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A new formulation of Ni/Zn bi-metallic nanocomposite and evaluation of its applications for pollution removal, photocatalytic, electrochemical sensing, and anti-breast cancer
No full textNanocomposites have gained attention due to their variety of applications in different fields. In this research, we have reported a green synthesis of a bi-metallic nanocomposite of nickel and zinc using an aqueous extract of Citrus sinensis in the presence of chitosan (Ni/Zn@orange/chitosan). The nanocomposite was characterized using different techniques. We have examined various applications for Ni/Zn@orange/chitosan. The NPs were man-ufactured in spherical morphology with a particle range size of 17.34-90.51 nm. Ni/Zn@orange/chitosan showed an acceptable ability to remove dyes of Congo red and methyl orange from an aqueous solution after 80 min furthermore, it uptaking the drug mefenamic acid from a solution. Ni/Zn@orange/chitosan also exhibited great photocatalytic activity in synthesizing benzimidazole using benzyl alcohol and o-phenylenediamine. Ni/ Zn@orange/chitosan was found as a potent electrochemical sensor to determine glucose. In the molecular and cellular section of the current research, the cells with composite nanoparticles were studied by MTT way about the anti-breast adenocarcinoma potentials malignant cell lines. The IC50 of composite nanoparticles were 320, 460, 328, 500, 325, 379, 350, and 396 & mu;g/mL concering RBA, NMU, SK-BR-3, CAMA-1, MCF7, AU565, MDA-MB-468, and Hs 281.T breast adenocarcinoma cell lines, respectively. The results revealed the newly synthesized nanocomposite is a potent photocatalyst, dye pollution removal agent, and an acceptable new drug to treat breast cancer
Effect of Hypnosis in Adolescents: A Narrative Review
No full textBackground: More than half of reproductive-age women experience dysmenorrhea, which can reduce their quality of life. The treatment options for dysmenorrhea are medications and alternative therapies. The tendency to use alternative therapies, such as hypnotherapy has increased.Objectives: This study aimed to carry out a narrative review to evaluate the effect of hypnosis on dysmenorrhea in adolescents. Methods: EMBASE, Web of Science, Scopus, Google Scholar, PubMed, Cochrane library ProQuest and clinicaltrials.gov were searched up to 2021 using the following keywords "dysmenorrhea", "hypnosis". The quality of studies was assessed by Cochrane collaboration's tool and the risk of bias in the non-randomized studies of interventions (ROBINS-I) tool.Results: Nine studies with a sample size of 5203 participants were included. The hypnosis intervention similar to drug therapy was effective in reducing the intensity of dysmenorrhea and improving the women's quality of life. Dysmenorrhea pain scores in hypnosis and drug therapy groups were significantly lower than those at baseline, but pain scores in the drug therapy group were significantly lower than in the hypnosis group.Conclusions: Hypnosis can provide lasting pain relief compared to NSAIDs. Therefore, it is recommended that hypnosis as a complementary or alternative therapy reduce the intensity of dysmenorrhea in adolescents
No sign of Rotavirus co-infection in COVID-19 patients with gastrointestinal symptoms
No full textBackground and aims The main goal of the present study is to investigate the incidence of Rotavirus co-infection in COVID-19 patients. Methods and Results Fecal samples of COVID-19 patients with gastrointestinal symptoms which had positive PCR-were collected from Abadan's hospital, Iran during the period December 2020 to January 2021. Samples were analyzed by RT-PCR to determine the presence of Rotavirus. Finally, the total samples size of 37 were included in this study. The mean age of patients was 48.22 years. Abdominal pain alone was detected in 48.65 of the patients. At least one gastrointestinal symptom was detected in all of the patients. Diarrhea and fever were seen in 13.51 and 59.46 of patients, respectively. Nausea and vomiting were seen in 5.41 of the patients. RT-PCR showed no infection of Rotavirus among the patients. Conclusion Gastrointestinal symptoms related to COVID-19 are common. More studies is need among these patients groups for investigate co-infection with other fecal viral shedding carries, due to a worse prognosis and its association with disease severity
Oxidative balance score and dietary phytochemical index can reduce the risk of colorectal cancer in Iranian population
No full textBackgroundNo previous study has assessed the association between oxidative balance score (OBS) and dietary phytochemical index (DPI) with colorectal cancer (CRC) simultaneously. Therefore, this study investigated the association between OBS and DPI with the odds of CRC among the Iranian population.MethodsThis hospital-based age and sex-matched case-control study was conducted between September 2008 and January 2010 (142 controls and 71 cases were entered for analysis). New diagnosed CRC cases were selected from the Cancer Institute, Imam Khomeini Hospital of Tehran. Dietary intakes were determined by a semi-quantitative food frequency questionnaire (FFQ). Then, dietary indices were calculated by food items and nutrient intake. Logistic regression was utilized for assessing the tertiles of OBS and DPI.ResultsIn multivariate analysis, OBS was associated with a 77 reduction in CRC odds in the last tertile than the first tertile (odds ratio (OR) = 0.23, confidence interval (CI): 0.07-0.72, P-trend = 0.017). Also, we found a 64 reduction in CRC odds in the last tertile of DPI compared to the first tertile (OR = 0.36, CI: 0.15-0.86, P-trend = 0.015).ConclusionsA diet rich in phytochemicals and anti-oxidants, including fruits and vegetables (citrus fruits, colored berries, and dark-green leafy vegetables) and whole grains, may reduce the CRC odds
Fabricating modified carbon sesame straw for adsorption of acetaminophen and ibuprofen from aqueous media: isotherm and kinetic models
No full textAs acetaminophen (ACT) and ibuprofen (IBP) have serious environmental impacts, despite their widespread use in many countries, the present research examined the effectiveness of activated carbon made from straw and sesame stubble in removing ACT and IBP from water. To that end, the as-synthesized adsorbent was functionalized using zinc chloride. The maximum adsorption capacities were found to be 51.7 mg g(-1) for ACT and 63.7 mg g(-1) for IBP. The adsorption kinetics and isotherm results showed that the pseudo-second-order (PSO) kinetics and Langmuir isotherm fit the data obtained from this study better than the other experimental models do. Also, the adsorption reached equilibrium within 120 min, and the optimal adsorbent dose and temperature were obtained as 1.0 mg and 25 degrees C, respectively. The mechanisms involved in the adsorption process would include acid-base, hydrogen bonding, electrostatic forces, and pi-pi interaction. Reusability studies revealed that the adsorbent still preserved about 89 and 82 of the adsorption performance for ACT and IBP, respectively, after seven repeated adsorption cycles. As the findings indicated, CSS/Zn could be accepted as a hopeful adsorbent to be used in pharmaceutical treatment
Dietary quality index and the risk of breast cancer: a case-control study
No full textBACKGROUND: Diet quality is a significant determinant in the etiology of breast cancer (BrCa), but further studies are required to explore this relationship. Therefore, we tried to assess if diet quality, assessed using the Diet Quality Index-International (DQI-I), was related to BrCa among the Iranian population. METHODS: In the present case-control research, 134 women with a recent diagnosis of BrCa and 267 without BrCa were selected as case and control groups. Individual food intake data from a food frequency questionnaire was used to compute DQI-I. Also, the multivariable logistic regression models were utilized to evaluate the association between DQI-I and BrCa odds . RESULTS: We found a significant association between the last tertile of DQI-I and BrCa odds in the fully adjusted model (odds ratio (OR) = 0.30; 95 confidence interval (CI): 0.15-0.56). The subgroup analysis based on menopausal status also showed a significant decrease in BrCa odds in pre-and post-menopausal women (pre-menopausal: OR = 0.27; 95 CI: 0.10-0.70 - post-menopausal status: OR = 0.35; 95 CI: 0.13-0.92). CONCLUSIONS: Our findings indicated that a higher DQI-I score was related to a lower chance of BrCa. According to our research, a healthy diet pattern is crucial for BrCa prevention
Blood Levels of D-Dimer and its Relationship with the Occurrence of Headache in Patients with Type 2 Diabetes Infected with COVID-19
No full textBackground and purpose: The SARS-CoV-2 can increase blood levels of D-dimer by causing thrombosis and affecting the homeostasis system. This study aimed at investigating the blood levels of D-Dimer and its relationship with the incidence of headache in patients with type 2 diabetes infected with COVID-19 who were admitted to Ilam Shahid Mostafa Hospital, Iran. Materials and methods: We studied the patients hospitalized in Ilam Shahid Mostafa Hospital. with COVID-19 (n=988) in two groups of with and without diabetes. Blood levels of D-dimer, and glucose, and also the incidence of headache were evaluated in all patients. Results: Fasting blood sugar levels, blood levels of D-dimer, white blood cell count, and ESR significantly increased in diabetic patients with COVID-19 compared with the non-diabetic patients (P<0.001). The incidence of headache was found to be significantly lower in diabetic patients than non-diabetic patients (n= 91, P= 0.0009). Conclusion: According to present research, there is an inverse relationship between the blood levels of D-dimer and incidence of headache in diabetic people with COVID-19, as by increase in blood levels of D-dimer the incidence of headache decreased. © 2023, Mazandaran University of Medical Sciences. All rights reserved
The Relationship between Clinical Competence and Ethical Reasoning and Factors Affecting it in Nurses Working in Therapeutic Educational Centers of Ilam
No full textClinical competence means a person's ability to use techniques on time, to communicate effectively with others, and to benefit from the knowledge and clinical reasoning ability when responding to different clinical situations in such a way that a person can use these skills at all times. The aim of the study is the relationship between clinical competence and ethical reasoning and the factors affecting it in nurses working in therapeutic educational centers of Ilam. Methods: In this descriptive-analytical study, 110 nurses working in three therapeutic educational centers in Ilam city were randomly selected. Demographic information forms, standard nursing clinical competence questionnaire (NCCQ), and nursing dilemma test (NDT) were used to collect data. The results also showed a positive and significant relationship between age, level of education, years of work experience, employment status, and occupational role with clinical competence and ethical reasoning (P<0.05). On the other hand, there was an inverse and significant relationship between the workplace and clinical competence and ethical reasoning (P<0.05). Data analysis was carried out using Descriptive statistics (frequency, percentage, mean and standard deviation) and analytical tests (Pearson correlation tests and analysis of variance) in SPSS. P-value< 0.05 was considered as the significance level. Using the results of the present study, nursing education planners and managers can periodically organize workshops on nursing ethics and nursing problems in hospitals and universities. Moreover, clinical competence and ethical reasoning should be taken into account when training nursing personnel in university classrooms and in-service courses
A five-year systematic review and meta-analysis study on methicillin resistant Staphylococcus epidermidis strains in Iran
No full textBackground and Objectives: One of the most prevalent drug-resistant bacteria is methicillin-resistant Staphylococcus epi-dermidis (MRSE) causing healthcare infections. Previously, a meta-analysis study on the frequency of MRSE was conducted from Mar 2006 to Jan 2016 in Iran. The present study aimed to evaluate the changes in this prevalence in the last 5 years in different cities in Iran.Materials and Methods: Published articles on the frequency of MRSE were collected from the Web of Science, PubMed, Scopus, Google Scholar, Cochrane Library, and Iranian databases from the beginning of 2016 to the end of 2020. Of the 503 records identified, 17 studies met the inclusion criteria, and their extracted data were analyzed using comprehensive meta-analysis version 2.0 (Biostat).Results: The analysis showed that the frequency of MRSE has decreased significantly in the last five years and reached 60.8 95% confidence interval (95% CI) 54.2-66.9 among culture-positive cases of S. epidermidis in Iran.Conclusion: The noticeable reduction in the prevalence of MRSE in Iran could be due to the improvement of infection con-trol programs and interruption of the pathogen transmission cycle. Another influential reason is the significant reduction in methicillin prescriptions by physicians for infections caused by staphylococci