Sains Medika: Jurnal Kedokteran dan Kesehatan
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The Difference in The Effect Between The Oxygenated and Mineral Water on The O2 Saturation And Urine pH
Full text linkBackground: During exercise, oxygen decreases due to acidosis leading the production acid urine by kidney. Oxygenated water having capability to absorb more oxygen compared to mineral water is used to meet the oxygen need during exercise. This study investigated the effect of oxygenated water and mineral water on the O2 saturation and urine pH.Design and method: In this crossover study, 46 subjects were randomly assigned to either oxygenated water or mineral water for 24 hours followed by a crossover to the other regimen for an additional 24 hours of treatment. After 100 m sprint running for 20 minutes, the oxygen saturation and urine pH of the subjects were assessed.Result:The mean oxygen saturation before and after the treatment of oxygenated water were 96.78±1.32 and 97.61±0.93 respectively. The mean oxygen saturation before and after the mineral water treatment was 97.35±0.85 and 97.01±1.04 respectively. The urine pH after the administration of oxygenated water and mineral water were 6.643±0.69 and 6.585±0,58 respectively. Wilcoxon test resulted in no significant difference in pH after the treatment of oxygenated water and mineral water (p=0.498). Urine pH after the treatment of oxygenated water was found to be higher compared to that of mineral water.Conclusion: the oxygenated water increases the O2 saturation and urine pH compared to mineral water (Sains Medika, 3(2):162-167)
Fostering Medical Students’ Leadership and Team Building Skills and Respect toward Other Health Profession through Inter-Professional Education Analysis of Its Possible Application in Indonesian Medical Schools
Full text linkInter-professional learning is becoming a very hot issue in medical education field in Indonesia nowadays. Many medical faculties carried out discussions about this topic to consider the possibility to apply the method of learning in their own faculties. This writing is a critical review of an article concerning multiprofessional learning in medical field and an analysis of its possible implications to improve the quality f medical education in Indonesia (Sains Medika, 3(1):89-101)
Hyperexpression of TNF-Stimulated 6 (TSG-6) of HumanTracheal Aspirate and Bronchial Alveolar Lavage from Heavy-Smoker and Lung TB
Full text linkBackground: TSG-6, an inflamation-associated protein, forms covalent complexes with heavy-chains from TNF. These protein potentiating the antiplasmin activity of this serine protease inhibitor. The aim of study was to determine and show that TSG-6 are present in Bronchoalveolar Lavage (BAL) from patients with lung TB and heavy smoker.Design and Methods: Experiments conducted in vitro with purified components revealed that TSG-6 had immunodetection in the Human Tracheal Aspirates (HTA) and BAL of heavy smoker and Lung Tuberculosis.Results: Immunoprecipitation revealed that TSG-6 accounts in airways hyperresponsiveness for significant proportion of BAL and HTA, but not in control (p < 0,01). TSG-6 relevant protease inhibitor in airway secretion. In primary cultures of differentiated human airway epithelial, which suggest that TSG-6 may be induced by TNF. Our results suggest that TSG-6 may play an important protective role in bronchial epithellium buy increasing the antiprotese screen on the airway lumen. The present study identifies a novel function of TSG-6 by a distinct mechanism system regulated, enhancement of anti TK activity, and provides a rational for this activity within the context of inflamed airways. These findings correlate with the observed increases in protein expressions in human HTA and BAL.Conclusions: TSG-6 are hyper-expressed in airway epithelial cells in cultures of smoker and lung TB. The interactions of TSG-6 with other molecules are also potentially important to the pathophysiologic aspects of inflammatory airways diseases that remain to be elucidated (Sains Medika, 3(1):31-40)
The Difference in Effectiveness of 70% and 0.5% Chlorine to ReduceThe Germ Number on Stethoscope’s Membrane Experimental research at stethoscope in Baitul Izah Ward of Sultan Agung Islamic Hospital Semarang
Full text linkBackground: Recently, nosocomial infection (hospital- acquired infections) is estimated to affects more than 1.4 million of in patients in all over the world. Stethoscope is one source of nosocomial infection caused by the continuous contact from one patient to another. 70% alcohol and 0.5% chlorine can be used for disinfection. The purpose of the research is to find out the difference in the effectiveness of 70% alcohol and 0.5% chlorine to reduce the amount of germ on the stethoscope’s membrane.Design and Methods: This was an experimental research with the Post Test Only Control Group Design using 18 stethoscopes divided into 3 groups randomly. Group A was the control group (aquabidest), group B were treated with 70% alcohol treatment, and group C was treated with 0.5% chlorine. The research samples were the stethoscopes used to treat patient in Baitul Izah ward of Islamic Hospital of Sultan Agung Semarang. The data on the germ amount was analyzed using Kruskal-Wallis test. Results: There was a significant difference between aquabidest group and 70% alcohol group (p0.05), nevertheless, there was no significant difference between the 70% alcohol group and 0.5% chlorine group ( 0.652). Conclusion: There was no difference in the effectiveness between 70% alcohol and 0.5% chlorine to reduce the number of germ on the stethoscope’s membrane (Sains Medika, 3(1):63-68)
Difference in the Number of Germs Before and After Hand Washing with Triclosan dan Cida-stat® Antiseptic An Experimental Study on Hand Washing of Nurses at Sultan Agung Islamic Hospital
Full text linkBackground:a study conducted among 11 hospitals in DKI Jakarta in 2004 showed that 9.8% in-patient had nosocomial infections, the most common way in which germs spread is through personnel’s hands. Thus, hand washing and antiseptics play a significant role in the prevention of nosocomial infections Triclosan and Cidastat are the two antiseptics used in the Sultan Agung Islamic Hospital. The purpose of this study was to find out the difference in the number of germs on nurse’s hands using Triclosan and Cida-stat.Design and Method: This experimental study using pre and post test control group design used three treated groups; group A (treated with aquabidest), group B (treated with Triclosan), Group C (treated with Cidastat). The samples were palms of 12 nurses for in-patients in the Baitul Syifa ward and Arrijal of Sultan Agung Islamic Hospital.Result: One way anova showed a statistically significant different among the three treated groups with p value of 0.020 (0.05). The paired T test showed a significant difference between Triclosan and Cidastat group.Conclusion: There was no significant different in the number of germ before and after hand washing using Triclosan and Cida-stat antiseptics (Sains Medika, 2(2):163-169)