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THE EFFECT OF R&D ACTIVITIES ON FINANCIAL PERFORMANCE IN THE FIRMS OF THE REAL SECTOR: EVIDENCE FROM TURKEY
No full textIn recent years, the increasing effect of globalization and its result of high competition environment, constantly the increasing consumer demands and technological developments lead companies to make innovation. In a highly competitive environment, the companies increase their R&D activities to respond to consumer demands and to achieve the targets of the companies. The effect of these activities on the financial performance of the firms is generally considered as a positive effect. However, these activities have a cost for the firm which constitutes a risk. Therefore, the effects of R&D activities on companies can be different. In this context, the aim of the study is to determine the relationship between financial performance and R&D activities in the companies operating in the real sector, taking into account the scale of the firm. For this purpose, the data of the firms of the real sector during the period between 2010 and 2020 has been analyzed with the Two-Step System Generalized Moments Method (GMM).According to the obtained findings; There is a negative relationship between R&D intensity and financial performance in micro- sized firms. However, this relationship positively changes in small and medium-sized firms. As far as general analyzes are concerned, without scale effect, R&D activities have a positive effect on financial performance in the companies of the real sector
Unutulmaya Yüz Tutmuş Yöresel Amasya Yemeklerinin Duyusal Analizle Değerlendirilmesi
No full textThe main purpose of this study is to evaluate the characteristic features of these local flavors and to contribute to the conservation efforts in the future by making a sensory analysis of the forgotten foods specific to the Amasya region. In line with this purpose, sensory analyses of the forgotten foods of Amasya, such as pastırmalı kuşekmeği, kabak kabuğu kavurması, soğan mıhlaması, mayasız and hamursuz foods were made. Sensory characteristics such as flavor, texture, smell and appearance constitute the focus of this analysis. The research has an experimental design and the data were collected using the sensory analysis technique. Sensory analyzes of the meals were made using the scoring test. The results of the local Amasya foods, which have sunk into oblivion, were evaluated by taking the arithmetic averages of the scores indicated by the panelists in the sensory analysis scale. Based on the results of sensory analysis, it is seen that mayasız food stands out in terms of appearance, taste and general taste among the local foods of Amasya, which has sunk into oblivion.Amasya yöresine özgü unutulmaya yüz tutmuş yemeklerin duyusal analizini yaparak, bu yöresel lezzetlerin karakteristik özelliklerini değerlendirmek ve gelecekte koruma çabalarına katkı sağlamak bu çalışmanın temel amacıdır. Bu amaç doğrultusunda, Amasya'nın unutulmaya yüz tutmuş yemeklerinden pastırmalı kuşekmeği, kabak kabuğu kavurması, soğan mıhlaması, mayasız ve hamursuz yemeklerinin duyusal analizleri yapılmıştır. Lezzet, doku, koku ve görünüş gibi duyusal özellikler bu analizin odak noktasını teşkil etmektedir. Araştırma deneysel tasarıma sahip olup veriler duyusal analiz tekniği kullanılarak toplanmıştır. Yemeklerin duyusal analizleri puanlama testi kullanılarak yapılmıştır. Duyusal analiz ölçeğinde panelistlerin belirtmiş olduğu puanların aritmetik ortalamaları alınarak unutulmaya yüz tutmuş yöresel Amasya yemeklerinin sonuçları değerlendirilmiştir. Duyusal analiz sonuçlarına dayalı olarak, mayasız yemeğinin unutulmaya yüz tutmuş Amasya yöresel yemekleri içerisinde görünüş, lezzet ve genel beğeni açısından ön plana çıktığı görülmektedir
A research on the relationship between religion and social media addiction in high school students (Example of Gaziantep-Şahinbey)
No full textBu araştırma ortaöğretim öğrencilerinin dindarlık ve internet kullanımı arasındaki ilişkinin incelenmesi amacıyla yapılmıştır. Bu araştırma, bilimsel araştırma yöntemlerine göre nicel bir araştırmadır. Araştırmada ilişkisel tarama yöntemi kullanılmıştır. Çalışmanın örneklemi Gaziantep ilinin Şahinbey ilçesinde bulunan lise öğrencileri oluşturmaktadır. Bu evren içinden basit tesadüfi örneklem yoluyla belirlenen dört farklı okul türünde (Fen lisesi, Anadolu Lisesi, Anadolu İmam Hatip Lisesi, Meslek Lisesi) toplamda 312 öğrenci örneklemimizi oluşturmaktadır. Bu ilk bölümünde din, dindarlık kavramları, dindarlık tipolojileri, gelişim dönemleri ve din arasındaki ilişki, sosyal medya ile ilgili teorik kavramlar açıklanmıştır. İkinci bölümde araştırma yöntemi, üçüncü bölümde yapılan araştırma sonucunda elde edilen bulgular açıklanmıştır.This research was conducted to examine the relationship between religiosity and internet use of secondary school students. This research is a quantitative research according to scientific research methods. Relational screening method was used in the research. The sample of the study consists of high school students in Şahinbey district of Gaziantep province. Our sample consists of a total of 312 students in four different school types (Science High School, Anatolian High School, Anatolian Imam Hatip High School, Vocational High School) determined by simple random sampling from this universe. In this first part, religion, concepts of religiosity, typologies of religiosity, the relationship between developmental periods and religion, and theoretical concepts related to social media are explained. In the second part, the research method and in the third part, the findings obtained as a result of the research are explained
Investigation of Impact of Vapor Pressure on Hybrid Streamflow Prediction Modeling
No full textIn this study, daily streamflow prediction models have been developed for Aksu Stream, in the Eastern Black Sea Basin of Turkey. To reach at this aim, hybrid artificial intelligence models have been developed, by using a new parameter, vapor pressure. Vapor pressure efficiency has been investigated for hybrid streamflow prediction models. Streamflow prediction models have been developed by using Artificial Neural Network (ANN), Multivariate Adaptive Regression Splines (MARS), and their hybrid models. Hybridization of streamflow prediction models has been made with Wavelet Transform (WT). 10 yearly daily hydrological (discharge (m(3)/s)), meteorological (precipitation (mm), vapor pressure (hPA)) data, and seasonality coefficient have been used as input data of streamflow prediction models. In the selection of the best streamflow prediction model, 14 different day-delayed input combinations have been established by using 10 yearly data. As a result of the study, the highest flow forecast performance model has been determined as Wavelet Artificial Neural Network (WANN) in the study area. In the WANN model, the vapor pressure parameter was found to reduce the error by about 18.5% and improve the forecast performance. This study has concluded that, vapor pressure may be used in the future studies as a new parameter for streamflow prediction models
Polarographic and Voltammetric Investigation of Heterocyclic Monoazo Compounds Azodicarboxylic Dimorpholide and 1,1'-Azodicarbonyl Dipiperidine
No full textThe electrochemical behaviours of azodicarboxylic dimorpholide (ADM) and 1,1 '-azodicarbonyl dipiperidine (ADP) have been investigated in Britton-Robinson (B-R) buffer solutions over a wide pH range (2.0-12.0) by means of some voltammetric and polarographic techniques. During the cathodic potential scan of ADM and ADP, a major signal for the reduction of -N=N- moiety was obtained. The effects of pH and scan rate on the cathodic signal were also studied. On the basis of voltammetric and polarographic data, an overall mechanism for the electrochemical reduction process of -N=N- moiety on both ADM and ADP molecules was postulated and discussed.Scientific Research Foundation of Ondokuz Mayis University, Turkey [PYO.FEN.1904.12.016]This study was financially supported by the Scientific Research Foundation of Ondokuz Mayis University, Turkey (project number: PYO.FEN.1904.12.016)
Effect of empagliflozin use on monocyte high-density lipoprotein ratio and plasma atherogenic index in obese and non-obese type 2 diabetic patients
No full textOBJECTIVE: Diabetes mellitus (DM) is a metabolic disorder marked by hyperglycemia, caused by impaired insulin secretion and activity. Chronic inflammation holds a significant role in the development, progression, and complications of DM and obesity. There are publications reporting that the monocyte/ high-density lipoprotein (HDL)-C ratio (MHR) and plasma atherogenic index (PAI) could be used as indicators of systemic inflammation. In the present study, we aimed to explore the effect of empagliflozin, an inhibitor of sodium -glucose co-transporter 2 (SGLT2), on MHR and PAI in obese and non-obese type 2 diabetes mellitus (T2DM) patients.PATIENTS AND METHODS: A total of 125 patients who presented to the outpatient clinics of Tokat Gaziosmanpasa University Hospital between January 2019 and January 2023 with a diagnosis of T2DM and were started on 25 mg empagliflozin and used for a minimum of 24 weeks were included in the study. The patients' age varied between 18-75 years, were without chronic liver disease, chronic renal failure, infection, or inflammatory disease, and were not on drugs affecting bone marrow. The patients were categorized into two groups, obese and non-obese, according to their body mass index (BMI). The data obtained were statistically analyzed using the IBM SPSS Statistics 25 software package.RESULTS: The mean age of the patients was 57.5 +/- 10.9 years. Of the patients, 59.2% (n = 74) were female, and 40.8% (n = 51) were male. The mean HbA1c percentage was 8.99 +/- 2.18% prior to empagliflozin treatment and significantly decreased to 7.68 +/- 1.80% after empagliflozin use (p < 0.05). The mean monocyte HDL-C ratio (MHR) pre-and post-empagliflozin treatment was 16.22 +/- 6.31 and 13.77 +/- 5.29, respectively, and these values significantly differed from each other (p < 0.05). The mean plasma atherogenic index (PAI) of the patients before empagliflozin treatment was 0.62 +/- 0.28, whereas, after the treatment, it significantly reduced to 0.52 +/- 0.27 (p < 0.05). While MHR and PAI statistically significantly de creased with the use of empagliflozin, there was no difference between the obese and non-obese patient groups in terms of MHR and PAI results.CONCLUSIONS: Studies in the literature show that the decrease in MHR and PAI leads to a decline in inflammation. MHR and PAI are inexpensive and practical markers to assess cardiovascular disease risk and inflammation in diabetic patients. This finding indicates that MHR and PAI can be used as inflammation markers in patients on empagliflozin treatment
Chronic kidney disease
No full textChronic kidney disease is one of the most common chronic diseases worldwide. In order to slow the progression of chronic kidney disease, cardiovascular risk factors should be controlled, albuminuria and the use of nephrotoxic drugs and herbal supplements should be avoided. © 2023 by Nova Science Publishers, Inc. All rights reserved
Çin Emperyalizminin Denizaşırı Kapitalist Adaları: Özel Ekonomik Bölgeler
No full textÇin emperyal gelenekten gelen bir ülke olarak küresel etki anlamında idareleri arasında süreklilik yaşayan bir ülkedir. Orta Çağ’dan itibaren Modern Çağ dahil benzer politikalar yürüten bir ülkedir. 1949 sonrası sosyalist devrimle birlikte bir dönem içeri kapansa da 1979 sonrası ekonomisini liberalleştirmiş ve serbest rekabetçi olmasa bile devlet kapitalizmi temelli bir ekonomiye sahip olmuştur. Bu bağlamda Çin, pazar ekonomisi temelli Özel Ekonomik Bölgeleri 1979 sonrası hızla kurmaya başlamıştır ve başlangıçta dört bölge olarak kurulan Özel Ekonomik Bölgelerin sayısı kısa sürede artmış ve deniz aşırı bir yapıya kavuşmuştur. Çin, bu Özel Ekonomik Bölgeleri bir ağ gibi tasarlamış ve tüm dünyaya özellikle çevre ülkelere yaymıştır. Bu durum Çin’in emperyalist vizyonuyla uyumludur. Çin, emperyal gelenekten gelip emperyalist bir yapıya dönüşmüştür. Çin emperyalizmini, modern emperyalist teorilerden ekonomi belirlenimli olarak, Michael Hardt ve Antonio Negri’nin İmparatorluk temelinde ve Manuel Castells’in ağ yaklaşımıyla açıklayabiliriz. Bu çalışmanın kapsamı, Özel Ekonomik Bölgeler bağlamında Çin emperyalizmidir. Çalışmanın önemi, Özel Ekonomik Bölgeleri Çin emperyalizmi çerçevesinde analiz etmektir. Çalışmanın kapsamı, 1980 sonrası ortaya çıkan Özel Ekonomik Bölgelerdir. Çalışmanın temel iddiası, Çin’in, Özel Ekonomik Bölgeler aracılığıyla çevre ülkeler üzerinde etki alanını arttırmak için emperyalist bir ağ kurmaya çalıştığı savunulabilir. Bu ağ aracılığıyla Çin hem küresel ekonomik yapıya eklemlenmektedir hem de siyasal anlamda hegemonya iddiası için gerekli gücü elinde toplamaktadır
Trabzon Ekmeği Ekşi Hamurlarının Bazı Fizikokimyasal ve Mikrobiyolojik Özellikleri
No full textSourdough bread is a traditional bread form produced in Türkiye using the fermentation method of lactic acid bacteria and molds. Through fermentation, the technological characteristics of sourdough bread are developed, resulting in the emergence of its characteristic taste and aroma. This process also inreases mineral bioavailability, extends shelf life and decreases glisemic index, making it highly desirable for consumers. As a result, the production of sourdough bread has become increasingly widespread. This study examines the physicochemical and microbiological characteristics of 54 samples of sourdough obtained from the Middle and Eastern Black Sea regions during summer and winter periods. It was determined that the pH values of the samples ranged from 3.30 to 5.43, and while the degree of acidity, total acidity, dry matter and ash contents ranges from 2.50 to 20.50, 0.23 to 1.79%, 49.05 to 65.91%, and 0.34 to 0.95%, respectively. The number of lactic acid bacteria (LAB), total aerobic mesophilic bacteria and molds of the sourdough samples were found to be in the range from 3.65 to 8.97 log CFU/g, 4.19 TO 7.20 log CFU/g and 4.17 to 7.52 log CFU/g, respectively. It was determined that the samples' acidity and pH levels had significant differences between regions, seasons and different bakeries. The number of microorganisms, dry matter and ash quantities of samples showed significant differences among bakeries in terms of these values. These results indicated a lack of standardization in the production of sourdough bread in the regions of the Middle and East Black Sea regions. © 2023 The Author(s)
A novel polyp segmentation approach using U-net with saliency-like feature fusion
No full textPolyps that pose a serious threat to human life, some of which are not detectable during a colonoscopy. This situation not only reduces the quality of life but also significantly raises healthcare costs. Polyp detection early reduces the risk of colorectal cancer and increases the likelihood of successful treatment. However, the complex environment of colonoscopic polyps, as well as various disturbing factors, make this process extremely difficult. Although advancements in computer-aided diagnosis systems have increased success in polyp detection tasks, there are still critical gaps today. In this study, a U-Net supported visual saliency approach is proposed to successfully determine polyp boundaries. Color space information, gradient information, and saliency are used as U-net input for this purpose. When compared to the original polyp images, the proposed end-to-end segmentation method has very high segmentation performance. Furthermore, its dice performance outperforms current state-of-the-art methods in the literature. © 2023 Elsevier Inc. All rights reserved