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Household status and socioeconomic determinants of divorce among married women in Nigeria a pooled data analysis
Agrarian transitions in rural Bushbuckridge Mpumalanga province South Africa understanding dynamics and determinants
Porescale evaluation on hydrothermal performance in a microtube with homogeneous microporous media by lattice Boltzmann method
Caregiver challenges and opportunities for accessing early hearing detection and intervention A narrative inquiry from South Africa
The Crystal and Molecular Structure of Nmethylephedrinium 4nitrobenzoate I II Racemic Mimic Part 5
Ephedrine is an ancient Chinese medicine drug used on patients with asthma, bronchitis and hay fever. In more recent times, it is used to prevent low blood pressure during anesthesia and to treat narcolepsy and obesity. It seemed important to understand the interaction of this drug with as large a variety of substrates as possible to get hints as to its modus operandi.
It was, therefore, of interest that it appeared to crystallize as a Racemic Mimic in the form of its 4-nitrobenzoate derivative as determined by the cell parameters of that salt when it crystallized in both racemic and Sohncke space groups. Below, we describe the procedure used to prove that ephedrine belongs in that class and to illustrate the nature of the intra- and intermolecular interactions between the constituent moieties in that monoclinic (P21 and P21/c) pair. Both crystal structures,obtained from the literature, were determined at 123 K and refined, respectively, to R-factors of 3.73 and 5.51%