1,720,966 research outputs found
The influence of apolipoprotein E polymorphism on lipoprotein metabolism in patients with chronic renal diseases
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Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Effects of increased body weight and short term weight loss on serum PCSK9 levels
No full textΕΙΣΑΓΩΓΗ-ΣΚΟΠΟΣ: Η proprotein convertase subtilisin/kexin type 9 (PCSK9) εμπλέκεται στον καταβολισμό των χαμηλής πυκνότητας λιποπρωτεϊνών (LDL). Σκοπός της μελέτης ήταν ο προσδιορισμός της συγκέντρωσης της PCSK9 στον ορό σε παχύσαρκους ασθενείς και η εκτίμηση της επίδρασης μιας βραχυπρόθεσμης απώλειας σωματικού βάρους.
ΥΛΙΚΟ ΚΑΙ ΜΕΘΟΔΟΙ: Παχύσαρκοι ασθενείς [δείκτης μάζας σώματος (BMI) >30 kg/m2] χωρίς ιστορικό καρδιαγγειακής νόσου ή λήψη φαρμάκων (n=35, ηλικία 4311 y) και υγιή άτομα φυσιολογικού σωματικού βάρους (n=20, ηλικία 356 y, ΒΜΙ<25 kg/m2) συμμετείχαν στη μελέτη. Σε ένα τυχαία επιλεγμένο δείγμα από την ομάδα των παχύσαρκων ασθενών (n=15) δόθηκε υποθερμιδική δίαιτα για 3 μήνες. Η PCSK9 στον ορό προσδιορίσθηκε με ενζυμική μέθοδο ανοσοπροσδιορισμού.ΑΠΟΤΕΛΕΣΜΑΤΑ: Οι παχύσαρκοι ασθενείς είχαν μεγαλύτερη ηλικία και είχαν σημαντικά υψηλότερα επίπεδα σωματικού βάρους, ΒΜΙ, ολικής χοληστερόλης, LDL χοληστερόλης, τριγλυκεριδίων, απολιποπρωτεΐνης Β και δείκτη ομοιοστασίας των υδατανθράκων ΗΟΜΑ, καθώς και χαμηλότερα επίπεδα χοληστερόλης των υψηλής πυκνότητας λιποπρωτεϊνών (HDL) σε σύγκριση με τα άτομα φυσιολογικού σωματικού βάρους (όλα p<0.05). Τα επίπεδα της PCSK9 ήταν σημαντικά υψηλότερα στα παχύσαρκα άτομα σε σύγκριση με τα άτομα φυσιολογικού σωματικού βάρους (229-65 έναντι 156-43 ng/mL, αντίστοιχα, p<0.01), ακόμη και μετά από προσαρμογή των αποτελεσμάτων ως προς την ηλικία και τα επίπεδα της απολιποπρωτεΐνης Β και του δείκτη ΗΟΜΑ. Η υποθερμιδική δίαιτα για 3 μήνες προκάλεσε σημαντική μείωση του σωματικού βάρους, των τριγλυκεριδίων και του δείκτη ΗΟΜΑ, χωρίς ωστόσονα συσχετισθεί με σημαντική μεταβολή των επιπέδων της PCSK9 στον ορό.
ΣΥΜΠΕΡΑΣΜΑΤΑ: Η PCSK9 στον ορό είναι αυξημένη σε παχύσαρκους ασθενείς σε σύγκριση με άτομα φυσιολογικού σωματικού βάρους. Η βραχυπρόθεσμη απώλεια σωματικού βάρους δεν επηρεάζει σημαντικά τα επίπεδα της PCSK9 στον ορό.Background: Proprotein convertase subtilisin/kexin type 9 (PCSK9)is associated with low-density lipoproteins (LDL) catabolism but its serum concentration is not uniformly associated with cardiovascular disease in clinical studies.Obesity is linked with increased cardiovascular risk.
Aim and Methods: Aim of this pilot study was to assess possible differences in plasma PCSK9 levels (determined with aquantitative sandwich enzyme immunoassay) between otherwise healthy drug-naïve obese subjects (n= 35, age 4311y) and healthy individuals with normal body weight (n=20, age 356y). Additionally, PCSK9 levels were
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determined at baseline and after a 3-month weight-loss program in a randomly assigned subgroup of the obese subjects (n=15).
Results: Obese subjects were older and had significantly increased body mass index (BMI), waist circumference, total cholesterol, triglycerides, LDL cholesterol (LDL-C), apolipoprotein B and homeostasis model assessment of insulin resistance (HOMA) index levels, as well assignificantly decreased high-density lipoprotein cholesterol(HDL-C) concentration, compared with normal-weight subjects. Plasma PCSK9 levels were significantly increased in obese subjects compared with normal-weight individuals, even after adjustment for age, LDL-C, triglycerides, HDL-C, apolipoprotein A1, apolipoprotein B, apolipoprotein E, glucose, insulin and HOMA index levels (p=0.018). Obese subjects experienced a significant weight loss (from 10922to 10423kg, p<0.01) after the 3-month diet, which was associated with improvement in triglycerideand apolipoprotein E levels. Plasma PCSK9 levels did not significantly change after the 3-month weight-loss program.
Conclusions: Plasma PCSK9 levels are increased in obese subjects compared with normal-weight individuals. Short-term weight loss does not change significantly plasma PCSK9 levels.81 σ
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
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