1,723,822 research outputs found
Union Pacific (UP) 5088
No full textA photograph print showing Union Pacific (UP) 5088, 2-10-2, on westbound freight, Kansas City-Denver symbol Hotshot, F.O. Kelley posing, handing up to the caboose
Union Pacific (UP) 5088
No full textA photograph print showing Union Pacific (UP) 5088, 2-10-2, on westbound freight, Menoken, KS, F.O. Kelley posing, "handing 'em up to engineer"
Targeting miR-5088-5p attenuates radioresistance by suppressing Slug
No full textRadiotherapy is widely used for cancer treatment, but paradoxically, it has been reported that surviving cancer cells can acquire resistance, leading to recurrence or metastasis. Efforts to reduce radioresistance are required to increase the effectiveness of radiotherapy. miRNAs are advantageous as therapeutic agents because it can simultaneously inhibit the expression of several target mRNAs. Therefore, this study discovered miRNA that regulated radioresistance and elucidated its signaling mechanism. Our previous study confirmed that miR-5088-5p was associated with malignancy and metastasis in breast cancer. As a study to clarify the relationship between radiation and miR-5088-5p identified as onco-miRNA, it was confirmed that radiation induced hypomethylation of the promoter of miR-5088-5p and its expression increased. On the other hand, miR-5088-5p inhibitors were confirmed to reduce radiation-induced epithelial-mesenchymal transition, stemness, and metastasis by reducing Slug. Therefore, this study showed the potential of miR-5088-5p inhibitors as therapeutic agents to suppress radioresistance
Union Pacific (UP) 5088 & 4019
No full textA photograph postcard showing Union Pacific (UP) 5088, 2-10-2, and 4019, 4-8-8-4, west of Cheyenne, WY, on freight extra, 78 cars, 25 mph. (Note M.W. Swansick taking movies.
Odontogenic and nonodontogenic cysts in Istanbul: Analysis of 5088 cases
No full textBackground The aim of this study was to determine the prevalence of 5088 odontogenic and nonodontogenic cysts over a 40-year period in the Turkish population and to compare results with findings in the literature. Methods The records of odontogenic and nonodontogenic cysts, occurring during 1971 to 2010, were collected and analyzed for anatomic site, age range, and sex distribution. Results Among 5088 odontogenic and nonodontogenic cyst biopsies, 5003 cases (98.3%) were classified as odontogenic, whereas only 85 cases (1.7%) were nonodontogenic. In the former group, the most frequent diagnosis was radicular cyst (52.09%), followed by odontogenic keratocyst (20.6%) and dentigerous cyst (10.39%). Maxilla to mandible ratio was 1.13:1. The mean age of patients was 36.33 years (range, 287 years). The cysts were slightly more prevalent among male patients (57.70%). Conclusions The knowledge of the biological behavior and clinicopathologic features of jaw cysts constitute key aspects to provide early diagnosis and adequate surgery. (c) 2011 Wiley Periodicals, Inc. Head Neck, 201
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
- …
