1,721,078 research outputs found
The influence of patients' education on quality of life, exercise capacity and clinical conditition in chronic heart failure.
No full textAim of the work: to evaluate influence of education on quality of life, exercise capacity and clinical status in patients suffering from chronic heart failure. Tasks of the work: to create educational heart failure programme for the patients. To evaluate the influence of education on changes of quality of life in patients suffering from chronic heart failure. To evaluate the influence of education on changes of B-type natriuretic peptide levels (functional status) in patients suffering from chronic heart failure. Study population: Patients suffering from chronic heart failure in stabile condition (functional NYHA class II – III), consulted at Vilnius University Santariškių Clinic Out – patient Department of Cardiology who had been receiving optimal treatment. Methods: The following data were evaluated before tuition and 2 months thereafter: 1. Quality of life (QoL) in accordance with standardized Minnesota questionnaire “Life With Heart Failure” (generali [QoLEI], physical, reflecting emotional QoLEI aspects). 2. Exercise capacity by means of spiroergometry: VO2peak ml/kg/min, VO2peak l/min, AT VO2 ml/kg/min, AT VO2 ml/kg/min, AT VO2 l/min and percentage value of this parameters workload (W), exercise duration in minutes, MET, NYHA, heart rate during anaerobic threshold, peak heart rate, VE/CO2, VE/VO2. Workload intensity was expressed in MET in order to determine NYHA functional class more objectively. 3. Clinical condition in accordance with B-type natriuretic peptide blood level. The date were processed using SPSS 13.0 software version for Windows. The level of significance was fixed and considered to be equal to 0.05; two sided p values were presented in all cases. Results: 1. The mean index of evaluation of quality of life (QoLEI) was 49.39 + 17.86 prior the tuition. Mean QoLEI of physical and emotional aspects were 21.7 + 7.15 and 9.35 + 5.48, respectively. QoLEI decreased up to 37.9 + 18.78 (p < 0.001); QoL corresponding physical and emotional aspects had decreased to17.74 + 7.09 (p < 0.001) and 7.74 + 5.31 (p < 0.001), respectively. 2. Peak VO2 ml/kg/min 2 months after tuition had significantly increased (16.25 + 3.69 vs. 19.26 + 7.22; p = 0.013). The positive changes in AT VO2 ml/kg/min were demonstrated 2 months after the tuition (11.197 + 2.47 vs. 12.694 + 3.28; p = 0.003). The indices reflecting external load had increased significantly: workload (W) 19.26 + 37.10 vs. 104.29 + 40.03; p = 0.001; duration of the exercise 7.28 + 2.59 vs. 8.32 + 2.95; p = 0.007; MET 4.65 + 1.05 vs. 5.20 + 1.27; p = 0.001). The ratio of patients in various NYHA functional classes prior the tuition and 2 months thereafter had also changed: NYHA I – 0/1; NYHA II – 10/19; NYHA III – 21/11. 3. The investigation demonstrated that the blood level of B-type natriuretic peptide (the index of clinical condition) had decreased significantly 2 months after the tuition (348.41 + 471.99 vs. 224 + 340.36; p = 0.023). Conclusions: The quality of life of the patients had improved significantly after the tuition. The tuition has reliable positive influence on exercise capacity. The oxygen volume taken from inspired air during peak exercise had increased significantly as well as oxygen volume taken from inspired air during anaerobic threshold, workload, duration of the exercise, metabolic oxygen consumption units. The heart rate during peak exercise, heart rate during anaerobic threshold and respiratory carbon dioxide coefficient had underwent positive changes. There is a positive relationship between tuition and functional NYHA class. The education had improved clinical condition of the patients suffering from heart failure. The blood levels of natriuretic peptide had decreased significantly after the tuition
Miokardo smūginės bangos terapijos veiksmingumas asmenims, sergantiems stabilia krūtinės angina: atsitiktinių imčių, trigubai aklas, imitacinės procedūros kontroliuojamas tyrimas.
No full textCoronary artery disease (CAD) is recognized to be a leading reason of adult mortality worldwide. Many patients experience persistent symptoms despite revascularization procedures and modern medical treatment. Experimental studies demonstrated that cardiac shock wave therapy (CSWT) might promote angiogenesis and improve myocardial function in a model of myocardial ischemia. The purpose of our study was to study the impact of CSWT on exercise tolerance, angina symptoms, myocardial perfusion and contraction during stress in patients with CAD and objective evidence of myocardial ischemia, who are not candidates for traditional revascularization and experience angina despite optimal medical therapy. The systematic review and metaanalysis demonstrated that CSWT is a potentially effective new non-invasive option for patients with CAD, but up till now evidence was limited to small, single-centre studies with high risk of bias due to the absence of credible control and allocation procedures. The randomized, triple-blind, sham procedure controlled study included 72 patients, from 2 centres. Clinical variables improved in both intervention and placebo groups. The anti-ischemic CSWT effect is clearly proven by cardiac imaging techniques and ECG changes during stress (on perfusion, contractility and extent of myocardial ischemia). This study presumably shows the substantial reserve of symptomatic improvement in optimizing medical treatment and patients’ adherence
Efficacy of extracorporeal shockwave myocardial revascularization therapy in patients with stable angina pectoris: the randomized, triple-blind, sham procedure controlled study.
No full textCoronary artery disease (CAD) is recognized to be a leading reason of adult mortality worldwide. Many patients experience persistent symptoms despite revascularization procedures and modern medical treatment. Experimental studies demonstrated that cardiac shock wave therapy (CSWT) might promote angiogenesis and improve myocardial function in a model of myocardial ischemia. The purpose of our study was to study the impact of CSWT on exercise tolerance, angina symptoms, myocardial perfusion and contraction during stress in patients with CAD and objective evidence of myocardial ischemia, who are not candidates for traditional revascularization and experience angina despite optimal medical therapy. The systematic review and metaanalysis demonstrated that CSWT is a potentially effective new non-invasive option for patients with CAD, but up till now evidence was limited to small, single-centre studies with high risk of bias due to the absence of credible control and allocation procedures. The randomized, triple-blind, sham procedure controlled study included 72 patients, from 2 centres. Clinical variables improved in both intervention and placebo groups. The anti-ischemic CSWT effect is clearly proven by cardiac imaging techniques and ECG changes during stress (on perfusion, contractility and extent of myocardial ischemia). This study presumably shows the substantial reserve of symptomatic improvement in optimizing medical treatment and patients’ adherence
Specializuotos fizinių treniruočių / reabilitacijos programos prieinamumas ir efektyvumas pacientams, sergantiems plautine hipertenzija ir širdies nepakankamumu.
No full textPulmonary hypertension (PH) and chronic heart failure (HF) are severe cardiovascular disorders, both of which are characterised by reduced physical capacity of the patients and poor survival. Despite modern treatment options, most PH patients still suffer from symptoms, poor health related quality of life and disease progression. The thesis evaluates the feasibility, safety and efficacy of a specialised rehabilitation programme in addition to optimal medical therapy in patients with precapillary and post-capillary PH. A prospective, multicentre, randomised, usual care controlled trial showed that a specialised rehabilitation programme is safe and effective for precapillary PH patients. This thesis also collects and describes data on organisational aspects that fill the knowledge gap and promote the use of PH rehabilitation in dedicated PH centres. This study also presents a systematic literature review, assessing the scientific evidence on the effects of exercise training and physiotherapy on cardiac morphological, functional and pulmonary blood flow parameters in patients, diagnosed with heart failure with preserved ejection fraction (HFpEF) and shares a newly developed multicentre study protocol to assess the effects of exercise training on PH-HFpEF patients
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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