136986 research outputs found
Sort by
A companion to the preclinical common data elements for genomics, transcriptomics, and epigenomics data in rodent epilepsy models. A report of the TASK3-WG4 omics working group of the ILAE/AES joint translational TASK force
No full textThe International League Against Epilepsy/American Epilepsy Society (ILAE/AES) Joint Translational Task Force established the TASK3 working groups to create common data elements (CDEs) for various preclinical epilepsy research disciplines. The aim of the CDEs is to improve the standardization of experimental designs across a range of epilepsy research-related methods. Here, we have generated CDE tables with key parameters and case report forms (CRFs) containing the essential contents of the study protocols for genomics, transcriptomics, and epigenomics in rodent models of epilepsy, with a specific focus on adult rats and mice. We discuss the important elements that need to be considered for genomics, transcriptomics, and epigenomics methodologies, providing a rationale for the parameters that should be collected. This is the first in a two-part series of omics papers with the second installment to cover proteomics, lipidomics, and metabolomics in adult rodents
Spatial Governance of the Unhoused: On Social Death in the Contemporary City
No full textIn this article, we examine tactics in municipal policy and the criminal law regarding socio-spatial governance of unhoused individuals in city spaces. We explore the intentions and effects of tactics such as sweeps, which remove or destroy unhoused people's possessions, move on orders targeting the mobility and immobility of unhoused people and spatial banning which prohibits the presence of unhoused people in particular locations. We argue here that such tactics respond to houselessness by associating the presence of unhoused individuals with that of waste. Examination of legal and municipal tactics managing the presence of unhoused people in public space shows they are being discursively aligned with waste matter, and their presence in city spaces strictly regulated. Such spatial exclusion strategies result in a kind of social death. The article argues tactics of spatial exclusion should be abandoned by recognising the right of unhoused individuals to be in public places
Does Reality Television-Style Singing Influence Singing Self-Concept?
No full textHYPOTHESIS: Due to upward social comparison, we hypothesized that exposure to reality television singing (a technically demanding style of contemporary commercial music singing) would negatively influence singing self-concept compared to hearing amateur singers or plain, unembellished singing by professionals. STUDY DESIGN AND METHODS: A between-subjects, online experiment was used. A sample of 212 individuals (Mage = 33.14; 69.30% female) participated in the study. After completing a background section, participants were randomly allocated into one of the experimental conditions (hearing one of four versions of a well-known song: a control version with piano and no singing, amateur singing, professional plain singing, and professional singing in the style of reality television singing). Participants were then asked to judge the performance they heard and to respond to items concerning their singing self-concept (including singing ability). RESULTS AND CONCLUSIONS: A series of ANCOVAs was used to examine the impact of the experimental condition on the participants' performance judgments and singing self-concept. The amateur singing was judged as the lowest quality. While there was no significant difference by experimental condition regarding possessing good singing ability, the experimental condition did affect people's singing aspirations and perceived ability to sing along with the performers. The pattern of results suggests that exposure to reality television-style singing may have negative impacts on people's singing self-concept via upward social comparison. Self-concept has been identified as an important predictor of musical engagement and participation and plays a role in motivating action. These results encourage music educators, singing voice pedagogues, and community musicians seeking to promote musical and singing participation to be aware of cultural influences on an individual's singing self-concept
Effect of casein genetic variants and glycosylation on bovine milk foaming properties
No full textThe effects of κ‐casein (κ‐CN) and β‐casein (β‐CN) genetic variant and κ‐CN glycosylation degree (GD, low or high) on interfacial and foaming properties of bovine skim milk were investigated. No significant effect was measured for milks with different ĸ‐CN and β‐CN genetic variants. However, milks of higher GD exhibited lower surface tension, enhanced foamability and differences in secondary protein structure compared to lower GD skim milks. Glycan attachment is believed to affect surface activity and the spread and packing of protein at the foam bubble liquid–air interface, leading to differences in foaming performance
Planners’ Changing Relationships With Participation: The Impact of New Training and Certification Schemes
No full textPublic participation is increasingly designed and facilitated by specially trained practitioners drawn from within the planning profession as well as outside of it. This shift is at least partially driven by the rise of new training and certification schemes. Drawing on exploratory interviews, and the example of the International Association for Public Participation in Canada and Australia, this paper highlights how these new forms of expertise are changing planners' relationships with public participation. Our research reveals several points of tension, including a bifurcation between planning and public participation professionals along with a consolidation around narrowed ideas of public participation
Australian urban designers’ experience of barriers and enablers to climate change action
No full textUrban designers have considerable potential to take important climate change actions in the built environment. Based on interviews with urban designers across Australia, it was found that the main actions taken were: development and use of policies and strategies; education and research; appropriate project designs; reduction of carbon footprints; advocacy and lobbying; the use of sustainability measures and ratings; and taking on projects oriented to climate change action. Key facilitators of these actions that overcame barriers were strong leadership, establishment of targets and measures, effective regulation, financial and other incentives, and access to trustworthy, practical information
Differential Intervention Outcomes Among Fathers Who Commit Domestic and Family Violence: The Influence of Parental Relationship Status
No full textAbstract
Background
In Western contexts, the behavior of domestically violent men is largely addressed through legal sanctions and standardised men’s behavior change programs. When domestically violent fathers remain together or in contact with their families, safety is an ongoing concern. However, program evaluations have failed to provide clear evidence for their effectiveness in addressing family violence in relation to parenting status. Part of the problem in developing efficacious programs has been the challenge of targeting them to typologies or socio-cultural needs of participants.
Purpose
The Caring Dads (CD) program supports father-change through leveraging men’s motivation to be positive parents, promoting child-centred fathering and cessation of family abuse. The aim of this study was to investigate whether participating fathers improved their co-parenting interactions, family functioning and wellbeing, and considered father characteristics and relationship statuses that coincided with positive outcomes.
Methods
This mixed method Australian study investigating a CD pilot incorporated psychological measures and semi-structured interviews at pre-, post- and 10 months post-intervention. Participants were fathers who attended CD in South-East Queensland, 2017–2019, and their co-parents.
Results
All fathers experienced improvements in parenting and family functioning by post-intervention, with greatest improvements for partnered fathers’ families. Partnered fathers also experienced improved parental alliance, unlike most separated fathers, although results must be viewed with caution due to small sample size and attrition across the study duration.
Conclusion
This study provides early support for improvements in CD participants’ fathering, parental alliance, and family functioning, most substantially for partnered fathers, though findings should be further investigated with larger cohorts
Forming brown commons through queer joy in butiki/baboy: A pride conversation series
No full textIn June 2023, Bangkô collective and Tambay Times Kids mobilized Filipino cis-heterosexual women and LGBTQ+ individuals to converse in a gathering which they called Butiki/Baboy: A Pride Conversation Series. Butiki/Baboy (literally Lizard/Pig) references a Filipino nursery song that goes “girl, boy, bakla, tomboy, butiki, baboy,” where butiki and baboy pertain to the made-inhuman others—those who are gender nonconforming and do not fit “Westernised” beauty standards. Conceived to discuss mundane queer topics that are the excess of relevant subjects highlighted during Pride Month, the 2023 iterations of Butiki/Baboy held at multiple sites around Los Baños, Laguna in the Philippines included sessions that revolved around narratives of queer intimacies of community development workers, queerbaiting on social media, radical joys in the mundanity of unfinished projects, and messy ecologies formed in the wilderness. This essay is interested in unpacking and understanding how queer joy emanates from this gathering of cisheterosexual women and LGBTQ+ individuals who are primarily cultural and creative workers, artists, and community development workers. It asks how queer joy, through Butiki/Baboy, affords moments of commoning. Taking the cue from José Esteban Muñoz who explains that the multifarious yet shared experience of suffering and hriving forms brown commons, I argue that Butiki/Baboy facilitated a space for engendering queer joy—that thing that is being banished from queer communities by an interlocking web of powers that tags queer bodies as unworthy and inhuman
Stretching spatial theories in comparative education: new approaches for challenging times
No full textThe aim of this article is to stretch spatial theorising in the field of comparative education. Among the different spatial theoretical approaches that have been explored in educational research in the last 10 years, we review social topology, spatial-temporalities, and beyond-human spatialities and how they have been used in comparative education research. To illustrate the potential of these approaches we then use them to analyse recent technological changes, shifts in governance, the impacts of global crises and the complicated ways in which they are spatially related to education. Through our analysis, we argue that comparative education research would benefit from making space for spatial theorising in relation to time, materiality, and the beyond-human, not only to better understand the world, but also to consider how education is ethically linked to the existential challenges humanity is facing today