19683 research outputs found
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Delivery of Neuropsychological Interventions for Adult and Older Adult Clinical Populations: An Australian Expert Working Group Clinical Guidance Paper
No full textDelivery of neuropsychological interventions addressing the cognitive, psychological, and behavioural consequences of brain conditions is increasingly recognised as an important, if not essential, skill set for clinical neuropsychologists. It has the potential to add substantial value and impact to our role across clinical settings. However, there are numerous approaches to neuropsychological intervention, requiring different sets of skills, and with varying levels of supporting evidence across different diagnostic groups. This clinical guidance paper provides an overview of considerations and recommendations to help guide selection, delivery, and implementation of neuropsychological interventions for adults and older adults. We aimed to provide a useful source of information and guidance for clinicians, health service managers, policy-makers, educators, and researchers regarding the value and impact of such interventions. Considerations and recommendations were developed by an expert working group of neuropsychologists in Australia, based on relevant evidence and consensus opinion in consultation with members of a national clinical neuropsychology body. While the considerations and recommendations sit within the Australian context, many have international relevance. We include (i) principles important for neuropsychological intervention delivery (e.g. being based on biopsychosocial case formulation and person-centred goals); (ii) a description of clinical competencies important for effective intervention delivery; (iii) a summary of relevant evidence in three key cohorts: acquired brain injury, psychiatric disorders, and older adults, focusing on interventions with sound evidence for improving activity and participation outcomes; (iv) an overview of considerations for sustainable implementation of neuropsychological interventions as ‘core business’; and finally, (v) a call to action.</p
<b>Data File</b>: Assessing working memory function in individuals with fibromyalgia: A systematic review and meta-analysis
No full textThis is the data file associated with a publication of the same name.</p
The impact of chronic fluoxetine treatment in adolescence or adulthood on context fear memory and perineuronal nets
No full textSelective serotonin reuptake inhibitors, such as fluoxetine (Prozac), are commonly prescribed pharmacotherapies for anxiety. Fluoxetine may be a useful adjunct because it can reduce the expression of learned fear in adult rodents. This effect is associated with altered expression of perineuronal nets (PNNs) in the amygdala and hippocampus, two brain regions that regulate fear. However, it is unknown whether fluoxetine has similar effects in adolescents. Here, we investigated the effect of fluoxetine exposure during adolescence or adulthood on context fear memory and PNNs in the basolateral amygdala (BLA), the CA1 subregion of the hippocampus, and the medial prefrontal cortex in rats. Fluoxetine impaired context fear memory in adults but not in adolescents. Further, fluoxetine increased the number of parvalbumin (PV)-expressing neurons surrounded by a PNN in the BLA and CA1, but not in the medial prefrontal cortex, at both ages. Contrary to previous reports, fluoxetine did not shift the percentage of PNNs toward non-PV cells in either the BLA or CA1 in the adults, or adolescents. These findings demonstrate that fluoxetine differentially affects fear memory in adolescent and adult rats but does not appear to have age-specific effects on PNNs.</p
Care ethics and contemporary art: Imagining and practising care
No full textAbstract: Feminist care ethics has for some time guided contemporary artists and curators in their search for sustaining and sustainable practices in the current neoliberal backwash and climate crisis. With a focus on current Australian art in the context of recent care ethics scholarship, this article considers what contemporary art – in its processes as well as aesthetic outcomes – can offer in imagining and practising care for the human and more-than-human world. The article focuses on a series of exhibitions that comprised a key exploratory methodology of The Care Project: Feminism and art in neoliberal times (La Trobe University, 2019–2022). The exhibitions featured the work of regionally based artists. This accent on creative practices emerging from the experience of living in regional communities that are often on the frontline of climate change and social inequality offers unique perspectives on care ethics in practice.</p
Moral Injury for LGBTQ+ Individuals and their Communities
No full textIntroduction: Moral injury describes the severe distress and associated impairments that result from experiencing specific traumatic events. These are events that violate the values or core beliefs of the injured person, and are often directed from a person in a position of power. Research on moral injury is not new, but has typically had a limited focus (e.g., on moral injury sustained during war) and has only recently begun to focus on the context and severity of moral injuries for individuals from minoritized communities. Contents of Paper: This paper: (a) puts forward a case that members of the LGBTQ+ communities are at-risk individuals for moral injury, and in particular religious or spiritual injuries; (b) presents the findings of a scoping review (using a systematic search) that evaluates the extant evidence on LGTBQ + moral injury, and; (c) details a series of considerations for practitioners who are supporting LGBTQ+ survivors of moral injury. Conclusion: We close this paper with an urgent call for more on the scope and nature of moral injury for LGBTQ+ individuals and their communities, in order to help better inform interventions and other forms of support for survivors.</p
Training to improve emergency management decision-making: what the research literature tells us
No full textThe importance of training for effective performance in high-stakes, high-risk work settings is well-known. Successful training is the systematic acquisition of skills, rules, concepts or attitudes that result in improved work performance. Simply exposing people to training situations is not sufficient for them to develop knowledge and skills. This will only occur if the activity results in learning. While much training focuses on the development of technical skills, it is important to train people in non-technical skills, such as decision-making. This paper presents the results of a literature review of 95 peer-reviewed articles that consider the current training and exercise practices used to develop emergency management decision-making capability. The different approaches to training can be categorised into 4 types: discussion-based, operation-based, E-based and post-incident debriefs. This paper discusses current practice in emergency management decision-making training in each of these categories together with studies that have evaluated their effectiveness noting the generally limited nature of evaluation studies. To promote evaluation of training, several studies have developed tools to assess the effectiveness of training. Finally, key takeaway points related to emergency management organisational training and exercise programs are provided.</p
Classification of epidermal, buccal, penile and vaginal epithelial cells using morphological characteristics measured by imaging flow cytometry
No full textAs a result of the increased sensitivity of forensic DNA techniques, which can generate informative results from as little as a few cells, developing an understanding of the anatomical region these cells originate from is becoming more pertinent. Imaging Flow Cytometry (IFC) represents a promising method for identifying epithelial cells from different anatomical regions. This project aimed to determine whether IFC could be used to distinguish epithelial cells collected from different forensically relevant anatomical regions based on their morphology and autofluorescence. Penile, vaginal, buccal, and epidermal epithelial cells were collected in triplicate from 15 male and 15 female participants, in three different age groups: 18–39, 40–59, and 60+ years. Using the high statistical output from the IFC, 234 morphological measurements were collected for 571,546 single cells. Using a linear discriminate analysis with a minimum posterior probability threshold, the four epithelial cell types could be identified and distinguished with a 72–83 % classification accuracy. The results showed that the age and biological sex of the individual had no effect on the morphology of the four epithelial cell types. These data provide insights into the ability of IFC to identify and distinguish penile, buccal, vaginal, and epidermal epithelial cells and identifies further avenues for improvement and optimisation.</p
Characteristics of attrition within the SuperMIX cohort of people who inject drugs: a multiple event discrete-time survival analysis
No full textBACKGROUND: Compared to the general population, people who inject drugs have poor health and wellbeing. Longitudinal studies can provide insight into factors driving these worse health outcomes but are subject to methodological challenges, such as cohort attrition. The aim of this study was to assess and characterise attrition in a prospective cohort of people who inject drugs in Victoria, Australia. METHODS: Using annually collected self-reported data from The Melbourne Injecting Drug User Cohort Study (SuperMIX) from September 2008 to January 2021, we estimated the incidence of participants being lost-to-follow-up (LTFU), with an episode of being LTFU defined as participants not undertaking a follow-up interview within two years of their last interview. We utilised a multiple event discrete-time survival analysis on participant period-observation data to estimate the associations between key factors and LTFU. Key areas of exposure measurement in analyses were sociodemographic, drug use and mental health. RESULTS: A total of n = 1328 SuperMIX participants completed a baseline interview, with n = 489 (36.8%) LTFU, i.e. not completing a follow-up interview in the following two years. Increased attrition was observed among SuperMIX participants who were: born outside Australia, younger than 30 years, reporting having completed fewer years of education, not residing in stable accommodation, not in stable employment and not on opioid agonist therapy (OAT). CONCLUSIONS: The attrition rate of the SuperMIX cohort has largely been stable throughout the duration of the study. Higher attrition rates among individuals at greater sociodemographic disadvantage and not on OAT suggest that additional efforts are required to retain these participants. Findings also suggest that SuperMIX might not be capturing data on adverse health and wellbeing outcomes among subpopulations at high risk of harm.</p
Characteristics of successful performance support team members at the Olympic games
No full textObjectives: Athletes and coaches rely on their performance support team to optimise training and competition. The specific characteristics of performance support teams that contribute to success in competition from the perspective of athletes and coaches have not been examined. Olympic gold medal winning athletes and coaches were asked about the characteristics they valued in the performance support team members who were with them at the Olympic Games. The insights shared provide important context to the role of the performance support team member, beyond technical skills, in the high-stress environment of elite sporting competition. Methods: Concept mapping was completed online to collect, analyse, and visually represent insights from 30 Olympic gold medal winning athletes and coaches. The concept mapping focus prompt used to generate insights from participants was ‘When I reflect on my gold medal winning performance, a characteristic that I really valued within my support team was….’. Athletes then brainstormed, sorted, and rated relevant statements. Results: Multidimensional scaling and hierarchical cluster analysis produced an 8-cluster map – Way of Working, Communication Style, Emotional Management in Competition, Teamwork, Commitment to Athlete Preparation, Professionalism, Embracing the Experience, and Equality – as the best visual representation of the way participants sorted the 49 unique brainstormed statements. Conclusions: Olympic gold medal winning athletes and coaches prioritised ways of working, communication style, emotional management, and teamwork as the characteristics they valued most in their performance support team. These constructs, when further examined by item, encourage performance support staff to develop emotional management skills to (a) strengthen interpersonal relationships within the team, (b) enhance the working alliance with athletes and coaches, and (c) contribute to team performance overall. Concept mapping provided a structured way of collecting lived experience insights that may compliment other qualitative approaches such as structured interviews.</p
Effectiveness of interventions to increase physical activity in adults with SCI: a systematic review and meta-analysis
No full textPurpose: To determine the effectiveness of interventions to increase physical activity (PA) in people with spinal cord injury (SCI). Method: Online databases PubMed, Medline, AMED and CINAHL were searched from the earliest date available to July 2022. Randomised controlled trials (RCT) exploring the effect of interventions on physical activity in people with SCI were eligible. The search identified 1191 studies, after screening 16 reports of 15 RCT’s were included. Data were extracted on participant characteristics, intervention characteristics and physical activity outcomes. Methodological quality was assessed using the PEDro Scale and certainty of evidence assessed using GRADE. Post intervention means and standard deviations were pooled in meta-analyses to calculate standardised mean differences or mean differences and 95% confidence intervals. Results: Fifteen trials with 693 participants (mean age 41–52) were included. There was moderate certainty evidence that exercise interventions had no effect on subjectively or objectively measured PA. There was moderate to high certainty evidence that behavioural interventions and combined behavioural and exercise interventions increased subjectively, but not objectively measured physical activity. Conclusion: Behaviour change techniques are an important intervention component for increasing PA in people with SCI.IMPLICATIONS FOR REHABILITATION Only half of people with spinal cord injury (SCI) meet physical activity guidelines Physical activity (PA) is important in managing primary and secondary complications Exercise intervention alone does not increase PA in people with SCI Interventions should include behavioural techniques to increase PA in people with SCI Interventions that include behavioural techniques are shown to be effective across a wide range of SCI populations.</p