Acıbadem Üniversitesi Açık Erişim Sistemi
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The Association Between Obesity, Being Overweight and Socio-economic Status Among School-Age Children Living in Big Cities
No full textIntroduction: Obesity has become a serious health concern worldwide. Risk factors of obesity are different in urban and rural areas. The aim of this study was to determine the risk factors related to obesity and being overweight among children in low and high socio-economic groups in a big metropolitan city, Istanbul. Materials and Methods: A cross-sectional study was carried out on 490 school-age children between 5 and 15 years. Low and high socio-economic groups were determined according to socio-economic status (SES). Socio-demographic characteristics of children were collected from the parents. Results: The effect of having frequent snacks rich in carbonhydrates (p=0,001) and sedentary lifestyles (p=0,001) on BMI was significant in both SES groups. In high SES group, BMI of the <10 years boys was significantly higher than that of the <10 years girlsBoys also had higher BMI at both age groups of either younger or older than 10 years. In low SES group, girls were significantly more overweight than boys. High family income, high paternal BMI and consuming energy rich products increased the obesity risk in children 1,560 times (OR: 1,560, \%95 CI: 1,046-2,326), 2,015 times (OR: 2,015, \%95 CI: 1,092-3,720), and 4,33 times (OR: 4,330, \%95 CI: 2,897-6,472), respectively. Conclusions: As conclusion, high family income, high paternal BMI and consuming energy rich products incre-ased the obesity risk. We suggest that every community has own characteristics but boys tend to have high BMIs in families with high SES.1APR76-831
The Results of Cardiac Surgery in Terms of Patient Blood Management in Turkiye Yuksek Ihtisas Training and Research Hospital
No full text1FEB83-844
Design and characterization of hydrogel models containing NK-92 or HEK293T cells for skin tissue engineering
No full text
Duchenne musküler distrofili mdx farelerde yüzme egzersizi, düşük dereceli lazer veya kombinasyonlarının dejenerasyon, inflamasyon oksidatif stres ve utrofin proteini ile irisin peptiti üzerine olan etkisi
No full textComparison of early and on-demand maternal feeding after Caesarean delivery: a prospective randomised trial
No full textINTRODUCTION This study aimed to compare early and on-demand maternal feeding after Caesarean delivery in terms of gastrointestinal complaints and patient satisfaction. METHODS A total of 262 women with uncomplicated singleton term pregnancies who underwent a Caesarean section under regional anaesthesia were randomised to a soft food diet served at Postoperative Hour 2 (early feeding group) or eating whenever they wanted to upon return to the ward (on-demand group). Patient satisfaction scores at the time of discharge and gastrointestinal complaints were compared. RESULTS The fed-early group comprised 133 (50.8\%) women and the on-demand group comprised 129 (49.2\%) women. Major characteristics and surgical procedures were comparable between the two groups. No significant between-group differences in demographic criteria or surgical procedures were evident (p > 0.05). The mean time to the first feeding was 120.00 +/- 00.00 minutes for the early feeding group as compared to 236.59 +/- 107.74 minutes for the on-demand feeding group (p = 0.001). Satisfaction levels did not differ significantly between the two groups (p = 0.366). Duration to first breastfeeding, analgesia on the ward, passage of flatus, defecation, mobilisation and urination after catheter removal did not differ significantly between the two groups (p > 0.05). CONCLUSION Early initiation of solid food in low-risk women after Caesarean delivery under regional anaesthesia was associated with high satisfaction and did not increase gastrointestinal complaints. We suggest having10OCT542-5456
Robot-assisted mitral valve surgery without aortic cross-clamping: An alternative technique
No full text3JUL415-4162
The importance of histological patterns on PD-L1 staining heterogeneity: Should we use pattern-based approach for selecting tumor samples for PD-L1 testing in lung
No full textBackground/aim: Programmed death ligand-1 (PD-L1) is a predictive marker for immunotherapeutic agents. However, heterogeneous staining of PD-L1 can cause false-negative results. The aim of this study is to evaluate the importance of histological patterns on PD-L1 staining heterogeneity in lung adenocarcinomas (LAC). Materials and methods: PD-L1 immunohistochemistry (IHC) stain was performed to two different tissue cores of 128 LAC cases, and cut-off values are given for grouping the cases according to the percentage of staining (1\%-10\%, 11\%-49\%, 50\%-100\%). Staining rates between cores were compared and analyzed by their histological patterns. Also, the relation of the PD-L1 expression with the clinicopathological characteristics of the cases was analyzed. Results: Overall, PD-L1 expression was observed in 53 of 128 cases (41.4\%, 1\% cut-off), 23.5\% of them were positive at 10\% cut-off and 14.1\% at 50\% cut-off. PD-L1 expression was significantly related to the high grade micropapillary and solid patterns of adenocarcinomas (p:0.01). Staining cut-offs were mostly similar between cores (43/50, 86\%) (k:0.843). However, 14\% of them were positive only in one core (7 of 50). This false negativity was mostly related to the histological patterns. Conclusion: Our data reveal the heterogeneous staining of PD-L1 expression, also micropapillary and solid patterns show higher rates of PDL expression. Therewithal, these findings also highlight the importance of taking into consideration of histological patterns, when choosing a paraffin block for the PDL1.1204-2135
Reverse total shoulder arthroplasty for failed treatment of proximal humerus fractures
No full textObjective: The aim of this study was to evaluate the functional and radiological outcomes and complications of reverse total shoulder arthroplasty (RTSA) for failed treatment of proximal humerus fractures (FTPHF). Methods: In this retrospective study, 20 patients (17 female, 3 malemean age = 71.35 yearsage range = 54-81 years) who underwent RTSA for FTPHF between 2012 and 2018 were included. The mean follow-up was 37.85 (range: 24-83) months. Outcome measures included shoulder range of motion, Constant score, ASES (American Shoulder and Elbow Surgeons) score, visual analog scale (VAS). Intra-or post-operative complications were also recorded. Results: The mean anterior flexion and external rotation improved from 37.25 degrees +/- 10.59 degrees and 11.05 degrees +/- 4.79 degrees preoperatively to 105.53 degrees +/- 9.33 and 22.37 degrees +/- 4.12 degrees postoperatively, respectively (P < 0.01 for both). The mean Constant and ASES scores ameliorated from 21.95 +/- 3.57 and 18.15 +/- 4.69 preoperatively to 61.7 +/- 7.6 and 71.18 +/- 4.69 at the final follow-up, respectively (P < 0.01 for both). VAS significantly reduced from 6.83 +/- 2.04 preoperatively to 1.79 +/- 0.61 at the final follow-up (P < 0.01). None of the patients had major complications or required revision. Conclusion: Treatment with the RTSA for the FTPHF seems to be an effective treatment method that can provide satisfactory radiological and functional outcomes with low complication rates.6NOV480-4855