National University of Ireland, Maynooth

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    Reconhecimento em Dirty Works: A Gestão do Estigma no Trabalho Sexual Recognition in Dirty Works: Managing Stigma in Sex Work

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    Resumo Reconhecimento em Dirty Works: A Gestão do Estigma no Trabalho Sexual Este artigo analisa a gestão do estigma no trabalho sexual, argumentando que esse processo se baseia em anseios por reconhecimento e não somente em expectativas de validação e normalização do trabalho maculado. Ele se embasa nos debates sociológicos contemporâneos sobre dirty works, que visam compreender o impacto das máculas morais nos trabalhadores e as estratégias para gerenciamento de estigmas. A análise é realizada no universo do trabalho sexual no webcamming, um lócus central para compreender demandas por reconhecimento devido à amplitude de sua mácula. O estudo se alicerça em etnografia digital conduzida de 2016 a 2020 e 15 entrevistas em profundidade com trabalhadoras sexuais. Conclui-se que as trabalhadoras buscam desenvolver uma autorrelação positiva e conquistar estima social através do gerenciamento do estigma atribuído a seu labor e a si mesmas, demonstrando narrativamente como o trabalho sexual contribui para seu autodesenvolvimento e possui função social para além da obtenção de renda. Abstract Recognition in Dirty Works: Managing Stigma in Sex Work This paper analyzes the stigma managing in sex work, arguing that this process is based on a longing for recognition and not merely on expectations to validate and normalize the dirty work. It uses contemporary sociological debates about dirty works, which aim to understand the impact of moral taints on workers and the strategies for stigma management. The analysis is developed in webcamming sex labor, a central locus to understand demands for recognition due to the breadth of its taint. The study relies on digital ethnography conducted between 2016 and 2020 and on 15 in-depth interviews with sex workers. The paper concludes that workers aim to develop a positive self-relation and acquire social esteem by managing the stigma attributed to their work and to themselves, demonstrating narratively how sex labor contributes to their self-development and has a social role besides earning income

    Operationalising Article 13 of the Convention on the Rights of Persons with Disabilities the role of assistive technology in ensuring access to justice

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    Access to justice is a determinant of the realisation of all other rights, including the right to health, employment, and education. As persons with disabilities experience increased discrimination and social exclusion and are at higher risk of violence than people without disabilities, it is crucial to ensure access to justice in both the civil and criminal legal spheres for people with disabilities. However, persons with disabilities experience multiple barriers at the macro/structural and individual levels to accessing justice. In light of the significance of access to justice for people with disabilities, and the multiple barriers to accessing justice experienced by those with disabilities, this perspective examines the importance of assistive technology in fulfilling the right to access justice. To fulfill the right of access to the justice system, assistive technologies must be more effectively harnessed to provide equitable access to justice for persons with disabilities

    Higher social class is associated with higher contextualized emotion recognition accuracy across cultures

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    We tested links between social status and emotion recognition accuracy (ERA) with participants from a diverse array of cultures and a new model and method of ERA, the Assessment of Contextualized Emotion (ACE), which incorporates social context and is linked to different types of social interaction across cultures. Participants from the Czech Republic (Study 1) and from 12 cultural groups in Europe, North America, and Asia (Study 2) completed a short version of the ACE, a self-construal scale, and the MacArthur Subjective Social Status (SSS) scale. In both studies, higher SSS was associated with more accuracy. In Study 2, this relationship was mediated by higher independent self-construal and moderated by countries’ long-term orientation and relational mobility. The findings suggest that the positive association between higher social class and emotion recognition accuracy is due to the use of agentic modes of socio-cognitive reasoning by higher status individuals. This raises new questions regarding the socio-cultural ecologies that afford this relationship

    The molecular basis of immunosuppression by soluble CD52 is defined by interactions of N-linked and O-linked glycans with HMGB1 box B

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    Human soluble CD52 is a short glycopeptide comprising 12 amino acids (GQNDTSQTSSPS) which functions as an immune regulator by sequestering the pro-inflammatory high mobility group box protein 1 (HMGB1) and suppressing immune responses. Recombinant CD52 has been shown to act as a broad anti-inflammatory agent, dampening both adaptive and innate immune responses. This short glycopeptide is heavily glycosylated, with a complex sialylated N-linked glycan at N3 and reported O-linked glycosylation possible on several serine and threonine residues. Previously we demonstrated that specific glycosylation features of CD52 are essential for its immunosuppressive function, with terminal a-2,3-linked sialic acids required for binding to the inhibitory SIGLEC-10 receptor leading to T-cell suppression. Using high resolution mass spectrometry, we have further characterized the N- and O-linked glycosylation of Expi293 recombinantly produced CD52 at a glycopeptide and released glycan level, accurately determining glycan heterogeneity of both N- and O-linked glycosylation, and localizing the site of O-glycosylation to T8 with high confidence and direct spectral evidence. This detailed knowledge of CD52 glycosylation informed the construction of a model system, which we analyzed by molecular dynamics simulations to understand the mechanism of recognition and define interactions between bioactive CD52, HMGB1 and the SIGLEC-10 receptor. Our results confirm the essential role of glycosylation, more specifically hyper-sialylation, in the function of CD52, and identify at the atomistic level specific interactions between CD52 glycans and the Box B domain of HMGB1 that determine recognition, and the stability of the CD52/HMGB1 complex. These insights will inform the development of synthetic CD52 as an immunotherapeutic agen

    Opacity and Security Concepts for Discrete Event Systems, Linear Time-invariant Systems, and Max-Plus Linear Systems

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    In this thesis, we review concepts in privacy and security for different classes of dynamical systems, with particular emphasis on opacity and attack detection. Opacity has attracted significant attention in recent years due to its role in tackling privacy-related problems within the area of system and control theory. Opacity is an information-flow property that is concerned with a system ability to hide information from an external observer. This property plays a key role in strengthening resilience against attacks and prevents adversaries from determining if their attacks have succeeded. We begin the thesis by examining opacity in its original setting of discrete event systems (DES) and consider a more recent adaptation for linear time-invariant (LTI) systems. In addition, we also provide some initial thoughts on how opacity might be formulated in the context of max-plus linear systems. Although maxplus systems constitute a subclass of DES, their formal structure resembles that of LTI systems. These models arise in practical setting such as manufacturing systems, communication networks, and railway systems, where synchronization and timing constraints are critical. To ensure the reliable operation of any system, it is essential to design mechanisms that mitigate the effects of malicious behaviour. This thesis also reviews concepts in security with a focus on attack detection, and discusses the connection between opacity and the notion of undetectable attacks

    Racial microaggressions and beyond: the voice and song of the caged bird. An exploration of the lived reality of racism in the lives of Black, Black-white Mixed Ancestry, Asian, and Irish Traveller students during their school-going years in Ireland (1990s-2000s)

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    This study explores racism-racial microaggressions in educational contexts from the perspective of Black, Black-white Mixed ancestry, Asian, and Irish Traveller Students. The lacuna in the literature around racialised and minoritised students' experiences of racism in post-primary contexts foregrounded this research. Drawing on semi-structured interviews with ten individuals, the study uses a multi-theory and multi-qualitative method (bricolage) approach to examine the lived experiences of these students at predominantly white educational institutions (PWIs) in Ireland. Critical race theory (CRT) and critical counter-narrative are employed to challenge the master narrative that ‘Ireland is not a place of racism’ and to decentre whiteness and the dominant perspectives and realities rooted therein, which are valorised and given eminence in society. This study foregrounds and privileges the voice, experiential realities, and subjugated knowledges of racialised and minoritised individuals, which are often dismissed and trivialised in education scholarship and other domains. Research participants share the stark reality that racism in all its forms is a very real and harrowing part of their lived experience. The ten study participants provide retrospective and introspective counter-narratives that reveal the dehumanisation, marginalisation, violent erasure, ostracisation, criminalisation, discrimination, and isolation suffered at the hands of members of the dominant group. Participants also reported deafening silences, a fragile race avoidance, and a sweeping under-the-rug approach adopted by school personnel when it came to addressing issues of race and racism. The combined impact of explicit racism and the more subtle, insidious racial microaggressions and the associated effects was reported to be severely detrimental, with long-lasting and far-reaching pernicious repercussions. Study participants offer recommendations for transformative action that policymakers, school leadership, and the teaching body at large can adopt to advance racial equity. Using Huber and Solorzano’s (2020) tree model as a basis, this investigation also illustrates the ways that ideologies inherent in white supremacy serve as roots that produce and justify racism-racial microaggressions. Ultimately, the study calls for a denuding and dethroning of the deification of white supremacy and whiteness for racial justice to prevail in our classrooms, schools, and society at large. An examination and interrogation of whiteness, particularly in predominantly white settings, is a foundational prerequisite for reform at a societal level

    Unique osteological evidence for human-animal gladiatorial combat in Roman Britain

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    The spectacle of Roman gladiatorial combat captures the public imagination and elicits significant scholarly interest. Skeletal evidence associated with gladiatorial combat is rare, with most evidence deriving from written or visual sources. A single skeleton from a Roman cemetery outside of York where gladiators arguably were buried presented with unusual lesions. Investigation, including comparative work from modern zoological institutions, has demonstrated that these marks originate from large cat scavenging. Thus, we present the first physical evidence for human-animal gladiatorial combat from the Roman period seen anywhere in Europe

    Gradient test to assess homogeneity of probabilities in discrete-time transition models with application in agricultural science data

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    Longitudinal studies in discrete or continuous time involving categorical data are common in agricultural sciences. Transition models can be used as a means to analyse the resulting data, especially when the aim is to describe category changes over time, as well as to accommodate covariates due to experimental design. Here we focus on discrete-time models, for which it is critical to assess whether the underlying process is stationary or not. Tests based on likelihood procedures are very useful, and here we propose the Gradient test to assess stationary, or homogeneity of transition probabilities. We carried out simulation studies to evaluate the performance of the proposed test, which indicated a good performance regarding type-I error and power when compared to other classical tests available in the literature. As motivation we present two studies with agricultural data, the first one applied to entomology with nominal responses and the second application refers to the degree of injury in pigs. Using our proposed test, stationarity and non-stationarity were verified respectively in the applications. Since the gradient test to assess stationarity has a simplified structure when compared to other tests, it is therefore a useful alternative when carrying out inference in these types of models

    Enhancing Teaching, Learning and Curriculum Design Through Education Frameworks: Executive Summary

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    Inspireurope + Insights Researchers at Risk as Human Rights Defenders

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    Support for human rights defenders is a long-established part of the European Union’s human rights external relations policy. The purpose of this brief is to highlight that a significant number of researchers at risk are HRDs, whether by the nature of their academic work, extramural advocacy work, or expressive activities

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