MTA-SZTE Research Group on Artificial Intelligence
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Developing a technology-based instrument for assessing inductive reasoning in kindergarten: applicability, validity and reliability
Heat Generation During Guided Bone Drilling: Bone Trephine Versus Pilot Drill
In the last decade, the use of surgical guides in dentistry has expanded to include endodontic surgery, yet most studies have focused on accuracy rather than potential heat generation. This in vitro study evaluated heat generation during bone drilling with custom-made bone trephines, both with and without static surgical guides, and compared the results to those of 2 mm pilot drills. Drilling was performed on porcine rib bone specimens under controlled conditions, with heat generation measured using an infrared thermometer. None of the groups exceeded the critical temperature of 47 °C; although, the guided trephine group recorded the highest peak temperature (7.9 °C above baseline). Significant differences in heat increments were observed among the groups. Post hoc analyses revealed that the guided pilot drill produced significantly lower heat increments compared to the trephine groups, particularly during the penetration of the second cortical layer and at peak temperatures (p < 0.05). The use of a surgical guide did not limit the cooling and lubricating effects of irrigation in the trephine groups. Regression analyses confirmed a strong relationship between drilling time and temperature increase, with guided trephines showing a steeper temperature rise compared to pilot drills. These findings emphasize the importance of proper irrigation, sharp instruments, reduced drilling speeds, and careful technique to minimize heat generation during guided bone drilling procedures
A számolási képesség fejlődése, az óvodások számolási képességét mérő tesztek, illetve ezek nyelvi fejlettséghez kapcsolódó kérdései
Enhancing sweet potato production: a comprehensive analysis of the role of auxins and cytokinins in micropropagation
Recommendations from the European guidelines for the diagnosis and therapy of pancreatic exocrine insufficiency
Pancreatic exocrine insufficiency (PEI) is defined as a reduction in pancreatic exocrine secretion below a level that allows normal digestion of nutrients. Pancreatic disease and pancreatic surgery are the main causes of PEI, but other conditions can affect the digestive function of the pancreas.In collaboration with European Digestive Surgery (EDS), European Society for Pediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN), European Society for Clinical Nutrition and Metabolism (ESPEN), European Society of Digestive Oncology (ESDO), and European Society of Primary Care Gastroenterology (ESPCG) the working group developed European guidelines for the diagnosis and therapy of PEI. United European Gastroenterology (UEG) provided both endorsement and financial support for the development of the guidelines.Recommendations covered topics related to the clinical management of PEI: concept, pathogenesis, clinical relevance, general diagnostic approach, general therapeutic approach, PEI secondary to chronic pancreatitis, PEI after acute pancreatitis, PEI associated with pancreatic cancer, PEI secondary to cystic fibrosis, PEI after pancreatic surgery, PEI after esophageal, gastric, and bariatric surgery, PEI in patients with type 1 and type 2 diabetes, and PEI in other conditions.The European guidelines for the diagnosis and therapy of PEI provide evidence-based recommendations concerning key aspects of the etiology, diagnosis, therapy, and follow-up, based on current available evidence. These recommendations should serve as a reference standard for existing management of PEI and as a guide for future clinical research. This article summarizes the recommendations and statements
Prevalence and Clinical Characteristics of the LRRK2 p. L1795F Variant in Central Europeans with Early‐Onset and Familial Parkinson's Disease
Valorization of waste biomass towards biochar production – Characterization and perspectives for sustainable applications in Serbia
Effect of obesity on postoperative complications in ulcerative colitis: A systematic review and meta-analysis
BackgroundThe prevalence of ulcerative colitis (UC) is around 200/100 000 people. Colectomy is required in 7.5%-40% of patients and 58.8%-94% of these operations are elective. Approximately one in two adults with UC are overweight or obese.ObjectiveOur aim was to compare postoperative complications between obese (defined by a body mass index (BMI) over 30 kg/m2) and non-obese UC patients who underwent total proctocolectomy with ileal pouch-anal anastomosis (IPAA).MethodsOur preregistered protocol can be found on PROSPERO (CRD42022377761). We conducted our search in three databases on the 26th of November 2022. PRISMA 2020 guideline and the Cochrane Handbook were applied. We used the GRADEpro program and the QUIPS tool. We applied a random-effects model to pool effect sizes. We included cohort and case-control studies investigating UC patients undergoing colectomy with IPAA and reported information on postoperative complications in obese and non-obese patients. We used mean difference (MD) for continuous variables and calculated odds ratio (OR) with a 95% confidence interval (CI) for dichotomous variables.ResultsOf the 6870 hits of our systematic search, we included three retrospective cohort studies for analyses involving 4929 patients in our research. Neither the incidence of complications at 30 days after surgery [OR = 1.08; CI: 0.65-1.79] nor the incidence of septic complications [OR = 1.11; CI: 0.85-1.46] had any clinical relevance, except for the length of hospital stay [MD = 0.36; CI:0.04-0.69]. When we assessed the risk of bias, we found that most of the aspects examined had a moderate overall risk. Our results have very low certainty of evidence.Conclusions and RelevanceOur findings suggest that obesity defined as BMI over 30 kg/m2 may not associated with an increased risk of higher rates of overall postoperative complications compared to non-obese patients. Obesity with a cut-off value of 30 kg/m2 does not appear to be a primary reason for prehabilitation. Our findings from 4929 UC patients suggest that obese patients probably do not differ to a clinically relevant extent from the non-obese population in the development of postoperative complications following IPAA surgery. Obesity with a cut-off value of 30 kg/m2 does not appear to be a primary reason for prehabilitation.imag