Majalah Kedokteran Gigi Indonesia
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    Comparison of matrix metalloproteinase-13 and tissue inhibitor of metalloproteinase-1 levels and alveolar bone density in chronic periodontitis before and after scaling and root planning

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    Periodontitis is typically associated with disorders characterized by compromised tooth-supporting tissue. Damage to periodontal tissue is caused by an imbalance between matrix metalloproteinases and their inhibitors. Decreased tissue inhibitor and elevated matrix metalloproteinase levels result in collagen connective tissue and bone degradation. Several studies have shown that high levels of matrix metalloproteinase-13 (MMP-13) and low levels of tissue inhibitor of metalloproteinase-1 (TIMP-1) are also found in gingival crevicular fluid and saliva of patients with periodontitis. The purpose of this study was to determine the comparison of MMP-13 levels, TIMP-1 levels of saliva and bone density in patients with chronic periodontitis before and after scaling and root planning (SRP). The study samples were selected from patients who came for treatment at the Periodontics Installation of Universitas Sumatera Utara. A total of 16 patients were selected (n = 16) with a diagnosis of chronic periodontitis. The result showed that salivary MMP-13 levels in chronic periodontitis patients before SRP were higher than salivary MMP-13 levels after SRP and the difference was statistically significant (p 0.05). There was a negative correlation between clinical parameters and salivary TIMP-1 levels in patients with chronic periodontitis before and after SRP, but it was not statistically significant (p > 0.05)

    Osteoporosis detection using radiomorphometric examination and fractal dimensions through cone-beam computed tomography

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    Cone-beam computed tomography (CBCT) is becoming more widely used in the field of dentomaxillofacial radiography, but its utility for bone quality assessment is still limited. This study was conducted to describe the use of radiomorphometric examination and fractal dimensions (FDs) for osteoporosis risk detection through CBCT in elderly patients. Medical databases (PubMed, Scopus, Elsevier, and Directory of Open Access Journals (DOAJ)) were searched using the keywords osteoporosis, radiomorphometric, fractal dimension, and fractal analysis. The search limits applied were available full-text articles, publication years 2012-2021, and articles published available in English. Then, the articles included were systematically reviewed following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses. A total of four studies were included in this review. Seven radiomorphometric indices were used, and most indices were adopted from panoramic radiographs, such as the computed tomographycortical index, computed tomography mental index, computed tomography index, and four other indices along the mandible, which are the S (symphysis), A (anterior), M (molar), and P (posterior) indices. All of the radiomorphometric studies show similar results. These indices can identify osteoporosis-related changes and are useful as osteoporosis screening tools on CBCT. However, all FD studies show different methods and discover heterogeneous results. Radiomorphometric measurement methods in CBCT can be used to detect patients at risk for osteoporosis. The FD analysis method still finds heterogeneous research results, so it is recommended to standardize the method in terms of the shape, size, and location of the region of interest

    Partial maxillectomy pada ameloblastoma maksila di bawah anestesi umum

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    Tanggung jawab profesi terkait dengan hukum dalam pembuatan rekam medis

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    Caries risk factors based on cariogram among male smokers aged 15-24 years in Temanggung, Central Java, Indonesia

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    Temanggung Regency in Central Java is an area with an extensive tobacco farming, allowing its residents to have ease of access to cigarettes. In addition, it has become a tradition for locals in this area to serve any visiting guest with cigarettes. Adolescents start smoking to cope with the psychosocial crisis during their development, particularly when they try to find their identity. Smoking is, in fact, a risk factor for dental caries, so the adolescents in Temanggung have a quite high prevalence of caries. Thus, this study aimed to determine the sequence of the risk factors affecting the caries risk based on cariogram among male smokers aged 15-24 years (adolescents). This was a quantitative observational study with a cross sectional design. There were 152 subjects (n= 152) selected using a proportionate clustered random sampling out of the total population (316 adolescents). The research was carried out with a clinical examination of the oral cavity, measuring salivary secretions, examining the amount of plaque, and examining DMF-T. Scoring was done using a caliogram application. The results of this study showed that 81.3% of the adolescents had a moderate caries risk, while 18.1% of them had a high caries risk. The sequence of the risk factors affecting the caries risk based on cariogram was bacteria (22.90%), susceptibility (19.39%), dietary habits (12.09%), and other influencing conditions (7.55%)

    Evaluation on the use of plate positioning guide (PPG) on the placement accuracy of post-hemimandibulectomy plate reconstruction

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    Improper placement of the reconstruction plate can lead to postoperative complications. Placing reconstruction plates that have arch for operation is made easier with the plate positioning guide (PPG) as a transfer method of reconstruction plate. This study aimed to assess the impact of PPG on the placement accuracy of reconstruction plate as determined by the symmetrical breadth of the mandibular arch and the consistent placement of reconstruction plate following hemimandibulectomy. According to the inclusion criteria, this was a retrospective cross-sectional study with 12 participants (n = 12) after hemimandibulectomy. Subjects were divided into PPG (n = 6) and Non-PPG (n = 6) groups. Measurement of the difference in the width of the mandibular arch and the height of the placement of the reconstruction plate between the reconstructed and non-resected sides in three positions (anterior, posterior, and angulus) was conducted using submentovertex radiographs and orthopantomogram (OPG) through the RadiAnt DICOM Viewer software. The placement accuracy of the reconstruction plates was analyzed using a one-sample t-test with p-value 0.05. The results showed that the placement accuracy of the reconstruction plate in the PPG group were accurate (p = 0.590), and the Non-PPG group was inaccurate (p = 0.000); with the independent sample test. There was a significant difference between the two groups (p = 0.000). Plate positioning guide provides better symmetry of the mandibular arch width post-hemimandibulectomy

    Effect of the application of curcumin (Curcuma Longa) oral gel on periodontal inflammation in patients with type 2 diabetes melitus

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    Patients with Type 2 Diabetes mellitus (T2DM) were more prone to suffer from periodontitis due to unique alteration in host immune response. Application of curcumin oral gel as adjunctive therapy was expected to improve periodontal condition due to its anti-inflammatory properties. The objective of this study was to evaluate the effect of curcumin oral gel on periodontal inflammation in patients with T2DM. Sixteen periodontal pockets (n=16) from patients with T2DM were administered with curcumin oral gel using blunt cannula after periodontal curettage. Gingival Index (GI) and Periodontal Pocket Probing Depth (PPD) were evaluated a month after application. GI was assessed using visible sign of inflammation parameters including swelling, redness and bleeding upon probing. PPD was assessed using UNC-15 periodontal probe. The results were analyzed by Wilcoxon test (two related samples). The results showed that GI before treatment decreased by 51.61% a month post application. There was statistically significant difference (Sig 0.003) between GI mean before and after curcumin application. PPD decreased by 42.81% and showed statistically significant difference (Sig 0.000) by Wilcoxon Test. It is concluded that application of curcumin oral gel post curettage could decrease periodontal inflammation in patients with T2DM

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