68994 research outputs found
Sort by
Environmental and behavioral drivers of Automatic Identification System gaps of Turkish trawlers in the Black Sea
No full textThis study investigates the spatial, temporal, environmental, and behavioral drivers of Automatic Identification System (AIS) signal gaps in trawl fishing vessels operating in the Black Sea. AIS deliberate or accidental signal gaps, which may cause vessels to become temporarily invisible to AIS-based surveillance systems, hinder maritime monitoring, compliance enforcement, and fisheries management — even though such vessels may still be detectable via alternative systems such as VMS. The analysis focused on two primary trawl types; bottom and pelagic trawl. Using a comprehensive dataset of AIS signals, environmental variables and vessel activity, the study integrated spatial and temporal analyses with XGBoost machine learning technique to identify key predictors of AIS gaps. The results reveal distinct seasonal and spatial patterns in AIS gap behavior, with significant variation between trawl types. For bottom trawls, AIS gaps were concentrated near the northern entrance of the Istanbul Strait, while pelagic trawls exhibited broader distributions along the Black Sea coast, particularly near Zonguldak and Samsun. Machine learning model demonstrated strong predictive performance, with an accuracy of 80.26%, AUC of 0.8855, TSS of 0.6052, MAE of 1336.74 minutes, and RMSE of 3205.54 minutes for bottom trawls. For pelagic trawls, the model achieved 61.68% accuracy, an AUC of 0.6663, TSS of 0.2336, MAE of 2011.05 minutes, and RMSE of 4400.40 minutes, indicating moderate predictive capabilities. Key predictors included environmental factors such as chlorophyll concentration and sea surface temperature, alongside spatial metrics like depth and proximity to shore and port. Partial dependence plots highlighted the non-linear effects of these variables, with chlorophyll concentration showing a critical threshold around 3.5 mg/m3 and sea surface temperature influencing gaps most significantly at approximately 15°C. This study provides the first systematic analysis of AIS gaps in Black Sea fisheries, contributing valuable insights into their drivers and implications for fisheries management. By identifying high-risk zones and temporal patterns, the findings could support improved monitoring strategies, regulatory enforcement, and sustainable resource use in this ecologically significant region
Circolazione dei dati relativi alla persona e rapporti giuridici
No full textIl volume, muovendo dall’idoneità dei dati personali a costituire oggetto di rapporti giuridici anche a contenuto patrimoniale, si propone di esaminarne le relative vicende circolatorie in una prospettiva sistematico-assiologica e relazionale. Avvalendosi di questo approccio di metodo, lo studio analizza le problematiche inerenti alla qualificazione e alla disciplina dei contratti che prevedono la circolazione dei dati personali, soffermandosi anche sulle implicazioni che ne derivano per le tutele dell’interessato
Nicotinamide N-methyltransferase as a determinant for resistance to radiotherapy in head and neck cancer
No full textHow can euthanasia and assisted suicide regulation guarantee patient health and autonomy? Lesson from nine European countries
No full textBackground: This paper aims to reflect on whether substantive limits should be implemented and what procedural rules should be introduced by legislators wishing to legalize euthanasia or assisted suicide (EAS) to guarantee health and autonomy of both the mentally ill and other patients. Methodology: We analyzed and compared the rules of the nine European States (the Netherlands, Belgium, Luxembourg, Austria, Portugal, Spain, Italy, Switzerland and Germany) where EAS is lawful. Discussion: The increase of countries that in the last years have implemented or introduced regulations on EAS leads us to think that: (a) substantive requirements should not be reduced, for example, allowing healthy people to access EAS; (b) substantive requirements must be ascertained through procedures that offer all of the guarantees of protection of the rights to life and self-determination provided for by the different regulations of the aforementioned countries, including, for example, clinical-psychological counselling to ensure autonomy of choice as well as preventive and ex-post control commission on compliance with substantive and procedural requirements. No law or ruling provided for the introduction of policies aimed at eliminating, before executing EAS, the socio-economic causes that led to the request to die. Perspective: The framework regulating EAS should be integrated with policies and measures to guarantee favorable family and socio-economic conditions, offer full access to palliative care, and allow free and equal decision-making
Nanoscale Ferroelectrics in High-Frequency Devices: Ab Initio Modeling and Multiscale Approach
No full textIn this paper, we investigate novel multi-physics simulations in both time and frequency domains to enable predictive modeling of nanoscale ferroelectric devices for highfrequency applications. Our approach addresses polarization dynamics in sub-10 nm hafnium-based ferroelectric films in the GHz range. We examine the ferroelectric material response up to 40 GHz under 30 dBm input power and assess conductor losses, including skin depth limitations and charge redistribution near the ferroelectric interface. The Density Functional Theory (DFT) approach has been used to gain insights into the interface phenomena of MIM diodes, demonstrating how advanced computational tools can predict the performance of nanoscale devices and guide fabrication choices. In particular, two different MIM diodes based on the orthorhombic Pca21 phases of HfO2 were examined. Since it is well known that oHfO2 exhibits intrinsic ferroelectric behavior, the MIM diodes were built to have spontaneous polarization toward the drain or the source electrode
Nonconventional yeasts in craft beer brewing
No full textYeast plays an important role in craft beer production. Indeed, they are responsible for the fermentation process but, above all, they can metabolize and produce many organic compounds that have a decisive impact on the final flavor of beer. In craft beer production, yeast variability may have a more relevant role in the characterization and complexity of flavor. In this regard, nonconventional yeasts may be of great interest due to their wide biodiversity and flavor production. In recent years, the growth of the craft beer market and the growing interest and demands of consumers have directed efforts toward the production of differentiated and innovative beer styles, and for these reasons, nonconventional yeasts have acquired a relevant role in the development of new products. This chapter discusses the use and potential application in the craft beer production sector of different nonconventional yeast species belonging to the genera Torulaspora, Lachancea, Pichia, Hanseniaspora, Schizosaccharomyces, and others will be described. The use of nonconventional yeasts for producing different beers as brew-flavored, nonalcoholic, low-calorie, and functional beers is reported. The main conventional yeast species used in the production of various craft beers are described
MTCH2 modulates CPT1 activity to regulate lipid metabolism of adipocytes
No full textMetabolic disorders, including obesity and metabolic-associated steatohepatitis, arise from a chronic energy surplus. Thus, enhancing energy dissipation through increased respiration holds significant therapeutic potential for metabolic disorders. Through a comprehensive analysis of human and murine adipose tissues, along with a functional screen, we identify mitochondrial carrier homolog 2, a mitochondrial outer membrane protein, as a pivotal regulator of mitochondrial metabolism. Intriguingly, its expression in adipose tissue is a strong determinant of obesity in humans. Adipocyte-specific ablation of mitochondrial carrier homolog 2 improves mitochondrial function and whole-body energy expenditure, independent of uncoupling protein 1. Furthermore, mitochondrial carrier homolog 2 regulates mitochondrial influx of free fatty acids by modulating the sensitivity of carnitine palmitoyltransferase 1 to malonyl-CoA through direct physical interaction, leading to enhanced energy expenditure in adipocytes/adipose tissue. Here we show mitochondrial carrier homolog 2 functions as a negative regulator of energy metabolism in adipocytes and represents a potential target for treating obesity and related metabolic disorders
Prolonged prone positioning in ARDS: No mortality benefit, no increased risk-But what about the reduced ICU staff workload?
Get PDFOptical Poling of Ferroelectric Liquids
Get PDFFerroelectric nematic liquid crystals combine fluidity, spontaneous polarity, optical birefringence, and strong nonlinear response, unlocking a rich landscape of phenomena and control strategies yet to be fully explored. Here, all-optical manipulation of polar domains and topological textures in ferroelectric nematic cells assembled from lithium niobate plates is demonstrated. In these devices, the photovoltaic response of the solid substrate couples to the fluid's polar director, enabling light-driven reorganization of the ferroelectric alignment. Under focused illumination in parallel-rubbed cells, the emergence of submillimeter-scale spiral-shaped radial domains is observed, in excellent agreement with the underlying material properties. Furthermore, it is shown that both domain structures and wall configurations can be reversibly reconfigured by varying light exposure, thereby tuning the degree of domain fragmentation and wall unpinning. These results establish light-induced polarization patterning as a versatile tool for dynamic control of nematic ferroelectric order, with promising applications in the design of reconfigurable linear and nonlinear photonic devices
NASpI e assegno di invalidità una proposta di rilettura del divieto di cumulo
No full textCon l’introduzione dell’art. 11 lettera e) D.Lgs. 4 marzo 2015, n. 22, che ha introdotto la decadenza del lavoratore dalla fruizione della NASpI nel caso dell’acquisizione del diritto all’assegno ordinario di invalidità, salvo il diritto del lavoratore di optare per la NASpI, si è posta la questione relativa alle tempistiche ed alle modalità di esercizio di tale diritto di scelta. Il saggio esamina gli itinerari dottrinari e giurisprudenziali in materia di rapporto tra NASpI e assegno di invalidità, con lo scopo di proporre una rilettura del divieto di cumulo