374472 research outputs found
Sort by
Biophysical studies of antiparallel clamps for targeting polypyrimidine sequences through triplex formation
No full textPeer reviewe
Oxidative and texture storage stability of HPMC sunflower oil oleogels prepared by different indirect approaches
No full textThe oxidative, thermal and texture stability during a four weeks storage period of hydroxypropyl methyl cellulose sunflower oil oleogels prepared by the emulsion template and foam template methodologies were studied and compared with a conventional shortening. The stability of 50/50 oleogel/shortening blends were also investigated. The results showed that the texture of the oleogels prepared by the emulsion template method became harder after four weeks (12.75 N.s to 77.08 N.s). The emulsion template oleogel blend with shortening showed a very similar texture than the pure shortening after four weeks storage (42.71 N.s and 39.61 N.s, respectively), whereas the texture of the oleogels prepared by the foam template method as well as their blends with shortening were softer (2.17 N.s and 4.76 N.s). The melting behaviour of emulsion-based oleogels with shortening blends was not affected by storage time. Oxidative stability showed that both foam-based oleogels and emulsion-based oleogel shortening blends have good oxidative stability. The above results indicate aproper storage stability of oleogels and oleogel/shortening blends as potential alternative to conventional plasticized fats.This work is supported by the Spanish Ministry of Science and Innovation (Funding number: PID2022-1375870B-C21). We also thank the financial support from the China Scholarship Council for Dr. Qi Wang. IATA-CSIC is a Centre of Excellence Severo Ochoa (CEX2021-001189-S funded by MCIN/AEI/10.13039/501100011033).With funding from the Spanish government through the ‘Severo Ochoa Centre of Excellence’ accreditation (CEX2021-001189-SPeer reviewe
Solid-state nanochannel arrays for the diagnosis of infections caused by Pseudomonas aeruginosa
No full textNovel gluten-free pasta made with purple corn: Nutritional, technological and sensorial quality
No full textGluten-free products, including pasta, are generally highly processed and low in antioxidant compounds, often with compromised organoleptic qualities. To overcome these limitations, a new gluten-free pasta was designed using purple corn, a variety rich in antioxidant polyphenols. Five pasta variations were developed—100 % wheat semolina, 100 % yellow corn, 90 % yellow corn+10 % rice flour, 100 % purple corn, and 90 % purple corn+10 % rice flour —and analyzed their chemical composition (particularly polyphenol content) as well as their physical, chemical, and sensory properties following extrusion and boiling. A number of new cyanidin and spermidine derivatives are reported for the first time in corn. Extrusion was effective in producing corn pasta, preserving polyphenol content and resulting in good physical and technological properties, whereas boiling reduced polyphenol levels by up to 80 % Sensonetrics analysis indicated some unwanted attributes associated with purple corn. Overall, purple corn pasta shows potential as a gluten-free alternative, rich in antioxidants and moderately resilient to production and cooking processes, though sensory attributes may require further optimization for higher consumer acceptance.This work was supported by the Spanish MCIN/AEI/10.13039/501100011033/ (Grant number PID2019-107009RB-100) and European Union‘s Erasmus + Programme (M.A.)Peer reviewe
The Post-periapsis Evolution of Galactic Center Source G1: The Second Case of a Resolved Tidal Interaction with a Supermassive Black Hole
Get PDFWe present new adaptive optics (AO) imaging and spectroscopic measurements of Galactic center source G1 from W. M. Keck Observatory. Our goal is to understand its nature and relationship to G2, which is the first example of a spatially resolved object interacting with a supermassive black hole (SMBH). Both objects have been monitored with AO for the past decade (2003-2014) and are comparatively close to the black hole (a ∼ 200-300 au) on very eccentric orbits (e ∼ 0.99; e ∼ 0.96). While G2 has been tracked before and during periapsis passage (T ∼ 2014.2), G1 has been followed since soon after emerging from periapsis (T ∼ 2001.3). Our observations of G1 double the previously reported observational time baseline, which improves its orbital parameter determinations. G1's orbital trajectory appears to be in the same plane as that of G2 but with a significantly different argument of periapsis (Δω = 21 ± 4°). This suggests that G1 is an independent object and not part of a gas stream containing G2, as has been proposed. Furthermore, we show for the first time that (1) G1 is extended in the epochs closest to periapsis along the direction of orbital motion, and (2) it becomes significantly smaller over time (450 au in 2004 to less than 170 au in 2009). Based on these observations, G1 appears to be the second example of an object tidally interacting with an SMBH. G1's existence 14 yr after periapsis, along with its compactness in epochs further from the time of periapsis, suggest that this source is stellar in nature. © 2017. The American Astronomical SocietySupport for this work was provided by NSF grants AST0909218 and AST-1412615, the Levine-Leichtman Family
Foundation, the Preston Family Graduate Fellowship (held by
B.N.S. and A.B.), and the UCLA Graduate Division Dissertation Year Fellowship (held by B.N.S). The W. M. Keck
Observatory is operated as a scientific partnership among the
California Institute of Technology, the University of California,
and the National Aeronautics and Space Administration. The
authors wish to recognize that the summit of Maunakea has
always held a very significant cultural role for the indigenous
Hawaiian community. We are most fortunate to have the
opportunity to observe from this mountain. The Observatory
was made possible by the generous financial support of the W.
M. Keck Foundation. B.N.S. also thanks James Larkin for his
engaging discussions about the nature of G1 and G2,
Alexander Stephan for his comments, and Ann-Marie Madigan
for her thoughts on G1. We thank Arezu Dehghanfar for help
with preparing the manuscript. We thank the anonymous
referee for providing fruitful comments
Manifestation of Rouse and Entanglement Dynamics in Non-Cross-Linked and Cross-Linked Polymers Studied by Field-Cycling and Multiple Quantum NMR
No full textRubbers prepared from technical poly(butadiene) and natural
poly(isoprene) are studied by field-cycling (FC) 1H NMR relaxometry to elucidate
the changes of the relaxation spectrum. Starting with the non-cross-linked polymer
successively cross-links are introduced via sulfur or peroxide vulcanization. Applying
an advanced home-built relaxometer allows one to probe entanglement dynamics in
addition to Rouse dynamics. We show that entanglement dynamics evidenced in
terms of a characteristic power-law in the NMR susceptibility is still observed with an
exponent identical to that in non-cross-linked linear polymers. Yet, the entanglement
regime disappears more and more from the accessible frequency window upon
increasing the cross-link density and a spectrally enlarged Rouse regime is revealed.
Adding a swelling agent, the manifestation of the Rouse and entanglement regimes
virtually does not change, yet, the apparent power-law exponents increase.
Concomitant multiple-quantum (MQ) 1H NMR experiments provide information
on the structure of the rubber network in terms of the residual dipolar coupling and the fraction of the network defects, i.e.,
persisting entangled or nonentangled chains, introduced upon cross-linking and swelling.The work was supported by the Deutsche Forschungsgemein-
schaft (DFG) through the grant RO/907-22. We appreciate
valuable comments by Nail Fatkullin. F.M.S. and J.L.V. thank
the Spanish Ministry of Science and Innovation (MINECO)
for the funding received under grants PID2020-119047RB-I00,
PLEC2021-007793 and PID2023-147542OB-I00.Peer reviewe
Microbiota intestinal y Autismo
No full textTrabajo fin de máster presentado en la Universidad Europea de Madrid, Máster en Microbiota, Probióticos y Prebiótico
Space and laboratory discovery of iminopentadienylidene, HNC5
No full text5 pages, 4 figures, 3 tablesWe report the discovery of HNC5 in TMC-1. Six lines have been found in harmonic relation, with quantum numbers J = 12 11 up to J = 17 16. The lines can be reproduced with the standard frequency relation for linear molecules with B = 1361.75034 ± 0.00033 MHz and D = 32.2 ± 0.7 Hz. The assignment of the carrier to iminopentadienylidene was achieved through examining the possible candidates at a high level of theoretical ab initio calculations. Motivated by the good agreement between the observed B and the calculated value for HNC5, we searched for it in the laboratory and observed the transitions J = 5 4 to 7 6. The derived rotational and distortion constants are 1361.74998 ± 0.00040 MHz and 26.5 ± 5.5 Hz, respectively. Hence, we solidly conclude that the carrier of the lines found in TMC-1 is HNC5. The calculated dipole moment for this species is 7.7 D and the derived column density is (1.3 ± 0.2)- 1010 cm 2. We used the new QUIJOTE data to improve previous observations of HC4NC and found that the abundance ratio HC4NC/HNC5 is 10 ± 2. The abundance ratio of HC5N and its two isomers HC4NC and HNC5 is 500 ± 80 and 5100 ± 800, respectively. These abundance ratios are higher by a factor of 10 than those of the equivalent isomers of HC3N. Chemical models reproduce the observed abundances reasonably well when a chemistry similar to that of the smaller species C3HN isomers is adopted. The formation of HNC5 and HC4NC arises from the dissociative recombination with electrons of the cations HC5NH+ and HC4NCH+.The present study was supported byMinistry of Science and Technology of Taiwan and Consejo Superior de Investigaciones Científicas for funding support under theMoST-CSIC MobilityAction2021 (Grant 11-2927-I-A49-502 andOSTW200006). R.F., C.C., M.A, and J.C. thankMinisterio de Ciencia e Innovación of Spain (MICIU) for funding support through projects PID2019-106110GB-I00, PID2019-107115GBC21/AEI/10.13039/501100011033, and PID2019-106235GB-I00. R.F., C.C., M.A, and J.C. also thank ERC for funding through grant ERC-2013-Syg 610256- 312NANOCOSMOS.Y.E. acknowledges Ministry of Science and Technology of 313Taiwan for MOST104-2113-M-009-202project
The EDGE-CALIFA Survey: Variations in the Molecular Gas Depletion Time in Local Galaxies
Get PDFWe present results from the EDGE survey, a spatially resolved CO(1-0) follow-up to CALIFA, an optical Integral Field Unit survey of local galaxies. By combining the data products of EDGE and CALIFA, we study the variation in molecular gas depletion time (¿dep) on kiloparsec scales in 52 galaxies. We divide each galaxy into two parts: The center, defined as the region within 0.1 R25, and the disk, defined as the region between 0.1 and 0.7 R25. We find that 14 galaxies show a shorter ¿dep (~1 Gyr) in the center relative to that in the disk (¿dep ~ 2.4 Gyr), which means the central region in those galaxies is more efficient at forming stars per unit molecular gas mass. This finding implies that the centers with shorter ¿dep resemble the intermediate regime between galactic disks and starburst galaxies. Furthermore, the central drop in ¿dep is correlated with a central increase in the stellar surface density, suggesting that a shorter ¿dep is associated with molecular gas compression by the stellar gravitational potential. We argue that varying the CO-To-H2 conversion factor only exaggerates the central drop of ¿dep. © 2017. The American Astronomical Society. All rights reserved.We thank the referee, Christine Wilson, for her valuable
input that greatly improved the manuscript. We also thank John
Carpenter for his help in managing the schedule of CARMA
observations and Christopher McKee for insightful discussion.
The works of D.U. and L.B. are supported by the National
Science Foundation (NSF) under grants AST-1140063 and
AST-1616924. A.D.B. and R.C.L. acknowledge support from
NSF through grants AST-1412419 and AST-1615960. A.D.B.
also acknowledges visiting support by the Alexander von
Humboldt Foundation. T.W. and Y.C. acknowledge support
from NSF through grants AST-1139950 and AST-1616199.
The work of ECO is supported by the NSF under grant AST1312006. S.F.S. acknowledges the PAPIIT-DGAPA-IA101217
project and CONACYT-IA-180125. R.G.B. acknowledges
support through grant AYA2016-77846-P. E.R. is supported
by a Discovery Grant from NSERC of Canada. S.V. acknowledges support from NSF AST-1615960.
We acknowledge the usage of the HyperLeda database
(http://leda.univ-lyon1.fr). Support for the CARMA construction was derived from the states of California, Illinois, and
Maryland, the James S. McDonnell Foundation, the Gordon
and Betty Moore Foundation, the Kenneth T. and Eileen L.
Norris Foundation, the University of Chicago, the Associates of
the California Institute of Technology, and NSF. This research
is based on observations collected at the Centro Astronomico
Hispano Aleman (CAHA) at Calar Alto, operated jointly by the
Max-Planck Institute for Astronomy (MPIA) and the Instituto
de Astrofisica de Andalucia (CSIC).
Software: Pipe3D (version 2.2; Sánchez et al. 2016),
MIRIAD (Sault et al. 1995), idl_mommaps.pro (Wong et al. 2013), linmix_err.pro (Kelly 2007), matplotlib (Hunter 2007),
and SciPy (Jones et al. 2001)
ATTENUATION OF LOW FREQUENCIES FOR DUCTED SYS-TEMS BASED ON THE ACOUSTIC BLACK HOLE TECHNIQUE
No full text30th International Congress on Sound and Vibration, 8 - 11 july, 2024, Amsterdam.
8 páginas, 5 figuras.The Acoustic Black Hole (ABH) is a new technique that was proposed for passive vibration control but has been recently extended for broadband noise control in ducted geometries. For instance, in areas such as building and transportation industries, the control of low-frequency noise propagating in exhaust or air-conditioning waveguides constitutes an important issue and a very challenging problem. Although many studies have presented closed ABH geometries, the used of open-ended ABHs is compulsory in duct systems where a mean axial flow is present. In this case, the concept of sound trapping involves minimization of both sound reflection and transmission inside the retarding structures. This work is focused on the optimal determination of the ABH physical constituting parameters that mostly influence the metamuffler performance. The requirements on minimal volume impose a constraint for the total dissipation that has to be considered regarding low-frequency broadband operation and manufacturing constraints. An analytical formulation will be presented in terms of the Transfer Matrix Method to model a widely-opened silencer composed of a finite number of sidebranch cavities with an axial variation of their depth according to an exponential law. These cavities are separated by rigid rings of constant thickness. Assuming plane wave propagation along the main duct and within the annular cavities, visco-thermal effects are considered to calculate the power dissipated by the ABH. Influence of several parameters is studied considering the optimal axial rate of cavity depth variation, the wall porosity and the ratio between the total silencer length and the duct radius. The simulated optimal results are verified against a set of measurements performed in a standing wave tube where the ABH is inserted. A good agreement is found between both values that validates the proposed metamuffler with near-unit dissipation over its efficiency broad bandwidth.This work is part of the project TED2021-130103B-I00, funded by
MCIN/AEI/10.13039/501100011033 and the European Union “NextGenerationEU”/PRTR, and project
PID2022-139414OB-I00 funded by MCIN/ AEI /10.13039/501100011033/ and by "ERDF A way of
making Europe". It has also received support from the French government under the France 2030 in-
vestment plan, as part of the Initiative d'Excellenced'Aix-Marseille Université - A*MIDEX (AMX-22-
RE-AB-157).Peer reviewe