AXSIS - Akademik ve Açık Erişim Bilgi Sistemi (Univ. KTO Karatay)
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Auditory Brainstem Response Findings in Incomplete Partition Malformations: Preliminary Results
No full textIntroduction: Inner ear malformations (IEM) account for about 20% of congenital hearing loss cases. Incomplete Partition (IP) malformations, which have normal external dimensions but abnormal internal cochlear structure, are the most common subgroup of IEM. Auditory brainstem response (ABR) is a crucial diagnostic tool for assessing IP anomalies (IP-I, IP-II, IP-III). Aim: The aim of this study was to evaluate ABR findings according to subgroups of IP anomalies. Material and methods: The study included individuals who were followed up in Hacettepe University Faculty of Medicine, Department of Otorhinolaryngology, diagnosed with IP malformation on radiologic imaging and underwent ABR 52 evaluation. Participants were evaluated on an ear basis, with 8 ears having IP-I, 30 ears with IP-II, and 3 ears with IP-III included in the study. ABR findings were analyzed statistically. Results: Participants’ ages ranged from 2.5 months to 8 years. In IP-I ears, wave V wasn’t observed at 99 dB nHL, and cochlear microphonics (CM) were seen in one ear at 2.5 ms. In IP-II, wave V was recorded in 56.67% of ears, with thresholds ranging from 40 to 99 dB nHL (mean: 69.65 ± 14.78 dB nHL). CM were not detected in IP-III, ABR was obtained in all of IP-III cases, with wave V threshold at 73.33 ± 6.24 dB nHL and latency of 7.43 ± 0.54 ms. Conclusions: Preliminary results revealed varying ABR outcomes across IP malformation subgroups. The absence of ABR in IP-I ears suggests poorer auditory outcomes, while the IP-II group showed highly variable results. These findings will enhance the literature and aid in clinical understanding of ABR outcomes in these anomalies
Is the Endocannabinoid System the New Hope in Cancer?
No full textThe term “cannabinoid” was originally defined as a group of aromatic hydrocarbon compounds found in the Cannabis sativa (Cannabis) plant (Mechoulam, 2019; Topuz, 2018). Cannabinoids can be categorized into three main classes: phytocannabinoids (found in the Cannabis plant), endocannabinoids (naturally produced in the body) and synthetic cannabinoids (produced in the laboratory). Cannabis plants have been used as a recreational drug since ancient times. The medicinal use of this plant dates back as far as 2700 BC (Mechoulam, 2019; Topuz, 2018). Its role in traditional Chinese medicine contributed to its inclusion in one of the earliest known pharmacopoeias. Nevertheless, the 20th century marked a significant shift in the history of Cannabis, as the extraction of cannabis from hemp led to both limitations on cultivation and restricted usage. Currently, cannabis stands as the most commonly consumed illicit substance worldwide. Persistent and frequent use of cannabis has been linked to cognitive impairments, declining academic performance, loss of motivation, dependency, and mental health issues such as psychosis, schizophrenia, and mood disorders. Conversely, recent studies indicate that cannabis-based medications may hold therapeutic promise for various medical conditions, particularly neurological and psychiatric disorders. These discoveries have prompted the legalization of medical cannabis in some states within the US and certain European nations (Aldemir et al., 2020). However, the use of phytoand synthetic cannabinoids in modern medicine is controversial due to their serious neuropsychiatric side effects (Sakin et al., 2015). Although the area of research on these cannabinoids remains highly controversial, it has been suggested that several phytocannabinoids (particularly the cannabidiol compound) may provide potential therapeutic benefits in conditions such as inflammation, cancer, addiction and epilepsy (Izzo, Borrelli, Capasso, Di Marzo, & Mechoulam, 2009; Patil, Goyal, Sharma, Patil, & Ojha, 2015)
Makine Öğrenmesi Modelleri İle Lamine Ahşap Kirişlerin Eğilme Dayanımı (MOR) Değerlerinin Tahmini
No full textBu çalışma, farklı geometrilere ve üretim parametrelerine sahip yapıştırılmış lamine ahşap
(glulam) kirişlerin eğilme dayanımı (MOR) değerlerinin üç noktalı ve dört noktalı eğilme testleri
üzerinden belirlenmesini ve bu değerlerin makine öğrenmesi tabanlı modeller kullanılarak
tahmin edilmesini amaçlamaktadır. Deneysel kirişler, PVAc-D3 (Polivinil Asetat) tutkallı
sarıçam (Pinus sylvestris L.) lameller kullanılarak düz, eğrisel, kontrplak takviyeli ve takviyesiz
olmak üzere dört farklı grupta üretilmiştir. Elde edilen deneysel veriler, beş farklı regresyon
algoritması (SVR, Lasso, Ridge, Huber ve XGBoost) ile analiz edilmiş ve her modelin tahmin
performansı 10 katlı çapraz doğrulama yöntemiyle değerlendirilmiştir. Analiz sonuçlarına göre
SVR modeli, üç noktalı eğilme deneylerinde R² = 0,9920 ve RMSE = 0,4587 MPa gibi oldukça
yüksek doğruluk ve düşük hata değerleriyle en başarılı performansı göstermiştir. Dört noktalı
deneylerinde de benzer bir eğilim gözlenmiş, SVR modeli R² = 0,9782 ile üstün performansını
korumuştur. Bu bulgular, makine öğrenmesi tabanlı yaklaşımların, glulam kirişlerin mekanik
özelliklerinin tahmininde deneysel testleri destekleyen güçlü bir mühendislik aracı olabileceğini
ortaya koymaktadır
Measurement of ω Meson Production in pp and p-Pb Collisions at √sNN=5.02 TeV
No full textWe present the measurement of the p(T)-differential production cross section of omega mesons in pp and p-Pb collisions at root s(NN) = 5.02 TeV at midrapidity by ALICE. In addition, the first measurement of the nuclear modification factor R-pPb for omega mesons at LHC energies is presented, complementing the existing measurements of lighter neutral mesons such as the pi(0) and eta. Within the measured p(T) range, the R-pPb of omega mesons is compatible with no cold nuclear matter effects within the uncertainties, consistent with previous measurements at lower energies. The omega/pi(0) ratio is presented for both collision systems, showing no collision system dependence within the uncertainties. The comparison to previously published omega/pi(0) ratios at lower and higher collision energies in pp collisions suggests a decreasing trend of the ratio above p(T) = 4 GeV/c with increasing collision energy. The data in both collision systems are compared to predictions from PYTHIA 8, EPOS LHC, and DPMJET event generators, revealing significant shortcomings in these models' ability to describe the production of omega mesons
Ethical Sensitivity and Perceived Clinical Decision-Making Competence Among Nursing Students: A Descriptive and Correlational Study
No full textAim: This study aimed to examine the relationship between ethical sensitivity and perceived clinical decision-making competence among nursing students. Background: Demonstrating ethical sensitivity in the perceived clinical decision-making competence is important for nursing students. During the pre-graduation period, students are expected to develop competence in making decisions based on ethical principles in clinical practice. Design: This study employed a descriptive and correlational design. Methods: Data were collected using self-reported online questionnaire. The study included 256 nursing students. Data were collected using the “Sociodemographic Questionnaire,” the “Ethical Sensitivity Scale Adapted for Nursing Students,” and the “Clinical Decision-Making in Nursing Scale.” Results: The mean total score for ethical sensitivity was 147.30 ± 15.34 (scale range: 30–210) and the mean total score for perceived clinical decision-making competence was 134.06 ± 29.44 (scale range: 40–200). A moderate positive correlation was found between ethical sensitivity and perceived clinical decision-making competence among nursing students (r = 0.399, p < .001). Furthermore, simple linear regression analysis revealed that students’ level of ethical sensitivity significantly predicted their perceived clinical decision-making competence (F = 15.860, p < .001). Conclusions: Nursing students’ ethical sensitivity and perceived clinical decision-making competence scores were above the midpoints of their respective scales, suggesting a relatively high level of ethical sensitivity and moderate-to-high perceived clinical decision-making competence. These findings indicate that higher ethical sensitivity positively influences nursing students’ perceived clinical decision-making competence. © 2025 Elsevier Lt
Comparative Retrospective Analysis of Magnetic Field Therapy and Extracorporeal Shock Wave Therapy in Pain Management for Heel Spur
No full textBackground: Heel spurs, caused by inflammation and overstretching of the plantar fascia, are a common source of heel pain. Although various conservative and invasive treatments are used, evidence on their effectiveness remains limited. Objective: This study aims to evaluate the effect of extracorporeal shock wave therapy (ESWT) and magnetic field application on pain levels in heel spur patients. Methods: The files of 80 patients diagnosed with heel spurs were accessed. Patients with missing demographic information in the files, incomplete Visual Analogue Scale (VAS) values, and patients with heel pain complaints for less than 5 months were excluded from the study. A total of 39 patients who met the study criteria were included in the study. While ESWT was applied to 21 of these patients (ESWT group), magnetic field was applied to 18 patients (MA group). All patients were given plantar fascia stretching exercises as a home program. Pain scores before and after treatment were evaluated with VAS. Results: A significant decrease was found in VAS values after the 5th session and 2 months later in both the ESWT group and the magnetic field group (p 0.05). Conclusion: It was observed that the pain of the patients decreased in both the early and late periods in both applications. © The Author(s) 202
Factors Associated With Pregnant Women's Perceived Stress and Coping Styles After the Devastating Earthquake in Turkey
No full textObjectives This study aims to determine the factors associated with pregnant women's perceived stress and coping styles after the devastating earthquake in Turkey. Methods This descriptive and cross-sectional study was conducted with 419 pregnant women between March 15 and May 15, 2023. Data were collected through the Personal Information Form, the Perceived Stress Scale, and the Coping with Earthquake Stress Scale. Results In this study, while the variables of employment status (P = 0.045) and number of pregnancies (P = 0.004) affected perceived stress, the variables of age (P = 0.049), income status (P = 0.003), place of residence (P = 0.036), and employment status (P = 0.001) were found to affect coping skills with earthquake stress. The Religious Coping sub-scale was a predictive factor on perceived stress (P = 0.002). In addition, a negative and linear relationship was found between the mean total score of the Perceived Stress Scale, the Religious Coping (P = 0.006, r = -0.134), Positive Reappraisal (P = 0.031, r = -0.106), and the total score of Coping with Earthquake Stress Scale (P = 0.005, r = -0.135). Conclusions This study found that there were some factors affecting the perceived stress and coping strategies of women after the earthquake, and the pregnant women used coping skills more as their perceived stress decreased; especially, they used religious coping and positive reappraisal strategies more. © The Author(s), 2025. Published by Cambridge University Press on behalf of Society for Disaster Medicine and Public Health, Inc
Comprehensive Evaluation of a Gas Turbine-Based Multi-Generation System for Power, Heating, Cooling, Freshwater, Hydrogen and Ammonia: 4E Assessment and Multi-Objective Optimization With RSM Desirability Approach
No full textIn this study, the production of power, heating, cooling, freshwater, hydrogen and ammonia in a gas turbine cycle (GTC)-based multi-energy system is analysed. From parametric study with energy, exergy, economic, environmental and exergo-enviro analyses, regression models were created for five different responses depending on the decision parameters. These are exergy efficiency (ηex), dynamic payback period (DPP-year), CO2 footprint (kg/kWh), net present value (NPV-/GJ). With these response values, bi-objective (BO), tri-objective (TO) and multi-objective optimization (MOO) studies including all responses were performed with Response Surface Method (RSM) and desirability function approach under various scenarios. In this context, RSM desirability plots and scores were generated by analyzing all binary (C(5,2)) and ternary C(5,3)) combinations of five different responses and MOO. As a result, a high desirability score of 0.8584 was obtained in MOO and an improvement of 2.19, 22.44, 1.37, 11.41 and 8.82 % was achieved for ηex, DPP-year, CO2 footprint-kg/kWh, NPV-/GJ, respectively compared to the base case. Based on all response values pertaining to the energy, exergy, economic, environmental performance of the multi-energy system with RSM optimization, a performance enhancement of 9.25 % was determined. © 2025 Elsevier Lt
Investigation of Psychiatric Nurses’ Views on Psychotherapy Implementation Processes: A Qualitative Study
No full textBackground: The views of psychiatric nurses on the practice of psychotherapy are multifaceted and profoundly influenced by their professional experience, educational background, and the therapeutic environment in which they work. This study aims to describe the views of psychiatric nurses regarding their psychotherapy implementation processes. Methods: A descriptive phenomenological design, one of the qualitative research methods, was adopted. The study sample consisted of 37 psychiatric nurses working in inpatient psychiatric units of hospitals in Türkiye. Data collection process was carried out through semi-structured, in-depth individual interviews. Participants were selected using the maximum variation sampling method. The data obtained were analyzed using thematic analysis. Results: As a result of the thematic analysis, three main themes and twenty-nine sub-themes were identified. Among the factors facilitating psychiatric nurses’ psychotherapy implementation processes, participants emphasized long-term patient interaction, patient observation skills, and the holistic perspective of psychiatric nurses. However, they indicated that excessive workload, insufficient nursing staff, perceived lack of support, and acute clinical processes were among the inhibiting factors. Participants also made recommendations regarding the need to expand psychotherapy training, increase awareness, strengthen professional support mechanisms, and update legal regulations. Conclusion: This study highlights both the enablers and barriers to psychotherapy implementation by psychiatric nurses in Türkiye. While prolonged patient interaction and observation skills facilitate practice, excessive workload, limited staffing, and lack of legal recognition hinder it. To advance psychotherapy in nursing, practice-based training programs, institutional support mechanisms, and regulatory updates are essential. These steps can empower nurses to provide psychotherapeutic care and enhance mental health service delivery. Clinical trial number: Not applicable. © The Author(s) 2025
The Meaning That Pediatric Nurses Attribute to Their Profession: A Phenomenological-Hermeneutic Study
No full textPurpose: To identify the meaning pediatric nurses assign to their profession, what they see as being a pediatric nurse, and the positive aspects and challenges of working as a pediatric nurse. Materials and methods: This phenomenological-hermeneutic study involved 20 nurses working in pediatric clinics between January and April 2023. The maximum variation sampling method, which is a type of purposeful sampling, was used in the study. The “Personal Information Form” and “Semi-Structured Interview Form” created by the researchers were used to collect data for this study, for which ethics committee approval was obtained beforehand. In-depth individual interviews lasting approximately 30–45 min were conducted with pediatric nurses online via Zoom. Results: Five themes were identified: factors that make care difficult, factors that make care easier, pediatric nurses' professional identity and strengths, values and approaches in childcare, and differences between pediatric and adult patients. Conclusion: The study determined that pediatric nurses love their profession and are joyful when working with children. However, in interviews with pediatric nurses, nurses stated that factors related to children, parents, the nature of pediatric nursing, and the team affect the care they provide to children. Providing team support to pediatric nurses and fostering feelings of appreciation can make them feel valued and competent. Practice implications: The results of this study can be used to empower nurses, especially in pediatric care, and to help improve the factors that influence care. © 2025 Elsevier Inc