1,721,569 research outputs found

    Pin-bearing strengths for bolted connections in fibre-reinforced polymer structures

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    Presented in this paper are pin-bearing strengths for pultruded fibre-reinforced polymer materials that are required in order to check the bearing resistance when designing bolted connections. For steel pin diameters up to 16 mm, equivalent test results, at room temperature, using the European standard test method BS EN 13706-2 and another test method (such as ASTM D 5764) are shown not to be significantly different. As the latter method uses much smaller specimen blanks, new pin-bearing strengths can be determined for the web material in a 203 x 203 x 9.5 mm wide flange shape, with the connection force at 0 degrees, 45 degrees or 90 degrees to the direction of pultrusion. An evaluation is made of the test results and recommendations are given on how pin-bearing strengths are to be determined so that they will match the geometries of bolted connections and connection forces found in practice

    Structure of the Palaeozoic basement in the Coast of Chile at 31º 30’S latitude (Huentelauquén, Chile)

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    Congreso geológico de España (8º. 2012. Oviedo). Simposio Geología de la Cordillera de los Andes y su antepaísEste trabajo ha sido financiado por el Proyecto CGL2009-13706-CO3 (Plan I+D+i

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Escherichia coli (ATCC 13706) is susceptible to retapamulin, an antimicrobial semisynthetic derivative of pleuromutilin

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    Antimicrobial resistance (AMR) is a top 10 global threat to human health, as well as a major global health threat to animals and the environment. AMR can reduce the efficacy of antibiotic therapeutics, making treatment of bacterial infections difficult, expensive, and sometimes impossible. The increasing and wide-spread use of antibiotics has led to their global-scale misuse and abuse, resulting in the exponential emergence of antibiotic-resistant bacterial strains at alarming rates. The lack of speed in the development of new therapeutics for resistant bacteria is also a contributing factor to this global issue. Pleuromutilin, a diterpene natural product first isolated from the fungus Clitopilus passeckerianus, has been shown to be a potent inhibitor of Gram-positive (Staphylococcus aureus) and some Gram-negative bacteria (Haemophilus influenzae) by electively inhibiting bacterial translation. Retapamulin, the first drug in the new class of pleuromutilin antibiotics to be approved for human use as a topical antibiotic, was effective against Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) in clinical trials. Although most strains of the Gram-negative bacteria Escherichia coli (E. coli) are harmless, several strains have developed antibiotic resistance. E. coli (ATCC 13706) is commonly found in wastewater, therefore susceptible to becoming antibiotic resistant. Given the observed inhibitory effects of retapamulin and pleuromutilin against Gram-positive bacteria and some Gram-negative bacteria, respectively, we hypothesize that retapamulin hinders the growth of E. coli (ATCC 13706). After performing the Kirby Bauer disk diffusion assay, we found that retapamulin inhibits E. coli at 500 ug/ml and it plateaus at 2500 ug/ml (ANOVA, df (9,20), F=121.3, p=1.8x10exp-15). We will also assess the minimum inhibitory and bactericidal concentrations. Thus far, our study suggests that E. coli ATCC 13706 is susceptible to retapamulin

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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