22282 research outputs found
Sort by
Research utilisation or knowledge mobilisation by health managers: Synthesising evidence and theory using perspectives of organisational form, resource based view of the firm and critical theory
No full textThe literature review builds on an earlier Scoping Review of the literature on knowledge mobilization (Crilly et al, 2010; Ferlie at al, 2012) which identified a gap in the healthcare literature and proposed work in three defined areas or domains. The first is Resource Based View of the Firm, a strategic management concept that examines how differences in capabilities, including knowledge, allow one firm to outperform another. There is no equivalent in healthcare. It states that strategic resources that are valuable, rare, difficult to imitate, and able to be exploited by organizational processes (VRIO principles), will give the firm a sustainable competitive advantage. The second is termed the Critical Perspective, concerned with power and authority in the workplace, which is alive to tensions between occupational groups such as doctors and managers. Two strands of particular interest are Foucauldian and neo-Marxist labour process critical theories. The third area is organizational form, which considers whether certain types of organization, such as networks, are better than others at mobilizing knowledge
Multi-photon quantum interference in a multi-port integrated photonic device
No full textIncreasing the complexity of quantum photonic devices is essential for many optical information processing applications to reach a regime beyond what can be classically simulated, and integrated photonics has emerged as a leading platform for achieving this. Here, we demonstrate three-photon quantum operation of an integrated device containing three coupled interferometers, eight spatial modes and many classical and nonclassical interferences. This represents a critical advance over previous complexities and the first on-chip nonclassical interference with more than two photonic inputs. We introduce a new scheme to verify quantum behaviour, using classically characterised device elements and hierarchies of photon correlation functions. We accurately predict the device's quantum behaviour and show operation inconsistent with both classical and bi-separable quantum models. Such methods for verifying multiphoton quantum behaviour are vital for achieving increased circuit complexity. Our experiment paves the way for the next generation of integrated photonic quantum simulation and computing devices
Diagnosis of tumors during tissue-conserving surgery with integrated autofluorescence and Raman scattering microscopy
No full textTissue-conserving surgery is used increasingly in cancer treatment. However, one of the main challenges in this type of surgery is the detection of tumor margins. Histopathology based on tissue sectioning and staining has been the gold standard for cancer diagnosis for more than a century. However, its use during tissue-conserving surgery is limited by time-consuming tissue preparation steps (1–2 h) and the diagnostic variability inherent in subjective image interpretation. Here, we demonstrate an integrated optical technique based on tissue autofluorescence imaging (high sensitivity and high speed but low specificity) and Raman scattering (high sensitivity and high specificity but low speed) that can overcome these limitations. Automated segmentation of autofluorescence images was used to select and prioritize the sampling points for Raman spectroscopy, which then was used to establish the diagnosis based on a spectral classification model (100% sensitivity, 92% specificity per spectrum). This automated sampling strategy allowed objective diagnosis of basal cell carcinoma in skin tissue samples excised during Mohs micrographic surgery faster than frozen section histopathology, and one or two orders of magnitude faster than previous techniques based on infrared or Raman microscopy. We also show that this technique can diagnose the presence or absence of tumors in unsectioned tissue layers, thus eliminating the need for tissue sectioning. This study demonstrates the potential of this technique to provide a rapid and objective intraoperative method to spare healthy tissue and reduce unnecessary surgery by determining whether tumor cells have been removed
Young adults and ‘binge’ drinking: A Bakhtinian analysis
Get PDFIn this paper we use Bakhtin’s theory of carnival in a literary analysis of young peoples’ accounts of the role of alcohol in their social lives. Bakhtinian themes in the focus group transcripts included the dialogic character of drinking stories, the focus on parodic grotesquery, ribald and satiric laughter, and the temporary subversion and reversal of social norms and roles in a world turned ‘inside out’. We suggest that our analysis of the UK’s drinking ‘culture’ hints at a previously untheorised complexity and force, and points to a deep contradiction between young peoples’ lived experience of alcohol and government policy discourses based on appeals to individual moral responsibility. We conclude that the carnivalesque resonance of drinking is such that the UK’s alcohol problem will continue to worsen until the availability and cultural presence of alcohol is subject to stricter controls
Accountability and performance management systems within private and public sector organisational change processes
No full textThis paper examines organisational change processes that occur when accountability demands from powerful external stakeholders change. It investigates, firstly, whether these external accountability demands impact on the performance management systems of two different types of organisations. Secondly, it considers whether the goals for improved performance contained within the external accountability demands are realised. The paper derives its primary insights from analysing in-depth interviews with managers working in a private sector company and in public sector organisations. The analyses reveal complex organisational responses. In the public sector case study, the organisations tended to reorient their performance management systems towards the external accountability demands; whilst in the private sector organisation, pressures from falling share prices forced managers to focus their decision making on the preferred performance measures contained in shareholders’ accountability demands. However, whilst there is some evidence of performance management system changes, the desires for improved performance subsumed by the external accountability demands are not necessarily realised through the performance management system changes
A model for dynamic reconfiguration in service-oriented architectures
No full textThe importance of modelling the dynamic characteristics of the architecture of software systems has long been recognised. However, the nature of the dynamics of service-oriented applications goes beyond what is currently addressed by architecture description languages (ADLs). At the heart of the service-oriented approach is the logical separation between the service need and the need-fulfillment mechanism, i.e., the provision of the service: the binding between the requester and the provider is deferred to run time and established at the instance level, i.e., each time the need for the service arises. As a consequence, computation in the context of service-oriented architectures transforms not only the states of the components that implement applications but also the configurations of those applications. In this paper, we present a model for dynamic reconfiguration that is general enough to support the definition of ADLs that are able to address the full dynamics of service-oriented applications. As an instance of the model, we present a simple service-oriented ADL derived from the modelling language srml that we developed in the Sensoria project. © 2012 Springer-Verlag
Young adults and ‘binge’ drinking: A Bakhtinian analysis
No full textIn this paper we use Bakhtin’s theory of carnival in a literary analysis of young peoples’ accounts of the role of alcohol in their social lives. Bakhtinian themes in the focus group transcripts included the dialogic character of drinking stories, the focus on parodic grotesquery, ribald and satiric laughter, and the temporary subversion and reversal of social norms and roles in a world turned ‘inside out’. We suggest that our analysis of the UK’s drinking ‘culture’ hints at a previously untheorised complexity and force, and points to a deep contradiction between young peoples’ lived experience of alcohol and government policy discourses based on appeals to individual moral responsibility. We conclude that the carnivalesque resonance of drinking is such that the UK’s alcohol problem will continue to worsen until the availability and cultural presence of alcohol is subject to stricter controls
Diagnosis of tumors during tissue-conserving surgery with integrated autofluorescence and Raman scattering microscopy
No full textTissue-conserving surgery is used increasingly in cancer treatment. However, one of the main challenges in this type of surgery is the detection of tumor margins. Histopathology based on tissue sectioning and staining has been the gold standard for cancer diagnosis for more than a century. However, its use during tissue-conserving surgery is limited by time-consuming tissue preparation steps (1–2 h) and the diagnostic variability inherent in subjective image interpretation. Here, we demonstrate an integrated optical technique based on tissue autofluorescence imaging (high sensitivity and high speed but low specificity) and Raman scattering (high sensitivity and high specificity but low speed) that can overcome these limitations. Automated segmentation of autofluorescence images was used to select and prioritize the sampling points for Raman spectroscopy, which then was used to establish the diagnosis based on a spectral classification model (100% sensitivity, 92% specificity per spectrum). This automated sampling strategy allowed objective diagnosis of basal cell carcinoma in skin tissue samples excised during Mohs micrographic surgery faster than frozen section histopathology, and one or two orders of magnitude faster than previous techniques based on infrared or Raman microscopy. We also show that this technique can diagnose the presence or absence of tumors in unsectioned tissue layers, thus eliminating the need for tissue sectioning. This study demonstrates the potential of this technique to provide a rapid and objective intraoperative method to spare healthy tissue and reduce unnecessary surgery by determining whether tumor cells have been removed
Young Adults and ‘Binge’ Drinking: A Bakhtinian Analysis
No full textIn this paper we use Bakhtin’s theory of carnival in a literary analysis of young peoples’ accounts of the role of alcohol in their social lives. Bakhtinian themes in the focus group transcripts included the dialogic character of drinking stories, the focus on parodic grotesquery, ribald and satiric laughter, and the temporary subversion and reversal of social norms and roles in a world turned ‘inside out’. We suggest that our analysis of the UK’s drinking ‘culture’ hints at a previously untheorised complexity and force, and points to a deep contradiction between young peoples’ lived experience of alcohol and government policy discourses based on appeals to individual moral responsibility. We conclude that the carnivalesque resonance of drinking is such that the UK’s alcohol problem will continue to worsen until the availability and cultural presence of alcohol is subject to stricter controls
Data sources:
Access Repository Dashboard
Do you manage Royal Holloway? Access insider analytics, issue reports and manage access to outputs from your repository in the CORE Repository Dashboard!