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Hexafluoroisopropanol induces amyloid fibrils of islet amyloid polypeptide by enhancing both hydrophobic and electrostatic interactions
Get PDFThis research was originally published in the Journal of Biological Chemistry. Kotaro Yanagi, Mizue Ashizaki, Hisashi Yagi, Kazumasa Sakurai, Young-Ho Lee and Yuji Goto. Hexafluoroisopropanol Induces Amyloid Fibrils of Islet Amyloid Polypeptide by Enhancing Both Hydrophobic and Electrostatic Interactions. J. Biol. Chem. 2011; 286, 23959-23966. © the American Society for Biochemistry and Molecular Biolog
A Welfare Analysis of Global Patent Protection in a Model with Endogenous Innovation and Foreign Direct Investment
Get PDF* Revised: [09-24, 2009]This paper constructs a North–South quality-ladder model in which foreign direct investment(FDI) is determined by the endogenous location choice of firms, and examines analytically howstrengthening patent protection in the South affects welfare in the South. Strengthening patent protectionincreases the South's welfare by enhancing innovation and FDI, but it also allows the firmswith patents to charge higher prices for their goods, which decreases welfare. However, the modelshows that the former positive welfare effect outweighs the latter negative effect. Moreover, introducingthe strictest form of patent protection in the South, that is, harmonizing patent protection inthe South with that in the North, may maximize welfare in the South as well as in the North. Further,a similar result can also be obtained in a nonscale effect model
