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Video Abstract - Untersuchung der Produktionsweise und der institutionellen Bedingungen bei der Erstellung von Video Abstracts
Get PDFIm Bereich der wissenschaftlichen Recherche gibt das Abstract einen ersten Überblick über den Inhalt und die Ergebnisse eines Forschungsartikels. Das Format des Abstracts wird seit einigen Jahren auch in audiovisueller Form umgesetzt. Der Autor eines Papers kann zusätzlich zu seinem Artikel ein sogenanntes Video Abstract einreichen. Für die Erstellung eines Video Abstracts geben die Verlage bestimmte Richtlinien vor, die der Autor bei der Produktion einhalten soll. Diese Arbeit hat sich zum Ziel gesetzt, einen Standardisierungsansatz für institutionelle Bedingungen, auch Video Abstract Author Guidelines genannt, zu erarbeiten. Zu diesem Zweck wurden mit zwei Untersuchungen sowohl die Produktionsweise von Video Abstracts als auch die vom Verlag aufgestellten Guidelines analysiert. Mit den Ergebnissen der Untersuchungen wurde eine Handlungsempfehlung für die Verlage entwickelt. Außerdem ging aus den Ergebnissen hervor, dass einige Richtlinien Defizite aufweisen, welche die Verlage beheben sollten.In the field of scientific research, the abstract provides an initial overview of the content and results of a research article. The abstract format has also been implemented in audiovisual form for some years. The author of a paper can submit a so-called video abstract in addition to his article. For the production of a video abstract, the publishers specify certain guidelines that the author should adhere to during the production. This bachelor thesis aims to develop a standardization approach for institutional conditions, also called Video Abstract Author Guidelines. For this purpose, two studies were conducted to analyse both the production methods of video abstracts and the guidelines established by the publishers. The results of the studies were used to develop a recommendation for pub lishers. The results also showed that some guidelines have deficits that publishers should remedy
Analyse und Klassifizierung von Digitalisierungsinitiativen in der Landwirtschaft
Get PDFZiel der nachfolgenden Arbeit ist die Erhebung des aktuellen Stands der Digitalisierung in der Landwirtschaft. Es gilt herauszufinden, wie weit landwirtschaftliche Betriebe in Deutschland heute bereits digitalisiert sind. Parallel dazu soll erörtert werden, welche Gründe eine weitergehende Digitalisierung gegenwärtig verhindern. Dabei ist zu berücksichtigen, welche Bedeutung Digitalisierung in der Landwirtschaft hat. Zur Beantwortung der Forschungsfrage werden sowohl qualitative (Systematische Literaturanalyse) als auch quantitative Forschungsmethoden (Online-Umfrage mit anschließender statistischer Auswertung) angewendet. Wesentliche Erkenntnisse dieser Arbeit sind, dass die Messung von Digitalisierungsgraden landwirtschaftlicher Betriebe mittels eines Reifegradmodells signifikante Unterschiede in der deutschen Landwirtschaft widerspiegeln und dass der Kostenfaktor einen erheblichen Druck auf den digitalen Wandel im Agrarsektor ausübt. Generationenwechsel, sowie herstellerübergreifende Lösungen stellen neben der Forderung von mehr Unterstützung seitens der Politik und öffentlicher Institutionen Diskussionspunkte dieser Abschlussarbeit dar.The aim of the following work is to survey the current state of digitisation in agriculture. The task is to find out what extent farms in Germany are already digitised today. In parallel, the reasons that currently prevent further digitisation are to be discussed. In doing so, the importance of digitisation in agriculture must be taken into account. To answer the research question, both qualitative (systematic literature analysis) and quantitative research methods (online survey with subsequent statistical analysis) are used. Key findings of this work are that the measurement of digitisation levels of agricultural enterprises by means of a maturity model reflects significant differences in German agriculture and that the cost factor exerts considerable pressure on the digital transformation in the agricultural sector. Generation changes, as well as cross-manufacturer solutions, represent discussion points of this thesis, in addition to the demand for more support from politics and public institutions
Potential of ESBL-producing Escherichia coli selection in bovine feces after intramammary administration of first generation cephalosporins using in vitro experiments
Get PDFSelection and spread of Extended Spectrum Beta-Lactamase (ESBL) -producing Enterobacteriaceae within animal production systems and potential spillover to humans is a major concern. Intramammary treatment of dairy cows with first-generation cephalosporins is a common practice and potentially selects for ESBL-producing Enterobacteriaceae, although it is unknown whether this really occurs in the bovine fecal environment. We aimed to study the potential effects of intramammary application of cephapirin (CP) and cefalonium (CL) to select for ESBL-producing Escherichia coli in the intestinal content of treated dairy cows and in manure slurry, using in vitro competition experiments with ESBL and non-ESBL E. coli isolates. No selection of ESBL-producing E. coli was observed at or below concentrations of 0.8 µg/ml and 4.0 µg/ml in bovine feces for CP and CL, respectively, and at or below 8.0 µg/ml and 4.0 µg/ml, respectively, in manure slurry. We calculated that the maximum concentration of CP and CL after intramammary treatment with commercial products will not exceed 0.29 µg/ml in feces and 0.03 µg/ml in manure slurry. Therefore, the results of this study did not find evidence supporting the selection of ESBL-producing E. coli in bovine feces or in manure slurry after intramammary use of commercial CP or CL-containing products
Treatment Patterns and Healthcare Resource Utilization Among Patients with Atopic Dermatitis: A Retrospective Cohort Study Using German Health Claims Data
Get PDFIntroduction
Atopic dermatitis (AD) is a common inflammatory skin disease. Many patients are initiating a systemic therapy, if the disease is not adequately controlled with topical treatment only. Currently, there is little real-world evidence on the AD-related medical care situation in Germany. This study analyzed patient characteristics, treatment patterns, healthcare resource utilization and costs associated with systemically treated AD for the German healthcare system.
Methods
In this descriptive, retrospective cohort study, aggregated anonymized German health claims data from the InGef research database were used. Within a representative sample of four million insured individuals, patients with AD and systemic drug therapy initiation (SDTI) in the index year 2017 were identified and included into the study cohort. Systemic drug therapy included dupilumab, systemic corticosteroids (SCS) and systemic immunosuppressants (SIS). Patients were observed for one year starting from the date of SDTI in 2017.
Results
9975 patients were included (57.8% female, mean age 39.6 years [SD 25.5]). In the one-year observation period, the most common systemic drug therapy was SCS (> 99.0%). Administrations of dupilumab (0.3%) or dispensations of SIS were rare (cyclosporine: 0.5%, azathioprine: 0.6%, methotrexate: 0.1%). Median treatment duration of SCS, cyclosporine and azathioprine was 27 days, 102 days, and 109 days, respectively. 2.8% of the patients received phototherapy; 41.6% used topical corticosteroids and/or topical calcineurin inhibitor. Average annual costs for medications amounted to € 1237 per patient. Outpatient services were used by 99.6% with associated mean annual costs of € 943; 25.4% had at least one hospitalization (mean annual costs: € 5836). 5.3% of adult patients received sickness benefits with associated mean annual costs of € 5026.
Conclusions
Despite unfavorable risk–benefit profile, this study demonstrated a common treatment with SCS, whereas other systemic drug therapy options were rarely used. Furthermore, the results suggest a substantial economic burden for patients with AD and SDTI
Wann fahren wir autonom? Eine Untersuchung aus technischer und rechtlicher Sicht.
Get PDFAutonomes Fahren rückt immer mehr in den Fokus der Gesellschaft. Im Gesetz zum autonomen Fahren sieht die deutsche Bundesregierung einen Meilenstein, der die Realisierung des autonomen Fahrens ermöglicht. Dennoch sind keine serienreifen, autonomen Fahrfunktionen auf deutschen Straßen zugelassen. Wie weit sind wir noch vom Traum vom autonomen Fahren entfernt? In diesem Beitrag wird untersucht, welche offenen Fragen es aus juristischer und technischer Sicht gibt und in welchen Punkten beide Disziplinen aufeinander warten. Der aktuelle Stand wird in den Bereichen Typgenehmigung/Zulassung, Fahrerlaubnis (Führerschein) und Haftung systematisch untersucht. Mit Hilfe eines Gedankenexperiments, bei dem der menschliche Fahrer durch einen Roboterfahrer ersetzt wird, wird eine einheitliche Basis geschaffen, um automatisierte Fahrfunktionen und Fahrerassistenzsysteme zu vergleichen. Dieser Beitrag deckt offene Fragen auf, die für die Realisierung des vollständig autonomen Fahrens noch beantwortet werden müssen. Eine praktische Umsetzung erfordert eine enge interdisziplinäre Zusammenarbeit, insbesondere von Expert*innen aus den Bereichen Regulierung, Technik und Sozialwissenschaften
Ralph-Christian Amthor, Carola Kuhlmann und Birgit Bender-Junker (Hrsg.) (2022) Kontinuitäten und Diskontinuitäten Sozialer Arbeit nach dem Ende des Nationalsozialismus. Band 1: Berufsbiografische Verläufe zwischen ideologischen Kontinuitäten, Migration und Reeducation.
Get PDFDer Artikel bespricht den ersten Teil des Tagungsbands "Kontinuitäten und Diskontinuitäten Sozialer Arbeit nach dem Ende des Nationalsozialismus". Der Band wurde von Ralph-Christian Amthor, Carola Kuhlmann und Birgit Bender-Junker herausgegeben und enthält 19 Beiträge. Er beschäftigt sich mit der bisher wenig erforschten Nachkriegs- und Übergangszeit nach dem zweiten Weltkrieg in Bezug auf Kontinuitäten und Diskontinuitäten Sozialer Arbeit
Impact of exercise training on symptoms of depression, physical activity level and social participation in people living with HIV/AIDS: a systematic review and meta-analysis
Get PDFBackground
Symptoms of depression are prevalent in people living with human immune deficiency virus/acquired immune deficiency syndrome (PLWHA), and worsened by lack of physical activity/exercises, leading to restriction in social participation/functioning. This raises the question: what is the extent to which physical exercise training affected, symptoms of depression, physical activity level (PAL) and social participation in PLWHA compared to other forms of intervention, usual care, or no treatment controls?
Method
Eight databases were searched up to July 2020, according to the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) protocol. Only randomised controlled trials involving adults who were either on HAART/HAART-naïve and reported in the English language, were included. Two independent reviewers determined the eligibility of the studies, extracted data, assessed their quality, and risk of bias using the Physiotherapy Evidence Database (PEDro) tool. Standardised mean difference (SMD) was used as summary statistics for the mean primary outcome (symptoms of depression) and secondary outcomes (PAL and social participation) since different measuring tools/units were used across the included studies. Summary estimates of effects were determined using a random-effects model (I2).
Results
Thirteen studies met the inclusion criteria with 779 participants (n = 596 participants at study completion) randomised into the study groups, comprising 378 males, 310 females and 91 participants with undisclosed gender, and with an age range of 18–86 years. Across the studies, aerobic or aerobic plus resistance exercises were performed 2–3 times/week, at 40–60 min/session, and for between 6-24 weeks, and the risk of bias vary from high to low. Comparing the intervention to control groups showed significant difference in the symptoms of depression (SMD = − 0.74, 95% confidence interval (CI) − 1.01, − 0.48, p ≤ 0.0002; I2 = 47%; 5 studies; 205 participants) unlike PAL (SMD = 0.98, 95% CI − 0.25, 2.17, p = 0.11; I2 = 82%; 2 studies; 62 participants) and social participation (SMD = 0.04, 95% CI − 0.65, 0.73, p = 0.91; I2 = 90%; 6 studies; 373 participants).
Conclusion
Physical exercise training could have an antidepressant-like effect in PLWHA but did not affect PAL and social participation. However, the high heterogeneity in the included studies, implies that adequately powered randomised controlled trials with clinical/methodological similarity are required in future studies
Herausforderungen und Lösungsansätze im Datenmanagement am Beispiel eines Energieversorgers
Get PDFDaten sind für jedes Unternehmen die treibende Kraft und die konsistenteste Quelle für qualifizierte Entscheidungsprozesse. Für die optimale Nutzung der vorliegenden Daten über alle Geschäftsbereiche hinweg wird das Datenmanagement benötigt, jedoch bringt dessen Einführung große Herausforderungen mit sich. Wird es nicht eingeführt bzw. umgesetzt hat dies Folgen für das Unternehmen wie z. B. Wettbewerbsnachteile und hohe Kosten. Ziel dieser Bachelorarbeit ist es von Datenmanagement, den Nutzen aufzuzeigen, die Herausforderungen zu identifizieren und Lösungsansätze zu untersuchen bzw. eigene zu entwickeln. Das Ergebnis ist eine Untersuchung und ein Vergleich des Nutzens, der Herausforderungen sowie der Lösungsansätze im Datenmanagement, zwischen Literatur und einem Anwendungsfall.Data is the driving force for every company and the most consistent source for qualified decision-making processes. Data management is needed to make the best use of the available data across all business units, but its implementation brings major challenges. If it is not introduced or implemented, this has consequences for the company, such as competitive disadvantages and high costs. The aim of this thesis is to show the benefits of data management, to identify the challenges and to investigate and develop solutions. The result is an investigation and comparison of the benefits, challenges and solutions in data management between literature and a use case
Future Profile of LIS Study Programs at Hanover University of Applied Sciences and Arts
Get PDFDer Beitrag beschreibt die aktuellen Überlegungen zur Weiterentwicklung der informationswissenschaftlichen Studiengänge der Hochschule Hannover vor dem Hintergrund des laufenden Prozesses der Reakkreditierung. Zentrale Aspekte bilden hierbei die inhaltliche und strukturelle Weiterentwicklung des Curriculums vor dem Hintergrund der sich verändernden Bedürfnisse der Bibliotheken. Ebenfalls berücksichtigt werden verschiedene Formen der Kooperation mit der Bibliothekspraxis, hochschuldidaktische Überlegungen sowie die Einbindung der Studiengänge in die informationswissenschaftliche Forschungslandschaft.The article describes the current considerations for the further development of information science courses at Hannover University of Applied Sciences and Arts with respect to the ongoing process of reaccreditation. Central aspects are the further development of the curriculum in terms of content and structure against the background of the changing needs of libraries. It also considers various forms of cooperation with libraries, concerning university teaching considerations, and the integration of study programs into the information science research landscape
Patient Benefit of Clinical Research in Diversely Advanced African Developing Countries
Get PDFBackground: The globalization of clinical research should also benefit the population in developing markets. In this context, the approval of tested medicines and the associated expansion of medical care beyond clinical studies would be desirable as a possible long-term benefit.
Objectives: This study was designed to compare the development of the number of clinical trials with the number of marketing authorizations of medicines on the African continent. To contrast these 2 parameters, the data were analyzed using the model of an ecological study.
Methods: To reflect the broad spectrum of African developing countries with diverse levels of development, the data collection was based on 2 geographically selected sample countries each from Central, North, East, West, and Southern Africa. Based on the ClinicalTrials.gov registry, the first step was to collect trends data on the development of the clinical trials in the 10 selected countries of the country list of the African Region published by the World Health Organization for the period 2015 to 2018. Subsequently, data on the current number of marketing authorizations of medicines in the selected sample countries were identified using the online registries of the national authorities. The data were utilized in comparative analyses.
Results: Eight out of 10 model countries showed an increase in the number of clinical trials, with the exceptions of Cameroon and Libya, which showed an overall decline in research activity over the entire time. In direct comparison with drug registrations, the numbers indicate a similar development. The only exception here is Nigeria, a country with a solid performance in clinical research and yet a decrease in medicine registrations since 2015.
Conclusions: The expected increase in the development of clinical research as result of the globalization trend can basically be observed in most of the model countries. However, this increase does not guarantee an improvement in the number of medicine registrations. Although this is evident in some of the selected model countries, it cannot be projected to the entire African region. This may be linked to the diverse development of the individual countries due to the different political situations and the varying degrees of clinical research infrastructure