55801 research outputs found
Sort by
Analysing the trade-off between transparency and efficiency in the Council of the European Union
Is derelict fishing gear impacting the biodiversity of the Northern Adriatic Sea? An answer from unique biogenic reefs
The Fifth-Century AD Riverine Barge of Santa Maria in Padovetere (Ferrara, Italy): A Multidisciplinary Approach to its Environment and Shipbuilding Techniques
Lombard terms and Latin glosses from the Codex Eporedianus of the Edictum Rothari
The Edictum Rothari is the frst code of Lombard traditional common law, written down by order of king Rothari, and accepted in November 643 in Pavia by a gairethinx, an assembly of the army. The Edict forms the basis of all later Lombard law collections, the so-called Leges Langobardorum, ranging from Rothari (643) to Aistulf (755), and is followed in some codices by the additional titles issued by the Beneventan princes Arichis and Adelchis in 774 and 866, respectively. Though an evaluation of the juridical implications of the Leges exceeds the scope of this essay, it should be emphasised that the political and ideological value of the Edict is evident in the fact that all later laws depend on this text – albeit in different ways; the latter is thus widely recognised as the founding document of the Lombard juridical tradition
Pragmatica nell’uso dei pronomi clitici diretti di terza persona singolare in bambini dislessici con e senza disturbo specifico del linguaggio
Omission of direct object clitic pronouns (DOCLs) is a cross-linguistically spread phenomenon
among children with Specific Language Impairment (SLI). Children with Developmental
Dyslexia (DD) also display difficulties with the production of DOCLs. Besides (morpho)syntactic
skills, clitic use requires a range of abilities including pragmatic skills. The present study explores
the role of pragmatics in the omission of DOCLs in Italian.
Various pragmatically inadequate strategies are used by SLI and younger DD children in order
to compensate for (morpho)syntactic deficits, such as the production of noun phrases to avoid
clitic pronouns, present-perfect sentences with contracted clitics instead of antecedent-clitic
agreement, and sentences that are unrelated to the context. After age 10, DD children show no
difficulties anymore, suggesting that different reasons may underlie problems in using DOCLs
by SLI and DD children
Revolutionärer Konservativismus als Modell. Vom späten Friedrich Schlegel zum späten Hugo von Hofmannsthal
Mixed Fluorinated/Hydrogenated Self-Assembled Monolayer-Protected Gold Nanoparticles: In Silico and In Vitro Behavior
Gold nanoparticles (AuNPs) covered with mixtures of immiscible ligands present potentially anisotropic surfaces that can modulate their interactions at complex nano-bio interfaces. Mixed, self-assembled, monolayer (SAM)-protected AuNPs, prepared with incompatible hydrocarbon and fluorocarbon amphiphilic ligands, are used here to probe the molecular basis of surface phase separation and disclose the role of fluorinated ligands on the interaction with lipid model membranes and cells, by integrating in silico and experimental approaches. These results indicate that the presence of fluorinated amphiphilic ligands enhances the membrane binding ability and cellular uptake of gold nanoparticles with respect to those coated only with hydrogenated amphiphilic ligands. For mixed monolayers, computational results suggest that ligand phase separation occurs on the gold surface, and the resulting anisotropy affects the number of contacts and adhesion energies with a membrane bilayer. This reflects in a diverse membrane interaction for NPs with different surface morphologies, as determined by surface plasmon resonance, as well as differential effects on cells, as observed by flow cytometry and confocal microscopy. Overall, limited changes in monolayer features can significantly affect NP surface interfacial properties, which, in turn, affect the interaction of SAM-AuNPs with cellular membranes and subsequent effects on cells