1,727,617 research outputs found

    Union Pacific (UP) 2891

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    A photograph print showing Union Pacific (UP) 2891, 4-6-2, on passenger train No. 4, Greeley, CO

    2891. Chronique de Flandre, ou Istore et chronique de Flandre

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    2891. Chronique de Flandre, ou Istore et chronique de Flandre. In: Molinier Auguste. Les Sources de l'histoire de France - Des origines aux guerres d'Italie (1494). III. Les Capétiens, 1180-1328. Paris : A. Picard et fils, 1903. p. 203

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    2891. Chronique de Flandre, ou Istore et chronique de Flandre

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    2891. Chronique de Flandre, ou Istore et chronique de Flandre. In: Molinier Auguste. Les Sources de l'histoire de France - Des origines aux guerres d'Italie (1494). III. Les Capétiens, 1180-1328. Paris : A. Picard et fils, 1903. p. 203

    Elmore, Donald Ray, b. 1938 (SC 2891)

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    Finding aid and full text of memoir (click on Additional Files below) for Mansucripts Small Collection 2891. Biographical memoir, well illustrated, of Donald R. Elmore, a Bowling Green, Kentucky native, describing his family, childhood, career in the U.S. Army, which included tours in Germany and Vietnam, and post-military life in California. A DVD contains images of Elmore’s drawings, craft work, military photographs, and miscellaneous biographical data on his jobs, travels, etc

    Three methods for 18F labeling of the HER2-binding Affibody molecule ZHER2:2891 including preclinical assessment

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    Human epidermal growth factor receptor (HER2)-targeted Affibody molecules radiolabeled with F-18 allow the noninvasive assessment of HER2 status in vivo through PET imaging. Such agents have the potential to improve patient management by selecting individuals for HER2-targeted therapies and allowing therapy monitoring. The aim of this study was to assess different F-18 radiolabeling strategies of the HER2-specific Affibody molecule Z(HER2:2891), preclinically determine the biologic efficacy of the different radiolabel molecules, and select a preferred radiolabeling strategy to progress for automated manufacture. Methods: Cysteine was added to the C terminus of the Affibody molecule for the coupling of maleimide linkers, and 3 radiolabeling strategies were assessed: silicon-fluoride acceptor approach (F-18-SiFA), F-18-AlF-NOTA, and 4-F-18-fluorobenzaldehyde (F-18-FBA). The biodistributions of the radiolabeled Affibody molecules were then determined in na ve CD-1 nude mice, and tumor targeting was assessed in CD-1 nude mice bearing high-HER2-expressing NCIN87 tumors and low-HER2-expressing A431 tumors. The 111InABY- 025 compound, which has demonstrable clinical utility, served as a reference tracer. Results: The non-decay-corrected radiochemical yields based on starting F-18-fluoride using the F-18-FBA, (18)FSiFA, and F-18-AlF-NOTA methods were 13% 6 3% (n = 5), 38% 6 2% (n = 3), and 11% 6 4% (n 5 6), respectively. In na ve mice, both the F-18-AlF-NOTA-Z(HER2:2891)and the 111In-ABY-025 compounds showed a significant kidney retention (70.3 +/- 1.3 and 73.8 +/- 3.0 percentage injected dose [% ID], respectively, at 90 min after injection), which was not observed for F-18-FBA-ZHER2: 2891 or F-18-SiFAZ(HER2:2891) (4.8 +/- 0.6 and 10.1 +/- 0.7 % ID, respectively, at 90 min). The F-18-SiFA-Z(HER2:2891) conjugate was compromised by increasing bone retention over time (5.3 6 1.0 % ID/g at 90 min after injection), indicating defluorination. All the radiolabeled Affibody molecules assessed showed significantly higher retention in NCI-N87 tumors than A431 tumors at all time points (P, 0.05), and PET/CT imaging of (18)FFBA-Z(HER2:2891) in a dual NCI-N87/A431 xenograft model demonstrated high tumor-to-background contrast for NCI-N87 tumors. Conclusion: The HER2 Affibody molecule Z(HER2:2891) has been site-selectively radiolabeled by three F-18 conjugation methods. Preliminary biologic data have identified F-18-FBA-Z(HER2:2891) (also known as GE226) as a favored candidate for further development and radiochemistry automation

    Linked collectors and determiners for: Type collections of Nepenthaceae at the Herbarium Bogoriense (BO), Indonesia.

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    Natural history specimen data linked to collectors and determiners held within, "Type collections of Nepenthaceae at the Herbarium Bogoriense (BO), Indonesia". Claims or attributions were made on Bionomia by volunteer Scribes, <a href="http://bionomia.net/dataset/7280afd1-2891-438e-9119-1798d4c8e99a">https://bionomia.net/dataset/7280afd1-2891-438e-9119-1798d4c8e99a</a> using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, <a href="https://gbif.org/dataset/7280afd1-2891-438e-9119-1798d4c8e99a">https://gbif.org/dataset/7280afd1-2891-438e-9119-1798d4c8e99a</a>. Formatted as a Frictionless Data package

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Windlast auf Hochhaeuser in Innenstadtbereichen - Messungen am Neubau des MAIN TOWER in Frankfurt/Main Abschlussbericht

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    SIGLEAvailable from TIB Hannover: RN 5905(2891) / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekDeutsches Inst. fuer Bautechnik (DIBt), Berlin (Germany)DEGerman
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