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Secrett, R S, 7121
No full textThis record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete. Visit this record in UMA's new catalogue at: https://archives.library.unimelb.edu.au/nodes/view/416020Surname: SECRETT. Given Name(s) or Initials: R S. Military Service Number or Last Known Location: 7121. Missing, Wounded and Prisoner of War Enquiry Card Index Number: V-962.238173
Item: [2016.0049.48281] "Secrett, R S, 7121
Az UR-7121 jelű melléktermék égető kemence hatásfokának javítása
No full textA BorsodChem Zrt., TDI-II üzemében található UR-7121 jelű melléktermék égető kemencében végbemenő folyamatok modellezése. A gőzfejlesztő rendszer hatásfokainak és a gőztermelés növelésének vizsgálata.VegyészmérnökMSc/M
Enterocin AP-7121: combination with colistin against human multi-drug resistant Gram-negative pathogens: DOI: 10.5584/jiomics.v9i2.296
No full textThe significant prevalence of Gram-negative bacteria as health-care associated pathogens and their increased antimicrobial multi-drug resistance highlight the need for new therapeutic options. Colistin is a conventional antimicrobial currently employed for the treatment of nosocomial infections caused by multi-drug resistant Gram negative bacteria such as Pseudomonas aeruginosa and Acinetobacter baumannii complex with a main drawback, its toxicity. Doses of this drug, and its toxic effects, can be potentially reduced by using it combined with bacteriocins. AP-7121 is an enterocin produced by the probiotic strain Enterococcus faecalis CECT7121. The aim of this study was to investigate the synergistic activity of AP-7121 combined with colistin against multi-drug resistant Gram-negative pathogens. P. aeruginosa (n: 3) only susceptible to colistin and A. baumannii complex (n: 3) only susceptible to colistin and tigecycline were included. These human isolates were recovered from blood cultures (hemoculture) of patients with catheter-related bloodstream infections at the Intensive Care Unit (Hospital Ramon Santamarina de Tandil Argentina). Minimum Inhibitory Concentration (MIC) for AP, colistin, and colistin/AP-7121 combination against Gram-negative bacteria was assayed (micro-dilution method, CLSI 2018). In vitro bactericidal activity of AP alone or combined with colistin (MIC/4), for assessing a synergistic effect, was studied carrying out time-kill curves. Samples were obtained for viable cell counts (0, 4, 8 and 24 h). MIC and time-kill curves were carried out three times, in duplicate. Results were expressed as their average values. All isolates were resistant to AP (MICAP-7121 > 128 mg/L). Colistin showed anti-P. aeruginosa (MICcolistin 0.5 mg/L) and anti-A. baumannii complex (MICcolistin 0.5-1.0 mg/L) activity in each isolate. Colistin/AP-7121 Combination showed bactericidal activity against P. aeruginosa (MICcolistin/AP-7121 ≤ 0.06/11-0.12/16 mg/L) and A. baumannii (MICcolistin/AP-7121 ≤ 0.12-0.20/16 mg/L). A synergistic effect (colistin/AP-7121) was observed at 4-8 and 24 h for P. aeruginosa (-1.8 to -3.8 Δlog10 CFU/mL) and for A. baumannii complex isolates (-2.0 to -3.8 Δlog10 CFU/mL). AP-7121 is a candidate as an alternative option for the combination with colistin, against human P. aeruginosa and A. baumannii complex isolates producers of bloodstream infections. Their synergistic activity against these bacteria, leads to a bactericidal activity of AP, with lower MIC values and a potential reduction of colistin toxicity, to be thoroughly investigated
Effects of <i>Enterococcus faecalis</i> CECT 7121 on <i>Cryptosporidium parvum</i> infection in mice
No full textCryptosporidium is an opportunistic protozoan parasite of humans and animals worldwide and causes diarrheal disease that is typically self-limiting in immunocompetent hosts but often life threatening to immunocompromised individuals. However, there is a lack of completely efficient therapy available. Probiotics have attracted the attention as potential antiparasite compounds against protozoa involved in intestinal infections. This study investigated the effects of administration of probiotic Enterococcus faecalis CECT 7121 on Cryptosporidium parvum infection in immunosuppressed mice. Effects on C. parvum infection at the intestinal mucosa were studied and scored at each portion of the gut. It was demonstrated that Ef CECT 7121 interfered with C. parvum infection when both probiotic and parasite were present in the same intestinal location suggesting that Ef CECT 7121 supplementation can alleviate the negative effects of C. parvum infection.Facultad de Ciencias MédicasFacultad de Ciencias ExactasComisión de Investigaciones Científicas de la provincia de Buenos AiresCentro Universitario de Estudios Microbiológicos y Parasitológico
Effects of <i>Enterococcus faecalis</i> CECT 7121 on <i>Cryptosporidium parvum</i> infection in mice
No full textCryptosporidium is an opportunistic protozoan parasite of humans and animals worldwide and causes diarrheal disease that is typically self-limiting in immunocompetent hosts but often life threatening to immunocompromised individuals. However, there is a lack of completely efficient therapy available. Probiotics have attracted the attention as potential antiparasite compounds against protozoa involved in intestinal infections. This study investigated the effects of administration of probiotic Enterococcus faecalis CECT 7121 on Cryptosporidium parvum infection in immunosuppressed mice. Effects on C. parvum infection at the intestinal mucosa were studied and scored at each portion of the gut. It was demonstrated that Ef CECT 7121 interfered with C. parvum infection when both probiotic and parasite were present in the same intestinal location suggesting that Ef CECT 7121 supplementation can alleviate the negative effects of C. parvum infection.Facultad de Ciencias MédicasFacultad de Ciencias ExactasComisión de Investigaciones Científicas de la provincia de Buenos AiresCentro Universitario de Estudios Microbiológicos y Parasitológico
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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