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Unraveling dimensional tuning: From 2D to 3D in covalent organic frameworks for enhanced 2e- oxygen reduction reaction
No full textCovalent organic frameworks (COFs) with a two-dimensional (2D) topology have recently emerged as promising catalyst systems for the electrosynthesis of hydrogen peroxide (H2O2) from oxygen (O2). However, designing 2D catalysts to achieve higher H2O2 selectivity presents a significant challenge because of the extensive layer stacking and the aggregated active sites located in the basal planes. It results in lower atom utilization, which requires attention. In this study, we present two functionally similar COFs: one with a 2D rhombus topology (2D@BT_TPA-COF) and another with a three-dimensional (3D) noninterpenetrated pts topology (3D@BT_TPA-COF). Both COFs were utilized for the 2e– oxygen reduction reaction (2e– ORR). Tunning the dimensionality from 2D to 3D resulted in an increase in H2O2 selectivity from approximately ∼56% to approximately ∼96% (at 0.4 V) and a rise in the turnover frequency (TOF) from 0.05 to 0.08 s–1 at 0.3 V. Nonaggregated active site distribution over 3D topology, featuring higher active site exposure, provides better access to the O2/electrolyte and facilitates electron transfer leading to higher 2e– ORR activity and selectivity compared to the 2D counterpart.C.R.C. acknowledges the Center for Alkaline-based Energy Solutions (CABES), an Energy Frontier Research Center funded by the U.S. Department of Energy (DOE), Office of Science, Basic Energy Sciences (BES), under Award # DESC0019445. A.M. acknowledges the Spanish Ministry of science through the Ramon y Cajal program (RYC2018-024561-I) and to the Gobierno the Aragon (Nanomidas group, code E13_23R). A.M. also acknowledges the use of instrumentation as well as the technical advice provided by the National Facility ELECMI ICTS node “Laboratorio de Microscopías Avanzadas” at the University of Zaragoza. Z.C. acknowledges the Department of Energy, Office of Basic Energy Sciences, USA, under Award Number DE-SC0023418. Z.C. also thanks the computational support from the Center for Nanophase Materials Sciences (CNMS), a US Department of Energy Office of Science User Facility operated at Oak Ridge National Laboratory, and resources of the National Energy Research Scientific Computing Center (NERSC), a US Department of Energy Office of Science User Facility located at Lawrence Berkeley National Laboratory, operated under Contract no. DE-AC02-05CH11231 using NERSC award BES-ERCAP0027465. This research used the Proximal Probes Facility of the Center for Functional Nanomaterials (CFN), which is a U.S. Department of Energy Office of Science User Facility, at Brookhaven National Laboratory under Contract no. DE-SC0012704.Peer reviewe
Supporting Information: Unraveling dimensional tuning: From 2D to 3D in covalent organic frameworks for enhanced 2e- oxygen reduction reaction
No full textDetailed PXRD data with different reaction conditions; FTIR; BET plot; XPS plots; PXRD simulation information; and other electrochemical measurements.Peer reviewe
Aristófanes, Ecclesiazusae 918-926 en clave poética: léxico, sintaxis, poesía popular y reparto de papeles
No full textAristophanes, Ecclesiazusae 918-926 in a Poetic Key: Vocabulary, Syntax,
Popular Poetry and Distribution of Roles · Throughout the scene between the young
woman and the first old woman in Ecclesiazusae (893-937), before the appearance of
the young man, there are several passages in which either the meaning, or the distribution of roles, or both are discussed. We focus here on the lyric vv. 918-923 and
the following three trimeters (924-926), providing arguments for their assignment
to one character or another, through an in-depth analysis of the vocabulary and
syntax, in connection with the clearly popular character of the songs involved in
the entire scene. The words ὑφαρπάζεσθαι “appropiate”, “usurp”, παίγνια “light
songs”, “ditties” and the expression τὸν ἀπ’ Ἰωνίας τρόπον “in the Ionian style (of
song)” find their full meaning when understood in reference to the traditional lyric
song that the young woman performs from v. 911 on. The meaning of ὥραν … οὐδ’
ἀπολήψει (922-923) is also clarified, and the sentence οὐκ ἄν ποθ’ ὑφαρπάσαιο τἀμὰ
παίγνια (920 s.), traditionally seen as a potential assertion, could perhaps be understood as a polite order or request, here used ironically.Peer reviewe
Dataset for From Green to Black Gold: Highly Microporous Carbons from Pistachio Shells by a Controlled Physical Activation Process
No full textThese data are associated with the published work: ChemSusChem 2025, 18, e202401288: From Green to Black Gold: Highly Microporous Carbons from Pistachio Shells by a Controlled Physical Activation Process, by Ana Fernández-Lera,[a] María Dolores Casal,[a] Quentin Judalet,[b] Noel Díez,[a]
Teresa Valdés-Solís,[a] and Marta Sevilla*[a]This research was supported by the European Commission, Horizon Europe Framework Program, Call HORIZON-CL4-2021-RESILIENCE-01, Project MAST3RBOOST, GA 101058574.Peer reviewe
Art&Sea for social change, el programa de Arte y Ciencia del Instituto de Ciencias del Mar
No full textIV Jornadas de Cultura Científica y Ciencia Ciudadana del CSIC, 16-17 June 2025, MadridPeer reviewe
Education as a main driver of the circular and sustainable transition towards the future bioeconomy strategy
No full textParticipación en la mesa redonda del GenB and BioBeo EU projects, Bridging generations: Education and policy to shape a sustainable futurePeer reviewe
Incipient Range Expansion of Green Turtles in the Mediterranean
No full text16 pages, 4 figures, supporting information https://doi.org/10.1111/mec.17790.-- Data Availability Statement: 2bRAD raw data are available at the European Nucleotide Archive (ENA) under the project PRJEB70796In response to global climate change, numerous taxa are expanding their living ranges. In highly migratory species such as sea turtles, this expansion may be driven by individuals from nearby or distant areas. Recent nests outside the species' typical nesting range and reports of adult-sized individuals in the western Mediterranean suggest a green turtle (Chelonia mydas) range expansion into the central and western Mediterranean. To assess the green turtles' origin in these novel habitats, we built a genomic baseline using 2bRAD sequencing on five individuals from each of three Regional Management Units (RMUs): North Atlantic, South Atlantic and Mediterranean. We then compared this baseline with genotyped hatchlings from three nests laid in new central and eastern Mediterranean sites and four mature-sized green turtles tagged with satellite telemetry in the western Mediterranean. Our analyses revealed that the Tunisia nest originated from the South Atlantic RMU, while the Crete nests were produced by turtles from the Mediterranean RMU. Additionally, the three adult-sized turtles sampled in the southwestern Mediterranean were assigned to the South Atlantic RMU, while the mature-sized individual sampled in the northwestern Mediterranean belonged to the Mediterranean RMU. These results suggest a simultaneous incipient colonisation by two geographically distant RMUs. We propose that the range expansion of green turtles into the central and western Mediterranean is likely climate driven and these populations may become globally important as temperatures rise. Finally, our results highlight the essential role of the cost-effective RAD-Seq genomic assessment combined with tagging data to understand potential new colonisationsThis work was supported by the Spanish government (AEI), Ramon y Cajal postdoctoral program (#RYC2021-03438), Universitat de Barcelona, 2020 PREDOC-UB, MCIN/AEI/10.13039/501100011033 and ERDF/EU, BlueDNA (PID2023-146307OB), MICIU/AEI/10.13039/501100011033, MarGeCh (PID2020-118550RB), MICIU/AEI/10.13039/501100011033 and the ‘European Union NextGenerationEU/PRTR’, GenoMarTur (CNS2022-135205), Generalitat de Catalunya, SGR2021-01271, and Regional Partnership for Coastal and Marine Conservation (PRCM), ‘Survie des Tortues Marines’, and the Fundação. Fundação para a Ciência e a Tecnologia (FCT), UIDB/00329/2025 and 2023.07021.CEECIND/CP2831/CT0012. 10.54499/2023.07021.CEECIND/CP2831/CT0012With the institutional support of the ‘Severo Ochoa Centre of Excellence’ accreditation (CEX2019-000928-S)Peer reviewe
Global and local nature of cortical slow waves [Dataset]
No full textThis repository includes the required code and data to recreate the computational simulations and reproduce the results presented in the paper "Global and local nature of cortical slow waves", Alegre-Cortés, J; Mattia, M; Sáez, M; Reig, R. iScience 2025
It includes:
- The required code to reproduce the simulations of the computational models and its perturbations. Brian 2 is required to run the simulations.
- The code with all the functions necessary for the analysis of in vivo data presented in Fig. 2.
- Raw .nex files
- .xlsx file with the injection times of the in vivo experiments.
- README fileThis work is supported by "Centro de Excelencia Severo Ochoa" Grant CEX2021-001165-S, funded by MCIN/AEI/ 10.13039/501100011033; PID2021-129070NB-I00 funded by MCIN and Parkinson NEURO-AGING+; Parkinson. NEURO-AGING+ Ref. RECEUNAG2021; MULTISYN, Ref. CIPROM/2022/08, Generalitat Valenciana. JAC is supported by Ministerio de Universidad, European Union and Universidad Miguel Hernández de Elche through a Margarita Salas fellowship. MM is supported by funding from thec (PNRR), M4C2, funded by the European Union–NextGenerationEU (Project IR0000011, CUP B51E22000150006, “EBRAINS-Italy”).With funding from the Spanish government through the "Severo Ochoa Centre of Excelence" accreditation (CEX2021-001165-S)Peer reviewe
Effect of Cryodiluent and Time of Glycerol Addition on Cryopreservation and In Vitro Fertilization of Domestic Cat Epididymal Spermatozoa
No full textSperm cryopreservation and assisted reproduction are powerful tools for the conservation of endangered species. The domestic cat has been a useful model for studying wild felid reproductive biology due to the limited availability of endangered individuals for experimental research. Here, we investigate the effect of cryodiluents (TEST vs. Biladyl) and the timing of glycerol addition (before vs. after refrigeration, in one vs. three steps, respectively) on post-thaw sperm quality (motility, acrosome integrity) and their subsequent in vitro fertilization (IVF) ability with homologous oocytes. The results showed no statistically significant differences in sperm traits when samples were cryopreserved in TEST or Biladyl, or when glycerol was added in one or three steps. Motile sperm and intact acrosomes were significantly correlated before and after cryopreservation, indicating consistent relationships in fresh and thawed samples. The use of Biladyl significantly reduced IVF rates after cryopreservation compared to fresh sperm. Cryopreservation in TEST led to IVF rates that were not significantly different from those of fresh sperm. Using swim-up after thawing, or adding 1 mM pentoxifylline, did not enhance IVF results. Overall, a TEST cryodiluent with 4% glycerol added in one step is a reliable option for preserving epididymal cat spermatozoa.N.G. and R.G. received postgraduate studentships from the I3P-CSIC program. N.G. was also supported by a predoctoral grant from the BBVA Foundation. This research was funded by the Agencia Estatal CSIC, the Spanish Ministry of Environment and the BBVA Foundation.Peer reviewe
Exploring a Novel Anti-Inflammatory Therapy for Diabetic Retinopathy Based on Glyco-Zeolitic-Imidazolate Frameworks
No full text[Background/Objectives] Diabetic retinopathy is an ocular disease caused by changes in the expression of inflammatory mediators and increased oxidative stress in the retina and is the leading cause of vision loss in diabetic patients. Currently, there is no treatment capable of reversing retinal damage, which represents a significant burden on the quality of life of patients. (1R)-1-Dodecylsulfonyl-5N,6O-oxomethylidenenojirimycin stands outs as a prototype of the sp2-iminoglycolipids family for its beneficial neuroprotective effect against this chronic eye disease. Critical issues related to the low solubility and bioavailability of this glycolipid in biological settings are overcome by its encapsulation in a Zeolitic-Imidazolate Framework (ZIF) structure, resulting in homogeneous and biocompatible GlycoZIF nanoparticles. Cell studies show an enhanced cellular uptake compared with the free glycolipid, and importantly, its bioactivity is preserved once released inside cells.[Methods] Extensive in vitro and ex vivo assays with diabetic retinopathy models unveil the mechanistic pathways of the designed GlycoZIF.[Results] A reduction in proinflammatory mediators, increased heme oxygenase-1 level, inhibition of NLRP3 inflammasome, and reduced reactive gliosis is shown.[Conclusions] These findings demonstrate for the first time the potential of Glyco-modified ZIFs for the treatment of diabetes-related ocular problems by controlling the immune-mediated inflammatory response.This research was funded by the Ministerio de Ciencia, Innovación y Universidades and the Agencia Estatal de Investigación MICIU/AEI/10.13039/501100011033 and “ERDF/EU” (Grant numbers PID2022-141034OB-C22 to C.C.-C. and PID2022-141034OB-C21 to E.M.S.-F.) and the Instituto Salud Carlos III (PI22/01718 to A.I.A.) FEDER co-founded. Financial support was also provided by the University of Seville (VIPPIT-2020-IV.2 to C.C.-C., and VIIPPIT-2022-V.1 Modality A2 to E.M.S.-F. and C.C.-C.). R.R.-M. is an FPI fellow (Grant number PREP2022-000217).Peer reviewe