1,726,785 research outputs found
Morriss, George H, S-4332
This record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete. Visit this record in UMA's new catalogue at: https://archives.library.unimelb.edu.au/nodes/view/406316Surname: MORRISS. Given Name(s) or Initials: GEORGE H. Military Service Number or Last Known Location: S-4332. Missing, Wounded and Prisoner of War Enquiry Card Index Number: 9759.247453
Item: [2016.0049.38593] "Morriss, George H, S-4332
Block Card 4332 East Way
This image was produced by the Auditor's Office in Lucas County, Ohio for tax assessment purposes. Associated dates are approximate. Descriptive terms related to this photograph include: Dwelling (Toledo, Ohio) | Cape Cod Style | Homeville Subdivision (Toledo, Ohio) | Willys Park area (Toledo, Ohio) | West Toledo (Toledo, Ohio) | 4332 East Way (Toledo, Ohio
Block Card 4332 Imperial Drive
This image was produced by the Auditor's Office in Lucas County, Ohio for tax assessment purposes. Associated dates are approximate. Descriptive terms related to this photograph include: Ranch houses | Dwelling | Talmadge Gardens Addition (Toledo, Ohio) | Westgate Area (Toledo, Ohio) | 4332 Imperial Drive (Toledo, Ohio
Block Card 4332 Springbrook Drive
This image was produced by the Auditor's Office in Lucas County, Ohio for tax assessment purposes. Associated dates are approximate. Descriptive terms related to this photograph include: Ranch houses | Dwelling | Talmadge Gardens Addition (Toledo, Ohio) | Westgate Area (Toledo, Ohio) | 4332 Springbrook Drive (Toledo, Ohio
Block Card 4332 Rugby Drive
This image was produced by the Auditor's Office in Lucas County, Ohio for tax assessment purposes. Associated dates are approximate. Descriptive terms related to this photograph include: Cape Cod Style | Dwelling | Copland Woods Addition (Toledo, Ohio) | South Toledo Area (Toledo, Ohio) | 4332 Rugby Drive (Toledo, Ohio
Block Card 4332 Lyman Avenue
This image was produced by the Auditor's Office in Lucas County, Ohio for tax assessment purposes. Associated dates are approximate. Descriptive terms related to this photograph include: dwelling | 4332 Lyman Avenue (Toledo, Ohio) | Folk House Style | Craftsman Style | Walnut Hills Extension (Toledo, Ohio) | Willys Park area (Toledo, Ohio) | West Toledo (Toledo, Ohio
Block Card 4332 Kingsbury Avenue
This image was produced by the Auditor's Office in Lucas County, Ohio for tax assessment purposes. Associated dates are approximate. Descriptive terms related to this photograph include: dwelling | 4332 Kingsbury Avenue (Toledo, Ohio) | Tudor Cottage style | Elmwood Park (Toledo, Ohio) | Willys Park area (Toledo, Ohio) | West Toledo (Toledo, Ohio
Model-based interspecies scaling for predicting human pharmacokinetics of CB 4332, a complement factor I protein
Interspecies scaling of the pharmacokinetics (PK) of CB 4332, a 150 kDa recombinant complement factor I protein, was performed using traditional and model-based approaches to inform first-in-human dose selection. Plasma concentration versus time data from four preclinical PK studies of single intravenous and subcutaneous (SC) CB 4332 dosing in mice, rats and nonhuman primates (NHPs) were modeled simultaneously using naive pooling including allometric scaling. The human-equivalent dose was calculated using the preclinical no observed adverse effect level (NOAEL) as part of the dose-by-factor approach. Pharmacokinetic modeling of CB 4332 revealed species-specific differences in the elimination, which was accounted for by including an additional rat-specific clearance. Signs of anti-drug antibodies (ADA) formation in all rats and some NHPs were observed. Consequently, an additional ADA-induced clearance parameter was estimated including the time of onset. The traditional dose-by-factor approach calculated a maximum recommended starting SC dose of 0.9 mg/kg once weekly, which was predicted it to result in a trough steady-state concentration lower than the determined efficacy target range for CB 4332 in humans. Model simulations predicted the efficacy target range to be reached using 5 mg/kg once weekly SC dosing.Title in the list of papers of Rami Ayoun Alsoud's thesis: Model-based allometric scaling approaches for predicting human pharmacokinetics of CB 4332, a therapeutic complement factor I protein</p
Linked collectors and determiners for: Museu Paraense Emilio Goeldi - Araneae Collection.
Natural history specimen data linked to collectors and determiners held within, "Museu Paraense Emilio Goeldi - Araneae Collection". Claims or attributions were made on Bionomia by volunteer Scribes, <a href="http://bionomia.net/dataset/eb521f93-d62d-4332-a5f0-989ed94d9cc4">https://bionomia.net/dataset/eb521f93-d62d-4332-a5f0-989ed94d9cc4</a> using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, <a href="https://gbif.org/dataset/eb521f93-d62d-4332-a5f0-989ed94d9cc4">https://gbif.org/dataset/eb521f93-d62d-4332-a5f0-989ed94d9cc4</a>. Formatted as a Frictionless Data package
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