MTA-SZTE Research Group on Artificial Intelligence
SZTE Publicatio Repozitórium - SZTE - Repository of PublicationsNot a member yet
32192 research outputs found
Sort by
Development and validation of a psychometric scale for assessing pharmacy students' perceptions and attitudes toward antimicrobial resistance and antimicrobial stewardship in Indonesia: the PATARAS study
Get PDFAppropriate perceptions and attitudes of pharmacists toward antimicrobial resistance (AMR) are essential. However, AMR attitudes and perceptions have not been assessed in Indonesia. This study aimed to develop and validate a questionnaire to evaluate pharmacy students' Perceptions and Attitudes toward Antibiotic Resistance and Antimicrobial Stewardship (PATARAS) and investigate the relationship between students' perceptions and attitudes toward antibiotic resistance and stewardship. Using purposive sampling, 500 undergraduate pharmacy students were included in the study. The 20-item PATARAS questionnaire with 5-point Likert scales was developed. The PATARAS includes perception (rational drug use (RDU) and antimicrobial stewardship (AMS)) and attitude (professional role (PRO) and inappropriate practice (IPP)) domains. The validity (convergent and discriminant) of the PATARAS was investigated using confirmatory factor analysis (CFA). The CFA model fit was assessed using various goodness-of-fit indices. Reliability was assessed using Cronbach's alpha (α) and McDonald's Omega (ω) values. The relationship between subdomains was evaluated using structural equation modeling (SEM). The PATARAS questionnaire achieved acceptable convergent and discriminant validity. The CFA model achieved a good fit. The reliability was good with α and ω values of 0.817 and 0.845, respectively. The SEM showed that RDU and AMS were positively correlated with PRO (β = 0.121 and 0.539, respectively, p < 0.05); RDU and IPP were also positively correlated (β = 0.313, p < 0.05), while AMS and IPP were negatively correlated (β = - 0.275, p < 0.05). The PATARAS is a valid and reliable instrument for assessing undergraduate pharmacy students' perceptions and attitudes toward AMR and AMS
Led-based thermal lens spectrometry with a double-pass probe beam optimized configuration: A complete feasibility study
Get PDFElectrochemical Modulation of Hole Extraction in NiO/Perovskite Bilayers
Get PDFCharge extraction (or injection) at the transport layer/lead halide perovskite interface is a decisive process in determining the efficiency of optoelectronic devices. To elucidate the influence of band offsets on the hole transfer process, a series of perovskite thin films with systematically tuned valence band positions (FA 0.83 Cs 0.17 Pb(I x Br 1‐x ) 3 ) are fabricated and deposited on mesoporous NiO hole transport layers. In this work, transient absorption spectroscopy is performed to study the kinetics of hole transfer through the NiO/perovskite interface. It is revealed that a larger valence band offset is beneficial for hole extraction. To understand how hole depletion/accumulation influences the hole extraction process, in situ transient spectroelectrochemical measurements are also employed. These results highlight that, at negative applied electrochemical biases, an acceleration of the hole transfer process is found for different perovskite compositions. A more pronounced increase in the hole extraction rate can be tied to a larger valence band offset at the NiO/perovskite interface. These results provide a better understanding of the charge extraction process at NiO/perovskite interfaces, enabling more rational design of these systems
Comparing the Efficiency of Different Methods for Reliable Results in Ancient DNA NGS Workflow
Get PDFBackground/Objectives: Ancient DNA (aDNA) research workflows heavily depend on efficient aDNA extraction and NGS library preparation. In this study, we compared some of the commonly used laboratory protocols and compared the source of the bone material for sufficient and reliable results. Methods: We executed a three-phase study. First, we analyzed about 2000 previously processed archaic bone samples and conducted a comparative analysis. The second phase involved a controlled experiment of five ancient individuals, with internal control, to further investigate the efficiency of some of the methods. In the third phase, we made a comparison between the efficiency of two enzymes used for library preparation. Results: Samples made from Pars petrosa resulted in the highest yield of endogenous DNA and longer fragment sizes compared to tooth or skeletal samples. DNA extraction made by MinElute columns preserved slightly longer fragments than the handmade silica suspension. NGS libraries indexed using AccuPrime Pfx produced slightly more consistent insert sizes compared to GoTaq G2. Samples prepared with GoTaq G2 contained slightly more unique molecules. The duplication rates showed no significant impact from enzyme choice. Conclusions: Pars petrosa remains the most reliable source of aDNA, with the extraction method using MinElute columns. While AccuPrime Pfx ensures precise NGS library preparation, a more economical choice of the GoTaq G2 enzyme is a viable alternative for degraded archaic samples
Beneficial Therapeutic Effect of Endothelin‐Receptor Antagonist in Generalized Morphea: A Report of Two Cases
Get PDF
