite:Implications for crystallization processes and the evolutionary history of the angrite parent body
No full textNorthwest Africa (NWA) 7203 is a quenched angrite, showing mineralogical features typically not present in other quenched angrites. NWA 7203 exhibits textures whose grain size varies from fine grains (<10 μm) to coarse grains (~3 mm), while other quenched angrites show only single-sized textures. Fine-grained and coarse-grained lithologies have nearly the same bulk compositions. Cooling rates were estimated to be ~80 °C h−1 for fine-grained lithologies and ~1 °C h−1 for coarse-grained lithologies. Mg-rich olivines (~Fo64) were found only in fine-grained lithologies. Crystallization of NWA 7203 started in the fine-grained lithologies with Mg-rich olivine grains acting as seeds for crystallization. Coarse-grained lithologies were subsequently formed under conditions of slower cooling. NWA 7203 shows clear shock metamorphic textures unlike other quenched angrites except for NWA 1670. We confirm that the oxygen isotopic ratios of NWA 7203 plot on the angrite fractionation line within uncertainty. However, the obtained Pb-Pb age of NWA 7203 is 4543 ± 19 Ma, younger than the ages of other quenched angrites, which might be a result of disturbance by shock metamorphism. The finding of shock metamorphism of NWA 7203 suggests that some angrites might be derived from asteroids that remained large (>10 km in diameter) during the late heavy bombardment.</p
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
EW-7203, a novel small molecule inhibitor of transforming growth factor-β (TGF-β) type I receptor/activin receptor-like kinase-5, blocks TGF-β1-mediated epithelial-to-mesenchymal transition in mammary epithelial cells
No full textRecently, small molecule inhibitors of transforming growth factorβ (TGF-β) type I receptor kinase/activin receptor-like kinase-5 (ALK5) have been developed to target TGF-β signalling as a therapeutic strategy for combating cancer. In the present study, the authors examined a novel small molecule inhibitor of ALK5, 3-((5-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-4-(6-methylpyridin-2-yl)thiazol-2-ylamino)methyl)benzonitrile (EW-7203) in breast cancer cells to determine if it has potential for cancer treatment. The inhibitory effects of EW-7203 on TGF-β-induced Smad signalling and epithelial-to-mesenchymal transition (EMT) were investigated in mammary epithelial cells using luciferase reporter assays, immunoblotting, confocal microscopy and wound healing assays. In addition, the suppressive effects of EW-7203 on mammary cancer metastasis to the lung were examined using a Balb/c xenograft model system. The novel ALK5 inhibitor, EW-7203, inhibited the TGF-β1-stimulated transcriptional activation of p3TP-Lux and pCAGA 12-Luc. In addition, EW-7203 decreased phosphorylated Smad2 levels and the nuclear translocation of Smad2 was increased by TGF-β1. In addition, EW-7203 inhibited TGF-β1-induced EMT and wound healing of NMuMG cells. Furthermore, in xenografted Balb/c mice, EW-7203 inhibited metastasis to the lung from breast tumors. The novel ALK5 inhibitor, EW-7203, efficiently inhibited TGF-β1-induced Smad signalling, EMT and breast tumor metastasis to the lung in vivo, demonstrating that EW-7203 has therapeutic potential for breast cancer metastasis to the lung. © 2011 Japanese Cancer Association
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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