1,721,511 research outputs found
VPRS 6167 Registers Of Inwards Correspondence [Series reserialised - see VPRS 14332/P2 and VPRS 14336/P2]
No full textRegisters Of Inwards Correspondence [Series reserialised - see VPRS 14332/P2 and VPRS 14336/P2
Inhibition of dipeptidyl peptidase-4 (DPP4) activity in plasma and liver after injection of BI 14332.
No full text<p>BI 14332 was administered in a single dose of 3, 1 and 0.3 mg/kg body weight (BW) in dairy cows (n = 2/group). Plasma samples were taken 0.25, 0.5, 1, 2, 4, 6, 12, 24 and 48 h after the injection (<i>V</i>. <i>jugularis</i>; 3 mg/kg BW [□]; 1 mg/kg BW [Δ]; 0.3 mg/kg BW [○]). Liver samples were obtained by biopsy 4, 24 and 48 h after the injection (3 mg/kg BW [square]; 1 mg/kg BW [triangle]; 0.3 mg/kg BW [circle]). BI 14332 (x-axis) was shown to have a strong negative impact on DPP4 activity (y-axes), well approximated by a power function (represented as quasi linear model via log-log transformation) in liver: y = 7.72x<sup>-0.589</sup> (r<sup>2</sup> = 0.72) and plasma: y = 935.31x<sup>-0.081</sup> (r<sup>2</sup> = 0.76).</p
Effects of dipeptidyl peptidase IV inhibition via BI 14332 to dry matter intake (DMI) and milk yield of cows with subclinical ketosis (LSmeans ± SE).
No full text<p><sup>a</sup>With first occurrence of serum β-hydroxybutyrate (BHB) concentration ≥ 1.2 mM cows were treated with BI 14332 (HC-BI) or stayed untreated as control group (HC-Con). BI 14332 was applied once a day over a period of 7 days (intravenous, 0.3 mg/kg body weight). Subclinical ketosis was diagnosed during 1st and 2nd week of lactation (day +3, day +7 or day +10 after calving).</p><p><sup>b</sup>The first week (mean ± SD) was set as covariate, integrated in the MIXED procedure of SAS [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0136078#pone.0136078.ref024" target="_blank">24</a>] with group and time as fixed factors (P ≤0.05; Tukey test).</p><p>Effects of dipeptidyl peptidase IV inhibition via BI 14332 to dry matter intake (DMI) and milk yield of cows with subclinical ketosis (LSmeans ± SE).</p
Effects of dipeptidyl peptidase IV (DPP4) inhibition via BI 14332 to relative numbers of CD4<sup>+</sup> and CD8<sup>+</sup> T-lymphocytes (LSmean ± SE).
No full text<p><sup>a</sup>With first occurrence of serum β-hydroxybutyrate ≥ 1.2 mM cows were treated with BI 14332 (HC-BI) or stayed untreated as control group (HC-Con). BI 14332 was applied once a day over a period of 7 days (0.3 mg/kg body weight). Subclinical ketosis was diagnosed on day +3 (1 cow), day +7 (8 cows) or on day +10 (3 cows) after calving. Significant values (P ≤ 0.05) and trends (P ≤ 0.1) are shown in bold. LSmeans with different superscripts (a-b) within the same group are significantly different.</p><p>Effects of dipeptidyl peptidase IV (DPP4) inhibition via BI 14332 to relative numbers of CD4<sup>+</sup> and CD8<sup>+</sup> T-lymphocytes (LSmean ± SE).</p
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Inhibition of plasma and liver dipeptidyl peptidase-4 (DPP4) activities after injection of BI 14332.
No full text<p>BI 14332 was administered in a single dose of 3 [square], 1 [triangle] and 0.3 [circle] mg/kg body weight in dairy cows (n = 2/group). Plasma samples (<i>V</i>. <i>jugularis</i>) were taken 24 h before and immediately before (time zero “0”) injection, as well as 0.25, 0.5, 1, 2, 4, 6, 12, 24 and 48 h post injection (upper shape). Liver was biopsied 24 h before injection, as well as 4, 24 and 48 h thereafter (lower shape).</p
- …
