1,817,423 research outputs found
Understanding global patterns of structural variation in Arabidopsis thaliana: Future of the 1001 Genome project
No full textThe recently released map of polymorphism of 1,135 re-sequenced A. thaliana natural inbred lines provides an invaluable resource to understand global genetic patterns in a large collection of wild individuals that are products of natural selection under diverse ecological conditions. Our work clarified prior hypotheses such as the strong impact of the last ice age on population structure and in addition revealed that modern A. thaliana is a mixture of stationary relicts and fast expanding survivors from different glacial refugia. In the future the resource will enable researchers to decipher more accurately how genetic variation translates into phenotypic variation. However, connecting hits from genome-wide association studies (GWAS) to causal sequences is still challenging since previous analysis approaches mostly rely on mapping to a single reference, which insufficiently captures structural variations (SVs) or the presence of sequences not found in the reference. Discovery and genotyping of such sequences remains computationally difficult with short read data, since they are often in repetitive regions and because they can the changes can be complex. The next objective for the 1001 Genomes project is to discover and genotype major classes of SVs in the global set of A. thaliana accessions. By reanalyzing the 1001 Genomes Project whole-genome sequencing (WGS) data together with long-read DNA technologies, we will survey SV mutation hotspots throughout the worldwide population and target so far undescribed patterns and classes of SV complexity. Here we present strategies, pilot studies and first results of our upcoming work that will provide structural variations and polymorphisms as an integrated resource alongside with detailed information about epigenomes as well as molecular and nonmolecular phenotypes to understand how traits are connected to genomes and epigenomes
1001 Ways to Relax
No full textFeeling stressed and want to learn how to relax? Here are 1001 easy-to-follow ways to unwind.
Follow bite-sized advice on kicking back and relaxing: pick up simple ideas for managing anger and keeping calm, massage techniques and yoga poses to help you de-stress and tips to cope with work and other stressful situations that would normally have you tearing your hair out. Plus find 100% natural recipes for relaxing, including bath oils and herbal teas.
No drugs or expensive therapy required: cope with your packed schedule, feel great and survive life in a busy world
Book Review: 1001 activities in environmental education
Get PDFBook Title: 1001 activities in environmental education (1997)Book Author: Nico AllersPublisher: Kamel eon Publishers, Vereenigin
Book Review: 1001 activities in environmental education
Get PDFBook Title. 1001 activities in environmental educa-tion (1997). Book Author. Nico Allers. Publisher. Kamel eon Publishers, Vereenigin
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Chitinozoan ocurrences in the TCB X-1001-Tacobo borehole.
No full textThe black circles represent positively identified species and the blue circle open nomenclature species. The gray circles are species restricted to the TCB X-1001-Tacobo borehole. The first group of species have their first record in Western Gondwana. The second group are species recorded in all the palaeocontinents, and the last group represents species restricted to Western Gonwana.</p
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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