1,726,031 research outputs found
New York Central (NYC) 4924
No full textA photograph print showing the New York Central (NYC) 4924, 4-6-2 (Class K-5B), St. Louis, MO
Produção de fitase por Aspergillus niger var. phoenicis URM 4924 utilizando planejamentos fatoriais
No full textOs fitatos representam uma classe complexa de compostos de ocorrência natural formados durante o processo de maturação de sementes e grãos de cereais, sendo a principal forma de armazenamento de fósforo em vegetais. A molécula de fitato é um grande fator anti-nutricional para monogástricos, possuindo em sua estrutura grupos ortofosfatos altamente ionizáveis, os quais afetam a disponibilidade de minerais no trato gastrointestinal. Fitases formam um grupo de enzimas com a capacidade de liberar o fósforo ligado à molécula do fitato, com a finalidade de aumentar o aproveitamento do fósforo para absorção. O objetivo deste trabalho foi avaliar parâmetros do meio de cultivo, tais como a concentração da fonte de nitrogênio e da fonte de carbono na produção de fitase por Aspergillus niger var. phoenicis URM 4924, utilizando planejamento fatorial. Para avaliar a influência de parâmetros do meio de cultivo na produção de fitase, realizou-se planejamento fatorial e metodologia de superfície de resposta. As melhores condições para a produção de fitase (8,80 U/mL) em fermentação submersa por A. niger var. phoenicis URM 4924 foram, 1,25% da fonte de carbono (farelo de arroz) e 3,0% da fonte de nitrogênio (milhocina). A. niger var. phoenicis URM 4924 apresentou potencial biotecnológico para produção de fitase que poderão ser adicionadas a alimentação de animais não-ruminantes, desta maneira, contribuindo para o aumento do aproveitamento de nutrientes e nos índices de produção
AKB-4924 attenuates urinary tract infection.
No full text<p>(<b>A</b>) Bladders isolated from female C57BL/6 mice infected with UPEC CFT073 for 6 h received localized treatment with 0.2 mg of AKB-4924 via transurethral injection for 16 h. Less bacteria were recovered from infected bladders treated with AKB-4924 compared to vehicle. Real-time qPCR shows elevated level of (<b>B</b>) murine AMP CRAMP and (<b>C</b>) mBD2 mRNA (n >11) in AKB-4924 treated animals. Error bar = S.E.M, **<i>P</i> < 0.01, *<i>P</i> < 0.05, Student’s unpaired two-tailed t-test. Results are compiled from 2 independent experiments.</p
Block Card 4924 Elm Place
No full textThis image was produced by the Auditor's Office in Lucas County, Ohio for tax assessment purposes. Associated dates are approximate. Descriptive terms related to this photograph include: Ranch houses | 4924 Elm Place (Toledo, Ohio) | Dwelling | Deveaux Area (Toledo, Ohio
Block Card 4924 Devonshire Road
No full textThis image was produced by the Auditor's Office in Lucas County, Ohio for tax assessment purposes. Associated dates are approximate. Descriptive terms related to this photograph include: Ranch houses | Dwelling | Southern Woods (Toledo, Ohio) | South Toledo Area (Toledo, Ohio) | 4924 Devonshire Road (Toledo, Ohio
Pretreatment with AKB-4924 impairs UPEC urinary tract colonization in C57BL/6 mice.
No full text<p>(<b>A</b>) Bladders from female C57BL/6 mice treated with 1 h vehicle, or 0.2 mg/mL AKB-4924, were recovered after 18–24 h UPEC CFT073 infection. Real-time qPCR shows increased Hif-1 mRNA in AKB-4924 treated animals. (<b>B</b>) Real-time qPCR and ELISA show increased VEGF mRNA and protein expression in AKB-4924 treated group. Data are generated from two independent repeats (n > 5 per experiment). (<b>C</b>) UPEC recoveries from urine (n = 15), bladder (n = 25) and both kidneys (n = 18) of mice that received 1 h of 4924 pre-treatment were significantly decreased compared to vehicle treated mice. Data is presented as mean +/- SEM, generated from 3–4 independent experiments, **<i>P</i> < 0.01. <i>Ex vivo</i> gentamicin protection assay revealed intracellular bacterial CFU from mice 18 h post-infection (n = 10,12)</p
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Reduced UPEC-mediated inflammatory damage to bladder epithelium with AKB-4924 pretreatment.
No full text<p>(<b>A, B</b>) ELISA analysis shows pro-inflammatory cytokines IL-6, IL-1β or KC in the bladders or kidneys are reduced in AKB-4924 treated mice 18–24 h post UPEC CFT073 infection. Results are compiled from more than two independent experiments (n > 3 per group). (<b>C</b>) Myeloperoxidase (MPO) assay of bladder supernatants (n = 9–11) indicates significant decrease in MPO activity in AKB-4924 pre-treated bladders 18h post UPEC CFT073 infection; Error bar = S.E.M *<i>P</i> < 0.05, Student’s two-tailed unpaired t-test. (<b>D</b>) Representative immunolocalization images of bladder MPO (red) and nuclei (DAPI, blue) of 18 h UTI89-infected mice with or without 4924 pre-treatment (n = 3–4 per group). Scale bar = 50 μm.</p
Linked collectors and determiners for: Amazoonops, a new genus of goblin spiders (Araneae: Oonopidae) from the Brazilian Amazon.
No full textNatural history specimen data linked to collectors and determiners held within, "Amazoonops, a new genus of goblin spiders (Araneae: Oonopidae) from the Brazilian Amazon". Claims or attributions were made on Bionomia by volunteer Scribes, <a href="http://bionomia.net/dataset/92b19f16-a3d8-4924-89ff-1800c1d048d0">https://bionomia.net/dataset/92b19f16-a3d8-4924-89ff-1800c1d048d0</a> using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, <a href="https://gbif.org/dataset/92b19f16-a3d8-4924-89ff-1800c1d048d0">https://gbif.org/dataset/92b19f16-a3d8-4924-89ff-1800c1d048d0</a>. Formatted as a Frictionless Data package
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