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Age-Related Differences in the Functional Demand Placed on the Lumbar Spine during Walking in Healthy Older versus Younger Men
No full textAge-related declines in the musculoskeletal system may place additional demands on the lumbar spine during everyday activities such as walking. This study aimed to investigate age-related differences in the functional demand (FD) of walking on the lumbar spine in older and younger adults. A motion analysis system with integrated force plates was used to acquire kinematic and kinetic data on 12 older (67.3 ± 6.0 years) and 12 younger (24.7 ± 3.1 years) healthy men during walking at a self-selected speed along a 10 m walkway. Isokinetic dynamometry was used to acquire the maximal joint moment capacity of the lumbar spine. The FD of the lumbar spine was calculated as the muscle moment during key phases of the gait cycle (GC) relative to the maximum moment capacity of the lumbar spine. The difference in FD between age groups was not significant (p = 0.07) and there were no significant differences between the young group (YG) and older group (OG) for any individual phase in the GC. Despite the lack of statistical significance, the results indicate that a practical difference may exist, as walking was approximately 20% more functionally demanding on the lumbar spine in the OG compared to the YG. Therefore, older adults may employ modified gait strategies to reduce mechanical load whilst walking to fall within the limits of their maximal force-producing capacity in the lumbar spine, which may have implications for injury risk.</p
CellShip:An Ambient Temperature Transport and Short-Term Storage Medium for Mammalian Cell Cultures
No full textCell culture is a critical platform for numerous research and industrial processes. However, methods for transporting cells are largely limited to cryopreservation, which is logistically challenging, requires the use of potentially cytotoxic cryopreservatives, and can result in poor cell recovery. Development of a transport media that can be used at ambient temperatures would alleviate these issues. In this study, we describe a novel transportation medium for mammalian cells. Five commonly used cell lines, (HEK293, CHO, HepG2, K562, and Jurkat) were successfully shipped and stored for a minimum of 72 hours and up to 96 hours at ambient temperature, after which, cells were recovered into standard culture conditions. Viability (%) and cell numbers, were examined, before, following the transport/storage period and following the recovery period. In all experiments, cell numbers returned to pretransport/storage concentration within 24-48 hours recovery. Imaging data indicated that HepG2 cells were fully adherent and had established typical growth morphology following 48 hours recovery, which was not seen in cells recovered from cryopreservation. Following recovery, Jurkat cells that had been subjected to a 96 hours transport/storage period, demonstrated a 1.93-fold increase compared with the starting cell number with >95% cell viability. We conclude that CellShip® may represent a viable method for the transportation of mammalian cells for multiple downstream applications in the Life Sciences research sector.</p
Challenges in reporting on the United Nations Sustainable Development Goals: a management accounting focus
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What are the right configurations of just-in-time and just-in-case when supply chain shocks increase?
Get PDFDeveloping guidelines on EFT for same-sex/gender relationships: Recommendations from a Delphi study
Get PDFEmotionally focused therapy (EFT) is one of few empirically supported treatments for relationship distress. While evidence-based approaches are critical for ensuring safe and effective treatment, EFT has not been adapted for use with same-sex/same-gender (SS/SG) relationships. This study used the Delphi method to generate consensus on treatment guidelines for using EFT with SS/SG relationships. Forty therapists with clinical expertise in EFT for SS/SG relationships were recruited. Data were collected in three phases. In phase one, participants responded to open-ended questions regarding how EFT should be adapted for SS/SG relationships. Phases two and three involved participants rating the importance of the recommended guidelines. Data were analyzed using thematic analysis and descriptive statistics. The final recommendations included 49 guidelines on EFT for SS/SG relationships. The data reflected modifications to therapists' foundational knowledge and development, practice set up and orientation, and the three stages and nine steps of EFT
Food waste mitigation in Pakistan hotel industry through implementing integrated Lean supply chain practices for sustainable development.
Get PDFThe governance, leadership and management of complementary schools: the case of Greek Cypriot schools in England
No full textThe article explores the governance, leadership and management of complementary schools through the case of Greek Cypriot complementary schools in England with a view to developing a research agenda for this under-researched yet significant sector of education for children and young people. Drawing on stakeholder and bottom-up theories of governance that aim to uncover the intricate networks of groups that surround organisations and the systems in which they exist, we highlight the multiple and sometimes conflicting stakes held. This exploratory research involves interviews with five practitioners in positions of responsibility. The governance, leadership and management of these schools matters because there are concerns about their sustainability requiring a greater appreciation of their contribution, the issues they face and how they make decisions with limited resources. We call for further research to increase the understanding of the sector and to improve the support for practitioners, organisations and communities
