JURNAL KIMIA MULAWARMAN
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Synthesis and Characterization of Copper(II) Oxide (CuO-NP) Nanoparticles using Chemical Precipitation Method
Full text linkThis study aims to optimize the calcination temperature and see the effect of adding surfactant on the bandgap, particle size, crystallinity level of CuO nanoparticles (CuO-NP), and the activity of CuO nanoparticles as an antibacterial agent. CuO-NP was successfully synthesized using the chemical precipitation method with variations in calcination temperature of 400, 600, and 800 °C with NaOH as a precipitating agent. The synthesized nanoparticles were further characterized using a UV-Vis, XRD, and SEM-EDX spectrophotometer. The value of the CuO-NP bandgap increases with increasing temperature. The bandgap gets bigger when the absorbance value gets smaller. Increasing the calcination temperature causes the crystal size of CuO-NP to become larger. The best level of crystallinity of CuO-NP was obtained at 68,31% with a calcination temperature of 600 °C. Adding 1% PVP did not significantly prevent agglomeration between CuO-NP particles, thereby increasing the size of CuO-NP particles.
Keywords: bandgap, CuO-NP, PVP, temperatur
Potential of Cow Bone as a Basic Material for Hydroxyapatite-High Density Polyethylene Composites (HAp-HDPE)
No full textCow bone has the potential to be used as a basic ingredient in the synthesis of hydroyapatite because it contains calcium. The addition of High Density Polyethylene (HDPE) to hydroyapatite aims to produce biocomposites that have better properties compared to the previous properties. The purpose of this study is to determine the characteristics of biocomposites with the HDPE:HAp in the ratio of 1: 2, 2: 1 and 3: 2 (%w / w). The method used is the sol-gel method and characterized by FTIR to see the bonding of functional groups and electron microscope to see the morphology of biocomposites. The biocomposites that have the best mechanical properties in this study are biocomposites with a ratio (HDPE: HAp) of 3: 2 with compressive and tensile strength values of 0.66 and 0.1290 N / mm2, density and water absorption values of 0.505 g / cm3 and 6,828% respectively and heat resistance with a temperature of 110 ° C experiencing a mass decrease of 0,675 g
The Effect of Soaking Time of Melinjo (Gnetum Gnemon L.) Peel Powder on Peroxide Numbers in Bulk Cooking Oil: The Effect of Soaking Time of Melinjo (Gnetum Gnemon L.) Peel Powder on Peroxide Numbers in Bulk Cooking Oil
Full text linkBulk oil is cooking oil that has gone through refining, bleaching, and deodorizing stages. Bulk cooking oil has been distributed in unpackaged form, which means that bulk cooking oil is exposed to oxygen before use. Incorrect storage over a period of time can cause the rupture of triglyceride bonds in the oil which eventually forms glycerol and free fatty acids (Yola, 2018). Bulk cooking oil that reacts with oxygen will cause the peroxide number to increase. High peroxide numbers are very dangerous for health. The content of saponins, tannins and flavonoids found in melinjo peel can be an antioxidant that acts as an antidote to free radicals so that it can slow down oxidation in bulk cooking oil. The purpose of this study was to determine the effectiveness of melinjo peel powder as an antioxidant with variations in soaking time on peroxide numbers in bulk cooking oil. This type of research is experimental with the number of repetitions of samples 16 From the results of the examination, the average peroxide number in bulk cooking oil that has been soaked is 0 day 22.7949 mEq, 4 days 19.5965 mEq and 8 days 9.5984 mEq. Statistical analysis using Kruskal-Wallis test obtained Sig value. 0.003 <0.05 indicates the effect of soaking time of melinjo peel powder on peroxide number in bulk cooking oil
Uji Aktivitas Antihiperurisemia Ekstrak Etanol Daun Sirsak (Annona muricata L) dan Analisis Komposisi Senyawa Yang Terkandung
No full textPenelitian mengenai uji aktivitas antihiperurisemia ekstrak etanol daun sirsak (Annona muricata L.) dan analisis komposisi senyawa yang terkandung telah selesai dilakukan. Metode yang digunakan adalah metode in vitro menggunakan spektrofotometer UV-Vis dan GC-MS. Kontrol positif yang digunakan adalah allopurinol. Berdasarkan hasil uji fitokimia diketahui bahwa ekstrak kasar etanol mengandung metabolit sekunder alkaloid, tannin dan saponin. Aktivitas enzim xantin oksidase pada residu sebesar 0,0004 U/mL dan supernatan sebesar 0,00009 U/mL. Berdasarkan aktivitas xantin oksidase terhadap ekstrak kasar etanol daun sirsak (Annona muricata L.) pada konsentrasi 0,00007 diperoleh daya inhibisi 82,5%. Berdasarkan hasil uji dengan alat GC-MS dari ekstrak etanol pada hasil uji aktivitas antihiperurisemia paling baik diperoleh 22 komponen senyawa, diantaranya terdapat 2 senyawa yang dominan yaitu Acid mono (2-ethylhexyl) ester sebesar 16,70% dan vitamin E sebesar 13,50%. Ekstrak kasar etanol daun sirsak (Annona muricata L.) memiliki potensi sebagai antihiperurisemia
VERIFIKASI METODE PENENTUAN SULFUR DIOKSIDA (SO2) PADA SAMPEL UDARA AMBIEN DENGAN METODE PARAROSANILIN MENGGUNAKAN SPEKTROFOTOMETER UV-VISIBELE
Full text linkThe research about verification method on determination of sulfur dioxide (SO2) on ambient air samples with the pararosaniline method using UV-Vis Spectrophotometer has been done. To obtain a valid measuring result, some important parameters of measurement on sulfur dioxide (SO2) in ambient air samples based on SNI 7119-7:2017. The results showed that the linearity of the measurement was very good as indicated by the correlation coefficient value was 0.9998. The limit of detection and limit of quantization was 2.7766 g/Nm3 and 7.4111 g/Nm3 respectively. The value of precision was good shown by %RSD < 2/3 CV Horwitz, and the accuracy of this method was good shown by a recovery percentage of 101.12%. Based on the results of this research, the pararosanilin method can be used to analyze sulfur dioxide (SO2) in ambient air samples with good results.
 
ANALISIS KADAR NITROGEN (N) TOTAL DAN BESI (Fe) PADA PENAMBAHAN BIOAKTIVATOR EM4 TERHADAP KOMPOS (SAMPAH KACANG PANJANG-KULIT KACANG KEDELAI)
Full text linkPengomposan merupakan proses penguraian bahan organik sampah dibawah kondisi-kondisi terkontrol oleh adanya aktivitas mikroorganisme pengurai. Proses pengomposan dilakukan dengan penambahan Effective microorgarnism 4 (EM4). Tahapan penelitian meliputi uji pengaruh waktu pengomposan terhadap suhu dan pH; penentuan variasi optimum bioaktivator EM4 terhadap kadar N-Total dan Fe serta waktu optimum pengomposan berdasarkan kondisi suhu, pH dan warna. Variasi optimum EM4 berdasarkan kadar N-Total pada variasi tanpa penambahan EM4 sebesar 0,4731% dan berdasarkan kadar Fe pada variasi EM4 20 mL sebesar 0,805%. Waktu optimum pengomposan berada pada hari ke-16 dengan pH 7,19-7,50; suhu sebesar 27-28,3°C dan memiliki warna hitam.
 
Formulation And Physical Stability Test Of Mother-In-Law’s Tongue Leaves Extract Lotion As An Antioxidant
Full text linkMother-in-law\u27s tongue leaves (Sansevieria trifasciata P.) is a plant of the genus Sansevieria with flavonoid compound namely trifasciatin, as an antioxidant. Antioxidants can be used in cosmetics to protect the skin from free radicals. The purpose of this research was to analyze antioxidant activity of mother-in-law\u27s tongue leaves extract and to obtain the best lotion formulation with various concentrations. Samples were extracted using 96% ethanol solvent with maceration method. Antioxidant activity was tested using DPPH method and intensity was measured at λ=517 nm by UV-Vis spectrophotometer. The IC50 value=49.72 ppm indicates a very strong antioxidant activity, compared to vitamin C=4.01 ppm (very strong). Extract was formulated in lotion with various concentrations of 0.5%, 1%, 3%, 6% and the comparison was vitamin C with same concentration as well as base without the addition of active substances. Based on observations for 4 weeks, 3% extract lotion is the best formulation. The organoleptic test results showed no change in shape, texture, color, odor, and pH so lotion was stable. In addition, the value of viscosity, spreadability, adhesion, irritation test according to established standards also has an antioxidant value 99.72% (strong category). So effective to ward off free radicals on the skin
SPECTROPHOTOMETRIC ANALYSIS OF CHLORAMPENICOL IN TIGER PRAWNS (PENAEUS MONODON) BASED ON THE DIAZOTATION REACTION: ANALISIS CHLORAMPENICOL PADA UDANG WINDU (PENAEUS MONODON) SECARA SPEKTROFOTOMETRI BERBASIS REAKSI DIAZOTASI
Full text linkSpectrophotometric analysis of chloramphenicol in tiger prawns (Penaeus Monodon) based on the diazotation reaction has been carried out. Sulfanilamide is used as a source of diazo salt to be coupled with chloramphenicol. In this study, several optimizations were carried out such as optimization of temperature, volume of HCl, volume of NaNO2, volume of sulfanilamide and contact time. Diazonium salt coupled with sulfanilamide produces a clear yellow compound with a maximum wavelength of 400.941 nm. The results of the analysis chloramphenicol on tiger shrimp, obtained the coefficient of variation were 4.026 %; 1.951 %; and 4.277 %.. Accuracy ranges from 99.7143% to 100.8730%. The Limit of Detection value is 6.24 mg/mL and the Limit of Quantization value was 20.803 mg/mL. The sensitivity value is 0.0021 mL /mg
AKTIVITAS ANTIKANKER SENYAWA PTEROKARPAN DARI KULIT BATANG AKA KALESI (Spatholobus ferrugineus)
Full text linkTujuan dari penelitian ini adalah untuk mengisolasi dan menguji aktivitas antikanker senyawa pterokarpan dari kulit batang Spatholobus ferrugineus (Zoll. & Moritzi) Benth terhadap MCF-7 yaitu sel kanker payudara. Terdapat dua senyawa turunan pterokarpan yang berhasil diisolasi yaitu senyawa variabilin (1) and medikarpin (2). Kedua senyawa tersebut dikarakterisasi dengan instrument 1D dan 2D NMR yang menyatakan bahwa kedua senyawa yang berhasil diisolasi adalah senyawa 1 dan 2. Senyawa 1 dan 2 menunjukkan aktivitas antikanker dengan nilai IC50 2,73 dan 14,36 μg/mL.
Kata kunci : pterokarpan, antikanker, Spatholobus ferrugineus, MCF-7.ABSTRACT
Two pterocarpan derivatives, variabilin (1), and medicarpin (2) were isolated from the stem bark of Spatholobus ferrugineus (Zoll. & Moritzi) Benth. The structures of 1-2 was determined based on UV, IR, 1D, and 2D NMR spectroscopic analysis. Anticancer activity of compounds 1-2 against breast cancer cells MCF-7 showed IC50 values of 2.73 and 14.36 µg /mL, respectively.
Keywords : Spatholobus ferrugineus, pterocarpan, anticancer, MCF-7 cells
Determination of Total Antioxidant and Phenolic Content from Malvaceae Family Leaves Infusion by Spectrophotometry
No full textThe use of plants as a source of medicine has been increasing lately. The plants used generally have bioactivities such as anti-bacterial, antioxidant, and others. Plants that contain antioxidants are widely used because of their ability to capture free radicals so that they can protect the body from various diseases. One of the plants that is often used is plants from the Malvaceae family. In this study, the antioxidant and total phenolic contents of five types of plants were determined. These plants were extracted by infundation method and analyzed using MPM (Modified Phenanthroline Method) and Folin-Ciocalteu methods. The highest antioxidant and total phenolic contents were found in kapok randu and waru leaves