Althea Medical Journal
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Five-Year Data of Clinical Characteristics and Laboratory Findings of Hospitalized Hemophilic Patients in Dr. Hasan Sadikin General Hospital
Get PDFBackground: Hemophilia A has the highest incidence, more than 80% of 172.323 cases worldwide in 2012. It is stated that clinical characteristics of hemophilia A is worse than others, so it is required to prove and to know further about the clinical characteristics and severity likelihood in all hemophilic patients in order to prevent re-bleeding and re-injury and also for a better medical response.Methods: A retrospective cross-sectional study was carried out to 43 medical records of hospitalized hemophilic patients from 2009 to 2013 in Dr Hasan Sadikin General Hospital. The inclusion criteria were a complete patient identity (name, age, sex), written chief complaint, complete physical examination (bleeding, edema, hematoma, hemarthrosis, anemic symptoms) and laboratory test results (factor level, hemoglobin, hematocrit, platelet and Activated Partial Thromboplastin Time). The data was collected from August‒October 2014, analyzed and presented using frequency distribution.Results: Most of the patients were 5-10 years old, male and had hemophilia A. The most common complaint was external bleeding, followed by edema. From 43 patients, 38 (88%) cases were classified as severe factor deficiency, had mild to severe anemia, however the platelet count in most of the cases was in normal value. About 91% cases had prolonged Activated Partial Thromboplastin Time in moderate to severe level.Conclusions: Similar with other studies worldwide, most of the hospitalized hemophilic patients have hemophilia A. Most of the patents has moderate to severe bleeding with laboratory test result between moderate to severe level as well. [AMJ.2016;3(4):605–9
Relationship between Menstrual Profile and Psychological Stress with Dysmenorrhea
Get PDFBackground: Dysmenorrhea or menstrual cramps is the most common menstrual complaint among reproductive women in developing countries. The prevalence of dysmenorrhea is ranged from 19–91%. Many studies showed that factors associated with dysmenorrhea include a younger age, nulliparity, family history of dysmenorrhea, prolonged menstrual duration, high menstrual flow, psychological factors, and lifestyle. The objective of this study was to compare female medical students with dysmenorrhea and without dysmenorrhea regarding menstrual profile and psychological stress, also to examine the relationship between psychological stress and dysmenorrhea specifically..Methods: This cross-sectional study was conducted among 136 fourth year female medical students of Universitas Padjadjaran. It used a structured, self-assessment, validated, and reliable questionnaire, such as Wong Baker Faces® Pain Rating Scale in combination with Numeric Scale Pain, and Depression, Anxiety, Stress Scale (DASS-42). Then, the descriptive data analysis and chi-square hypothesis test were used to explore the relationship between the severity of psychological stress and the presence or severity of dysmenorrhea.Results: Family history of dysmenorrhea had a strongest relationship with dysmenorrhea. Nevertheless, there was no statistically significant interaction between the severity of stress and the presence of last menstrual cramps (p 0.745, Odd Ratio 1.15, 95% Confidence Interval 0.5–2.66). However, a positive relationship between the severity of stress and dysmenorrhea in last menstruation was found in this study (p 0.033, Odd Ratio 3.69, 95% Confidence Interval 1.06–12.8).Conclusions: The severity of stress and dysmenorrhea in last menstruation is related among the subjects with dysmenorrhea. [AMJ.2016;3(3):382–7]DOI: 10.15850/amj.v3n3.884
Comparison of Hip Abductor and Adductor Muscle Strength in Taekwondo and Non-taekwondo Practitioners
Get PDFBackground: Taekwondo is an empty hand combat that entails the use of the whole body. Spinning and turning kicks are the proper way of kicking in taekwondo which allow one to maximally perform the hip abductor and adductor muscles simultaneously. To measure the hip abductor and adductor muscles of Taekwondo and Non-taekwondo practitioners, Hand-Held Dynamometer (HHD) is used. This study aimed to compare the hip abductor and adductor muscles strength in Taekwondo and Non-taekwondo practitioners.Methods: This analytical study of paired continuous variable was conducted using cross-sectional method. Thirty-two subjects were examined from September−October 2014 at the skills laboratory of Faculty of Medicine, Universitas Padjadjaran. Sixteen of them were Taekwondo practitioner and the other sixteen of them were Non-Taekwondo practitioner. Gender, weight, height, Body Mass Index (BMI) and maximum strength of hip abductor and adductor muscles were examined by using Hand-Held Dynamometer (HHD).Results: Off all physical characteristics being examined, it showed that the p-values were above 0.5. The independent t-test showed that the average strength of hip abductors and adductors muscle in Taekwondo and Non-taekwondo practitioners were significantly different in which the both p-values were less than 0.05.Conclusions: The maximum strength of hip abductor and adductor muscles of Taekwondo and Non-taekwondo practitioners were significantly different. The strength of hip abductors and adductors muscles is greater in Taekwondo practitioners compared to Non-taekwondo practitioners. [AMJ.2016;3(3):392–5]DOI: 10.15850/amj.v3n3.88
The Effect of Breadfruit Leaves Infusion on Acute Renal Failure Rat model Abstract
No full textBackground : Empirically, breadfruit (Artocarpus altilis) leaf has been used as traditional medicine for several diseases, such as acute renal failure. This research is aimed at finding the effects of breadfruit leaf infusion on blood creatinine levels in rats to model acute renal failure.Methods : This research is an experimental study, using 30 male wistar rats, weighing 150–250 g, divided into 5 groups. The first group is a negative control and the second group is a positive control. Groups 2–5 were induced with Gentamicine and peroxicam for 7 days, and then groups 3–5 given infusion of breadfruit leaf in different doses for 7 days, and then blood creatinine levels were tested at the 15th day. This data was analyzed using a multiple comparison Dunnett T3 test because this data is not homogenous. This research was done in pharmacology laboratorium universitas padjadjaran from Oktober–November 2012.Result : Bases on average creatinine levels of 0.62, 0.87, 0.98, and 0.87 mg/dL observed for the diffetent groups, it was statistically show that significantly different creatinine levels, differing by 0.038 (p < 0.05) were observed for the control group and the group which was given an infusion of breadfruit leaf.Conclusion : It can be concluded that infusions of breadfruit leaf do have an effects on blood creatinine levels in acute renal failure.Key words : acute renal failure, breadfruit leaf, creatinine DOI: 10.15850/amj.v2n4.52
Gestational Age Conformity between New Ballard Score and Last Menstrual Period in Newborn with Respiratory Distress Syndrome
Get PDFBackground: Gestational age is required to determine diagnosis and optimal management of newborns. The gold standard for gestational age determination is the first day of last menstrual period (LMP). However, not all mothers remember their LMP. Another method for gestational age determination after birth is the New Ballard Score (NBS). This method measures gestational age using two main components, namely neorumuscular and physical maturity. In premature infants, surfactant deficiency leads to hypoxia which eventually leads to neuromuscular disorders. This situation may cause younger gestational age estimation when using NBS. The objective of this study was to analyze the conformity between NBS and LMP in determining gestational age in newborns with respiratory distress syndrome (RDS).Methods: A cross-sectional study was conducted on 35 newborns with RDS that were recorded in 2012 database in Dr. Hasan Sadikin General Hospital Bandung. Data on the date of birth, LMP, NBS soon after birth, sex, birth weight, type of delivery and diagnosis were collected and analyzed statistically using Wilcoxon test.Results: The study showed that there was a significant difference (p<0.05) between gestational age determination done using NBS soon after birth and LMP in newborns with RDS.Conclusions: Gestational age determination based on NBS soon after birth does not conform the LMP in newborns with RDS. [AMJ.2016;3(3):401–4]DOI: 10.15850/amj.v3n3.88
Characteristics of Thyroiditis Patients in Dr. Hasan Sadikin General Hospital in 2009–2013
Get PDFBackground: It is reported that thyroid diseases affect around 200 milion people in the world. One of them is thyroiditis that may cause the risk of cancer. Moreover, thyroiditis can also cause hormonal disorders, such as hypothyroid and hyperthyroid. It is assumed that thyroiditis has distinctive clinical characteristics. The aim of this study was to evaluate the characteristics of thyroiditis based on age, gender, location, and clinical features of the patient.Methods: The study was conducted using descriptive-retrospective method. The data were collected from patients’ medical records through total sampling from January 2009 to Desember 2013 in Dr. Hasan Sadikin General Hospital, Bandung.Results: It was found 35 cases of thyroiditis. Based on the histopathological type, the most frequently found thyroiditis was Hashimoto’s thyroiditis. Based on age, thyroiditis mostly affected people at age 41–60 years old. Based on the gender, thyroiditis mostly affected female and the location of lesions were bilateral. The majority clinical features of patients were hypothyroid in Hashimoto’s thyroiditis, hyperthyroid in acute thyroiditis, and normothyroid in sub-acute granulomatous thyroiditis.Conclusions: Based on age, gender, and the location, the majority type of thyroiditis did not show specific characteristics. However, thyroiditis showed specific characteristics based on the clinical features of patient. [AMJ.2016;3(1):49–53]DOI: 10.15850/amj.v3n1.70
Correlation between Cognitive Functions and Activity of Daily Living among Post-Stroke Patients
Get PDFBackground: Cognitive impairment is one of the most common post-stroke complications; however, neither patients nor health professionals are often aware of this complication. The impact of cognitive impairment on quality of life is reflected through basic activity daily living (bADL) and instrumental activity daily living (IADL). Prior studies concerning the correlation between cognitive impairment and activity daily living has shown contradictive results. This study was conducted in order to analyze the correlation between the cognitive functions and activity daily living in post stroke patients at Dr. Hasan Sadikin General Hospital.Methods: This cross-sectional study was carried out to 23 post-stroke patients from September–November 2015. Samples were collected through consecutive sampling at Dr. Hasan Sadikin General Hospital. Mini Mental State Examination (MMSE) was used to assess the cognitive functions and Lawton and Brody Scale to assess both bADL and IADL. Spearman correlation was selected to analyze the existing correlation between each cognitive domain and activity daily living.Results: Spearman statistical correlation showed an insignificant correlation between the cognitive functions and bADL (r2=0.181, p=0.408) and a significant correlation with IADL was obtained (r2=0.517, p=0.03). The only cognitive domain positively correlated with IADL was orientation to time and verbal recall.Conclusions: There is a correlation between cognitive functions and IADL among post-stroke patients at Dr. Hasan Sadikin General Hospital. [AMJ.2016;3(3):329–33] DOI: 10.15850/amj.v3n3.87
Knowledge and Attitude of Senior High School Students toward Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome
Get PDFBackground: Indonesia has experienced more than 25% rise of Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome (HIV/AIDS) incidence. One of the provinces mostly affected is West Java. Proper knowledge of HIV/AIDS can develop attitude and practice to prevent the spread of HIV/AIDS, and in effect, its incidence. This study was conducted to describe the knowledge and attitude of Senior High School (Sekolah Menengah Atas, SMA) students toward HIV/AIDS.Methods: This descriptive study was conducted using a cross-sectional method and used secondary data with total sampling technique, from Jatinangor Cohort Research Team of the Faculty of Medicine, Universitas Padjadjaran. The samples were obtained by stratified cluster random sampling. Two hundred and seventy seven students’ knowledge and attitude were assessed in Senior High School in Jatinangor, on May 2013Results: Senior High School students in Jatinangor mostly (50.2%) had a poor level of knowledge, yet 51.3% positive attitude toward HIV/AIDS. There were still misconception regarding transmission media of HIV/AIDS and mode of transmission HIV/AIDS. Information source on HIV/AIDS were teachers (96.4%), followed by television (93.5%), internet (86.6%), friends (84.8%), health workers (69.7%), newspapers (62.1%), parents (61%), magazines (55.2%), and radio (33.2%).Conclusions: Although most of the Senior High School students in Jatinangor have a poor level of knowledge, they have a positive attitude toward HIV/AIDS. The main information source on HIV/AIDS is teacher. [AMJ.2016;3(1):73–8] DOI: 10.15850/amj.v3n1.71
Health Promotion Activities in Bandung Public Health Centre (Puskesmas)
Get PDFBackground: Health promotion is one of Public Health Centre (Pusat Kesehatan Masyarakat, Puskesmas) essential health effort able to increase community health status. The purpose of this study was to describe health promotion activities in Bandung Public Health Centre (Puskesmas).Methods: This study was a cross sectional descriptive study using questionnaire as data collection instrument. The questionnaires were distributed to 24 Puskesmas in Bandung that were selected randomly using simple random sampling method. The process of questionnaire filling was performed by health promotion officer after informed consent was done. The variables were basic health promotion strategies, health promotion supports, health promotion in health facility and health promotion in community.Results: Most of the Puskesmas showed that basic health promotion strategies, health promotion in health facility and health promotion in community were already done. Support media that was mostly used was printed media while lectures was the most used method. Human resources practitioner and coordinator of health promotion were dominated by mid level health workers consists of midwife and nurse. This study showed that the majority of health promotion coordinator had underwint training and certificate related to health promotion. The availability of funds were possessed by 13 out of 24 sample. While, health promotion guideline were possessed by less than half of the sample.Conclusions: Health promotion is done in almost all sample. There is lack of health promotion support in the form of the availability of funds and guideline of health promotion method. [AMJ.2016;3(3):459–67]DOI: 10.15850/amj.v3n3.86
Antibacterial Effect of Pulsatilla chinensis towards Staphylococcus aureus, Shigella dysenteriae, and Salmonella typhi
Get PDFBackground: Pulsatilla (P.) chinensis is a kind of traditional Chinese medicine (TCM) that has antibacterial effect. It is used to treat diarrhea, dysentery, and other diseases. The P. chinensis is composed of some potent antibacterial substances including protoanemonin, saponin, oleanolic acid. The study aimed to determine the antibacterial effect of P. chinensis towards staphlococcus aureus, Shigella dysenteriae, and Salmonella typhi.Methods: This was an experimental descriptive study that was conducted in 2014 using two methods, diffusion and dilution method. In diffusion method, 5 holes were made on the agar that bacteria were growing and different concentrations of P. chinensis infusion were placed in different hole. The inhibitory effect was measured by the inhibition zone. In dilution method, 8 test tubes with decreasing concentration of P. chinensis infusion were mixed with the bacteria suspension and Mueller Hinton Solution. The minimal inhibitory concentration (MIC) was measured by the last clear test tube. The test tube with solution that showed absence of bacteria on culture indicated the minimal bactericidal concentration (MBC).Results: In diffusion method, P. chinensis infusion showed inhibitory effect towards S. aureus and bacteriostatic effect towards S. dysenteriae and S. typhi. In dilution method, there was no antibacterial activity detected.Conclusions: P. chinensis infusion has inhibitory effect on S. aureus and bacteriostatic effect on S. dysenteriae and S. typhi. [AMJ.2016;3(2):292–5]DOI: 10.15850/amj.v3n2.46