695915 research outputs found
Sort by
Inflammatory Fabry cardiomyopathy demonstrated using simultaneous hybridised 18F-fluorodeoxyglucose positron emission tomography, cardiovascular magnetic resonance imaging
No full textUsing hybridised 18FDG-PET-CMR, we identify active myocardial inflammation, and demonstrate its relationship with late gadolinium enhancement, in Fabry disease. We demonstrate that LGE represents, at least in part, active myocardial inflammation, and identify an early inflammatory phenotype which may represent a therapeutic window before irreversible tissue injury and adaptation occurs
B-fields do not suppress star formation in low metallicity dwarf galaxies
No full textMany studies have looked at the impact of magnetic fields on star formation in molecular clouds and Milky Way like galaxies, concluding that the field suppresses star formation. However, most of these studies are based on fully developed fields that have reached the saturation level, with little work on investigating how the growth phase of a primordial field affects star formation in low metallicity environments. In this paper, we investigate the impact of the growth phase of a primordial field on low metallicity dwarf galaxies. We perform high-resolution arepo simulations of 5 isolated dwarf galaxies. Two models are hydrodynamical, two start with a primordial B-field of 10−6µG, and one with a saturated B-field of 10−2µG. All models include a non-equilibrium, time-dependent chemical network that includes the effects of gas shielding from the ambient UV field. Sink particles form directly from the gravitational collapse of gas and are treated as star-forming clumps that can accrete gas. We vary the metallicity, UV-field, and cosmic ray ionization rate between 1% and 10% of solar values. We find that the magnetic field has little impact on the star formation rate, which is in tension with previously published results. We show that an increase in the mass fractions of both molecular hydrogen and cold gas, along with changes in the perpendicular gas velocity dispersion’s and the B-field acting in the weak-field model overcomes the expected suppression in star formation.<br/
Nurses perception of what makes a good care experience for children and young people with intellectual disabilities align with parents' perceptions.
No full textCommentary on: Mimmo L, Hodgins M, Samir N, Travaglia J, Woolfenden S, Harrison R. 'Smiles and laughter and all those really great things': Nurses' perceptions of good experiences of care for inpatient children and young people with intellectual disability. J Adv Nurs. 2022 Sep;78(9):2933-2948. doi: 10.1111/jan.15256. Epub 202
The impact of performance-based financing within local health systems: Evidence from Mozambique
No full textMost evidence on Performance Based Financing (PBF) in low-income settings has focused on services delivered by providers in targeted health administrations, with limited understanding of how effects on health and care vary within them. We evaluated the population effects of a programme implemented in two provinces in Mozambique, focusing on child, maternal and HIV/AIDS care and knowledge. We used a difference-in-difference estimation strategy applied to data on mothers from the Demographic Health Surveys, linked to information on their closest health facility. The impact of PBF was limited. HIV testing during antenatal care increased, particularly for women who were wealthier, more educated or residing in Gaza Province. Knowledge about transmission of HIV from mother-to-child, and its prevention, increased, particularly for women who were less wealthy, less educated, and residing in Nampula. Exploiting the roll-out by facility, we found that the effects were concentrated on less wealthy and less educated women, whose closest facility was in the referral network of a PBF facility. Results suggest that HIV testing and knowledge promotion increased in the whole district as a strategy to boost referral for highly incentivised HIV services delivered in PBF facilities. However, demand-side constraints may prevent the use of those services
Book review symposium: [Un]Grounding:Friederike Landau, Lucas Pohl, and Nikolai Roskamm (eds), [Un]Grounding: Post- Foundational Geographies, Bielefeld: transcript, 2021; 348 pp.: ISBN: 9783837650730, £47.99/€50,00 (pbk)
No full textAn Incremental Cognitive Architecture of Consciousness with Global Workspace Theory
No full textThis paper revisits the GlobalWorkspace Theory as a neuroscientifically plausible theory for developing conscious cognitive architecture. Based on the discussion of the authors’ previous implementations, the Global Workspace Theory’s compatibility with the working mechanisms underneath human brains is enhanced by demonstrating cognitive features of attention and consciousness. To progress in the incremental research pathway for the architecture implementation, two principles of work are stressed. The primitive cognitive mechanisms are emphasised more than the functional complexity and the revision-update cycle for implementation is appreciated for its engineering feasibility. Along the incremental pathway, the idea for possible following attempts is shared. Based on the discussion of completed and following implementations, the authors’ works are consistent with the Biologically Inspired Cognitive Architecture roadmap
Transforming Chinese consumers’ environmental concerns and eco-label awareness into willingness to pay for eco-labelled food products
No full textThe purpose of this paper is to model the antecedents of consumers’ willingness to pay for eco-labelled food products. The research utilises the Theory of Planned behaviour (TPB) to model the impact of consumers’ awareness of eco-label, environmental concern, belief in the environmental ability of eco-label and presence of children on their willingness to pay for eco-labelled food products. The study uses Structural Equational Modelling (SEM) and PROCESS macros, to test the moderated mediation model on a sample of 333 online responses. Findings suggest the impact of consumers’ environmental concerns and eco-label awareness on their willingness to pay for eco-labelled food products is partially mediated by consumers' belief in the environmental ability of these eco-labels. The relationship is also further moderated by the presence of children living in the household. The study establishes the value of consumers’ belief in the environmental ability of eco-labels and implies that communication strategies need to be carefully refined to provide consumers with more information about eco-labels and to emphasise the environmental ability of eco-labels utilised within the food industry as this can have an impact on their willingness to pay for these products especially for consumers with children living with them
Semimetallic and semiconducting graphene-hBN multilayers with parallel or reverse stacking
No full textWe theoretically investigate 3D layered crystals of alternating graphene and hBN layers with different symmetries. Depending on the hopping parameters between the graphene layers, we find that these synthetic 3D materials can feature semimetallic, gapped, or Weyl semimetal phases. Using first-principles calculations to parameterize the low-energy Hamiltonians we establish the most likely electronic phases. Our results demonstrate that 3D crystals stacked from individual 2D materials represent a new materials class with emergent properties different from their constituents
Impact of Two-Phase Flow Pattern on Solvent Vapour Extraction
No full textSolvent Vapour extraction (Vapex) is a promising technology for in-situ heavy oil recovery from oil sands deposits. The prediction of oil recovery rates requires fundamental understanding of the pore-scale mechanisms and their impact on mass transfer and oil production. To bridge the gap between pore-scale mechanisms and macro scale recovery, a dynamic pore-network model for two-phase flow with mass transfer is developed. The impact of pressure gradient on two-phase flow pattern, mass transfer and oil production are investigated. It is found that at high capillary numbers, in viscous dominated flow, dissolved oil is moved in intermittent liquid clusters to the outlet of the network. This mechanism of interface renewal maintains a steep solvent mole fraction gradient at the interface and enhances mass transfer, resulting in high oil production. In capillary dominated flow, capillary fingering with low mass transfer and oil production are observed