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    Review on Biological Management of Bactrocera Zonata Through Pathogenic Activity of Beauveria bassiana

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    Bactrocera zonata is the destructive pest of peach, mango, and banana by causing significant economic losses. It reduces fruit quality which directly causes decline in export of these economical fruits. Many management strategies were carried to suppress the population of this invasive pest. The use of chemical insecticides in the orchard for control of B. zonata is restricted because insecticides cause several complications in fruit health and makes fruits unfit for human consumption. Due these drawbacks of chemical control, Biological control strategies are preferred for better management of B. zonata. Entomopathogenic fungi are potential bio-control agent against many insect pests. The EPF (Beauveria bassiana) acts as potent bio-control agent. B. bassiana enriched with three cuticle degrading enzymes including protease, lipases and chitinases. These enzymes have ability to hydrolyze and degrade the epicuticle and break the antifungal proteins linkage present in that cuticle for facilitating the spore penetration. The current study emphasizes the activity of cuticle degrading enzymes (CDE) (protease, chitinase, lipases) of B. bassiana for the management of B. zonata

    Review on Exploring the Potential of Black Soldier Fly (Hermetia Illucens) as a Novel Feed Ingredient for Poultry

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    Poultry provides both direct and indirect employment opportunities to individuals. Every farm owner desires a reduced investment with more earnings. Over 50 % of the overall cost of chicken rearing is allocated to feed stuff. Among all feed ingredients, protein sources are the most expensive, yet protein is essential for production and growth. This exorbitant price cannot be sustained by the small-scale farmers. Consequently, contemporary scientists are attempting to substitute the protein supply with black soldier fly in their formulations. This review study examines the advantageous effect of utilizing Black Soldier Fly powder, larvae or oil, as demonstrated in scientific studies. Our data indicates that a significant number of individuals in this era have adopted Black Soldier Flies as a protein source, substituting it for traditional ration formulations to satisfy protein requirements. The larvae, powder, and oil of the black soldier flies directly influence poultry production and growth performance. In case of broiler chickens, these substitutions enhance their feed conversion ratio, carcass characteristics and meat quality. All scientists have demonstrated that the development of black soldier flies may utilize chicken dung and sheep-goat feces, hence facilitating waste management. The method of rearing and investment for Black Soldier Fly are significantly lower than the other sources of protein. We may aspire to a society where individuals are trusted and engage in the substitution of protein sources

    Anti-Cancer Effects of Soy Isoflavones against Cancer by Radiosensitizing Properties

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    Background: It is necessary to investigate the targets and pathways on which soy isoflavones act as radiosensitizers for their future use and their potential therapeutic effects. Objective: This systematic review aims to discuss and highlight future perspectives on the radiosensitizing effects of soy isoflavones against cancer cells. Methods: We thoroughly searched multiple databases, such as PubMed/MEDLINE, Cochrane Library, Web of Science, and Scopus. We aimed to find studies investigating the effectiveness of soy isoflavones in increasing the sensitivity of different types of cancer to radiation treatment. We extracted data according to the study\u27s aim, and the studies\u27 outcomes were reviewed. Results: The radiosensitizing effects of soy isoflavones are related to the accumulation of intracellular Reactive Oxygen Species (ROS), reducing Glutathione (GSH), Nuclear factor erythroid 2– related factor 2 (Nrf2) and Heme Oxygenase-1 (HO-1). They also induce cancer cell apoptosis through inhibited Nuclear factor kappa B (NF-κB), apurinic/apyrimidinic endonuclease 1/redox factor- 1 (APE1/Ref-1) and HIF-1α, upregulation of poly (ADP-ribose) polymerases (PARP) and improve cytochrome c, upregulation Bcl-2-associated X protein (Bax), inhibited B-cell lymphomaextra- large (Bcl-xL) and activation of caspase-3 and -8. Moreover, by inhibiting p21, increased phosphorylation of p53 and PARP-1-dependent ATP depletion caused DNA damage and impaired DNA repair. Soy isoflavones also arrest the cell cycle by interfering with the G2/M checkpoint. Conclusion: In vivo and in vitro studies indicated that soy isoflavones enhanced radiotherapy effects on cancer cells with protective effects on healthy cells. Also, clinical studies reported safe and satisfactory properties of soy isoflavones along with radiotherapy in cancer treatment

    Mitigating Perceived Overload of Communication Visibility: the Role of ESM policies

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    Purpose This study aims to explore how communication visibility affects employees’ work engagement from the negative perspective of employees’ perceived overload in the context of enterprise social media (ESM) and the role of ESM policies in the relationship between communication visibility and perceived overload. Design/methodology/approach This study examines how communication visibility (i.e. message transparency and network translucence) affects employees’ perceived overload (i.e. information overload and social overload), which in turn affects employees’ work engagement, and how ESM policies moderate the relationship between communication visibility and perceived overload. Partial least squares (PLS) analysis was conducted on data gathered from 224 ESM users in workplaces. Findings Communication visibility has significant positive impacts on perceived overload, perceived overload has significant negative impacts on work engagement and ESM policies negatively moderate the relationships between communication visibility and perceived overload, except for the relationship between message transparency and social overload. Practical implications The findings provide new insights for organizational managers to formulate ESM policies to mitigate perceived overload and guidance for ESM developers to improve ESM functions to alleviate perceived overload. Originality/value This study provides empirical evidence to explain the role of communication visibility and perceived overload in employees’ work engagement, which contributes to the existing literature on the negative impacts of communication visibility

    Analyzing Contributing Factors to Obesity Rates in Ohio

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    Obesity, along with its comorbidities, has been significantly increasing worldwide for the pastfew decades. Our objective in this report is to investigate several factors that may be contributingto obesity rates in Ohio, specifically physical inactivity, access to healthy foods, and living in arural/urban county. Using data from the Ohio County Health Rankings for 2016 and 2023, wewere able to analyze the differences in obesity rates between rural and urban Ohio counties(RQ1), compare how access to healthy foods have changed over time in Ohio (RQ2), determinewhether there is a correlation between obesity and access to healthy foods for Ohio counties(RQ4), and examine how access to healthy foods and physical inactivity rates predict obesityrates for Ohio counties (RQ5). Additionally, County Health Rankings from Indiana andCalifornia in 2023 were also used to analyze the difference between Ohio, Indiana, andCalifornia with regard to the physical inactivity rates for 2023 (RQ3). The results found that ruralcounties had significantly higher rates of obesity (38.81%) compared to urban counties (36.37%)in Ohio for the year 2023 (P=0.002). Additionally, limited access to healthy foods in Ohiosignificantly increased from 5.04% to 6.14% between the years 2016 and 2023 (P\u3c0.001).Physical inactivity was also found to be significantly decreased in California (21.47%) comparedto Ohio (27.24%) and Indiana (26.46%). Although there was no correlation found betweenaccess to healthy foods and obesity, physical inactivity was found to impact obesity rates in aregression analysis

    Using Dashboards to Support Continuous Quality Improvement in Undergraduate and Graduate Medical Education

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    Like other complex systems, medical education programs require a systematic continuous quality improvement (CQI) approach to drive effective improvement. Accreditation bodies in both undergraduate medical education (UME) and graduate medical education (GME) require programs to have effective CQI processes. Dashboards facilitate visualization and tracking of key metrics that impact medical education programming, thus driving excellence. Keys to developing useful dashboards include using existing program evaluation frameworks to identify desired outputs, determine acceptable evidence, and identify key data sources. In developing dashboards, it is important to consider data management including oversight and appropriate sharing of reports. When effectively developed and delivered to key parties, data dashboards serve as valuable tools to drive improvement of medical education programing. The purpose of this paper is to provide guidance for dashboard implementation and use in medical education, with a focus on UME and GME, based on available literature and experiences in our own institutions

    Postcard from Unknown to [Milton Wright], from California, USA (San Diego Mission)

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    An undated California postcard featuring the San Diego Mission. Collected by Milton Wright.https://corescholar.libraries.wright.edu/special_ms711_postcards/1056/thumbnail.jp

    Postcard from Unknown to Milton Wright, from California, USA (Mission Bells of San Gabriel)

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    An undated California postcard featuring the Mission Bells of San Gabriel. Collected by Milton Wright.https://corescholar.libraries.wright.edu/special_ms711_postcards/1054/thumbnail.jp

    Postcard from Unknown to [Milton Wright], from England (St. Georges Chapel Choir)

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    An undated postcard from England featuring St. Georges Chapel Choir in Windsor Castle. Collected by Milton Wright.https://corescholar.libraries.wright.edu/special_ms711_postcards/1077/thumbnail.jp

    Postcard from Unknown to [Milton Wright], from Dresden, Germany (Der Falschpieler)

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    An undated postcard from Dresden, Germany featuring the painting Die Falschspieler by artist Valentin de Boulogne, despite the incorrect description found on the back of the card. Collected by Milton Wright.https://corescholar.libraries.wright.edu/special_ms711_postcards/1094/thumbnail.jp

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