1,727,708 research outputs found

    BM-5102: Organizational Behavior: Reflective Critique Report

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    This is a Reflective Critique Report on the experiences of the author while undergoing the BM-5102: Organizational Behavior module for Master of Management under UBD

    BM-5102 - 20M1304 REFLECTIVE REPORT

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    Organisational Behaviour (BM-5102) Reflective Report Assignmen

    Block Card 5102 Winona Drive

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    This image was produced by the Auditor's Office in Lucas County, Ohio for tax assessment purposes. Associated dates are approximate. Descriptive terms related to this photograph include: Ranch houses | 5102 Winona Road (Toledo, Ohio) | Dwelling | Elizabeth Park Addition (Toledo, Ohio) | Greenwood Park area (Toledo, Ohio

    Block Card 5102 Pawnee Road

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    This image was produced by the Auditor's Office in Lucas County, Ohio for tax assessment purposes. Associated dates are approximate. Descriptive terms related to this photograph include: Ranch houses | Dwelling | 5102 Pawnee Road (Toledo, Ohio) | Fairgreen Addition (Toledo, Ohio) | Trilby Area (Toledo, Ohio)) | West Toledo (Toledo, Ohio

    Parkinson's Patients with Dyskinesia Switched from Immediate Release Amantadine to Open‐label ADS‐5102

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    BackgroundADS-5102 (amantadine) extended release capsules (GOCOVRI™) are a treatment for dyskinesia in patients with Parkinson's disease (PD). ADS-5102 reduced dyskinesia and OFF time in phase 3 controlled trials of up to six months. Amantadine immediate release (IR) is used for dyskinesia, but suboptimal durability and tolerability limit its clinical utility.MethodsIn an ongoing, open-label, phase 3 study in the US and Western Europe (NCT02202551), patients with PD received 274 mg of ADS-5102 (equivalent to 340 mg amantadine HCl) once daily at bedtime for up to two years. Study outcomes included safety and assessment of motor complications, as measured by the Movement Disorder Society Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Part IV. This manuscript focuses on those patients switched to ADS-5102 from amantadine IR. Results in two groups of patients who previously completed a randomized controlled trial (EASE LID or EASE LID 3) are also presented according to use of ADS-5102 or placebo in that study before enrollment in the open-label study.ResultsChange in MDS-UPDRS Part IV at week 8 was -0.3 in the previous ADS-5102 subgroup (n = 61), -3.4 in the previous placebo subgroup (n = 79), and -3.4 in the previous amantadine IR subgroup (n = 32). Effects were maintained to week 64. In the previous amantadine IR subgroup (mean treatment duration, 2.5 years), mean amantadine IR dose was 221 mg. Safety data were consistent with previous randomized controlled trials of ADS-5102.ConclusionThese open-label data suggest ADS-5102 provides incremental reduction from baseline in MDS-UDPRS Part IV score in patients switched directly from amantadine IR, without exacerbating adverse events

    Block Card 5102 S. Willcrest Drive

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    This image was produced by the Auditor's Office in Lucas County, Ohio for tax assessment purposes. Associated dates are approximate. Descriptive terms related to this photograph include: Ranch houses | 5102 S. Willcrest Drive (Toledo, Ohio) | Dwelling | Westgate Extension (Toledo, Ohio) | South Toledo Area (Toledo, Ohio

    Block Card 5102 Valley Forge Drive

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    This image was produced by the Auditor's Office in Lucas County, Ohio for tax assessment purposes. Associated dates are approximate. Descriptive terms related to this photograph include: dwelling | 5102 Valley Forge Drive (Toledo, Ohio) | Cape Cod Style | Colonial Village | Greenwood Area (Toledo, Ohio) | West Toledo (Toledo, Ohio

    [Rock Island 5102 Train, Print #1]

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    Photograph of Rock Island Railway's 5102 train. The large, cylindrical locomotive is lined with horizontal pipes, a bell, and a circular light. The locomotive is sat on large wheels and holds a square cab at the back of it. Several train cars, some rectangular and some cylindrical, continue along the train's railroad to the right. A railroad runs along the foreground

    [Rock Island 5102 Train, Print #2]

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    Photograph of Rock Island Railway's 5102 locomotive. The cylindrical, pipe-covered locomotive sits on large wheels, a circular light and a bell at the front of it to the left. A square cab behind the locomotive, pulling rectangular and cylindrical train cars on the right. An overpass is visible above the train in the background

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    Contains fulltext : 5102.pdf (Publisher’s version ) (Open Access
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