International Journal of Integrated Health Sciences
Not a member yet
95 research outputs found
Sort by
Correlation between Handgrip Strength, Mobilization Function, Physical Activity Level, and Muscle Mass in Community-Dwelling Elderly in Bandung, West Java Province, Indonesia
Get PDFObjective: To investigate correlation between handgrip strength, mobilization function, and physical activity level (PAL), and muscle mass in community-dwelling Indonesian elderly.Methods: This was a cross-sectional study 193 subjects aged 60–90 years. Handgrip strength was measured using handgrip dynamometer while the mobilization function was assessed by performing gait speed test. Global Physical Activity Questionnaire (GPAQ) was used to assess the participant’s PAL and Bio Impedance Analyzer was used to measure the participant’s muscle mass based on skeletal mass index.Results: Significant positive correlations were discovered between handgrip strength and walking speed (rs. 0.501; p<0.001), PAL (rs. 0.153; p=0.003), and muscle mass (rs. 0,452; p<0.001).Conclusion: Stronger handgrip determines greater mobilization function, physical activity level, and bigger muscle mass in community-dwelling Indonesian elderly. Keywords: Gait speed, handgrip strength, muscle mass, physical activity DOI: 10.15850/ijihs.v6n1.104
Characteristics of Cerebrospinal Fluid in Tuberculous Meningitis Patients with Hydrocephalus
Get PDFObjective: To describe cerebrospinal fluid (CSF) characteristics in tuberculous meningitis (TBM) with hydrocephalus patients as diagnostic criteria of TBM.Methods: A cross-sectional using retrospective method was applied in this study by obtaining medical records of TBM with hydrocephalus patients that were treated at Department of Neurosurgery Dr. Hasan Sadikin General Hospital, Bandung from January 2014–September 2016. Results: Sixty one records were included in the study. Patient characteristics such as age, gender, and CSF laboratory features such as color and clarity, cells and differential count, protein, and glucose were recorded and descriptively analyzed. The majority of CSF macroscopic appearance was seen to be clear (88%) and colorless (88%). Median for CSF cell count was 25 cells/mm3 with lymphocyte predominance (median: 76%). Increased protein from normal value range was seen in CSF (median: 50 mg/dL) while the mean for CSF glucose in this study remained in its normal value range (mean: 58.9±26.68 mg/dL) with lower CSF to blood glucose ratio (mean: 0.41±0.27).Conclusions: Clear CSF with colorless appearance, lymphocyte pleocytosis, high protein level, and low CSF glucose as well as blood glucose ratio remain typical CSF characteristics of TBM patients found at the Department of Neurosurgery, Dr. Hasan Sadikin General Hospital, Bandung. Keywords: Cerebrospinal fluid, hydrocephalus, tuberculous meningitis DOI: 10.15850/ijihs.v6n2.112
Associations between Nutrition Knowledge, Vitamin C Intake, Nutritional Status, and Blood Pressure among Elderly with Hypertension in Klaten, Central Java, Indonesia
Get PDFObjective: To analyze the correlation between nutrition knowledge, vitamin C intake, and nutritional status on blood pressure among elderly with hypertension.Methods: This was a cross-sectional study with purposive random sampling which was conducted from April to May 2017. This study included one hundred twenty-five elderly subjects with hypertension who met the inclusion criteria (17 males and 108 females), aged ≥60 years, who lived in the work area of Juwiring Public Health Center in Klaten district, Central Java, Indonesia. The data were analyzed statistically by using normality, correlation, and multiple linear regression tests. Results: The results of the correlation test showed that there was a correlation between nutrition knowledge (p=0.011), vitamin C intake (p=0.012), nutritional status (p=0.048), and blood pressure hypertension in elderly based on the results of multiple linear regression. All data were analyzed statistically using Spearman correlation test to examine the distributed data. A significant correlation was found between nutrition knowledge, vitamin C intake, and nutritional status (p<0.05) using multiple linear regression (p<0.05). A normality test using the Kolmogorov-Smirnov test resulted in normal residue with p-value 0.000. The results showed that the regression analysis could be used to predict the blood pressure.Conclusion: There was a correlation between nutrition knowledge and blood pressure of hypertension in elderly. There was a correlation between vitamin C intake and a blood pressure of hypertension in elderly. There was a correlation between nutritional status and a blood pressure of hypertension in elderly.Keywords: Blood pressure, elderly hypertension, nutrition knowledge, nutritional status, vitamin C intake DOI: 10.15850/ijihs.v6n1.111
Triamcinolone Acetonide and 5-Fluorouracil Intralesional Combination Injection in Keloid Treatment
Get PDFObjective: To evaluate the effectiveness of steroid and 5-fluorouracil (5-FU) injection combination for keloid management.Methods: A 22-year-old female patient was presented with recurrent skin lesions. The skin lesions first appeared 10 years prior to consultation, had been surgically excised, and were given triamcinolone acetonide injection. However, no improvement was observed. A decision was made to use and evaluate treatment using an intralesional 4 mg (0.1 ml of 40 mg/ml) triamcinolone acetonide and 45 mg (0.9 ml of 50 mg/ml ) 5-FU injection combination for 5 weeks.Results: Clinical improvements were observed in the third week as the lesions softened and pruritic sensation dinimished. At the end of the fifth week, improvements in the form of keloid lesion flattening and size reduction were observed.Conclusions: Intralesional injection using a combination of triamcinolone acetonide and 5-fluorouracil is effective for keloid lesion treatment.Keywords: 5-fluorouracil, intralesional injection, keloid, triamcinolone acetonide DOI: 10.15850/ijihs.v5n1.95
Quality of Life in Thalassemia Major Patients: Reliability and Validity of Indonesian Version of TranQol Questionnaire
Get PDFObjective: To determine the validity and reliability of TranQol questionnaire that has been translated into Indonesian to be used in Indonesian thalassemia major patients. The quality of life problems among these patients can be detected earlier because TranQol is more precise compared to the Pediatric Quality of Life Inventory (PedsQLTM), World Health Organization Quality of Life Instruments (WHOQOL), and SF-36 Questionaire.Methods: This study was conducted in Bandung, Indonesia from October 2015 to March 2016 and used a standard “forward-backward” translation procedure. It involved 60 adults and 73 children who are thalassemia major patients, and 71 parents of patients in Dr. Hasan Sadikin General Hospital. TranQol was processed through forward and backward translation approach and evaluation was conducted by the TranQol author. After the translation process, a cognitive debriefing was performed and the translated TranQol was tested to all subjects.Results: Cronbach’s alpha >0.7 was used for all TranQol categories. Front validity and content validity testing was performed. The internal validity results showed that some questions were not valid.Conclusions: TranQol reliability in Indonesian language for every category is good. Validity for TranQol in Indonesian language shows that the translated TranQol is not quite suitable that it still cannot be used. Keywords: TranQol Indonesia, validity Indonesia, reliability Indonesia DOI: 10.15850/ijihs.v5n2.101
Relationship between Physical Activity, Anthropometry, and Forced Expiratory Volume in One Second with 6-Minute Walk Distance in Elderly
Get PDFObjective: To examine the correlation between physical activity using the Global Physical Activity Questionnaire (GPAQ), anthropometry (body mass index/BMI), and forced expiratory volume in one second (FEV1) value with six-minute walk distance in healthy community-dwelling elderly.Methods: A cross-sectional design study with consecutive sampling was conducted. This study included sixty nine participants (30 males and 39 females), aged ≥60 years who lives at Batununggal region in Bandung, Indonesia. The data was analyzed statistically by using normality, correlation, and multiple regresion tests. Results: The results showed that there was a correlation between six-minute walk distance and BMI in females (p=0.006), and FEV1 value in males (p=0.010). No significant correlation was found between GPAQ value and six-minute walk distance in females (p=0.4074) and in males (p=0.0926). Conclusions: There was a correlation between anthropometry and FEV1 value with six-minute walk distance in healthy elderly. There was no significant correlation between physical activity and six-minute walk distance. Keywords: Anthropometric measurement, FEV1, physical activity, six-minute walk distance DOI: 10.15850/ijihs.v5n1.96
Sapodilla (Manilkara zapota) Broth as an Alternative Media for Candida albicans
Get PDFObjective: To determine whether sapodilla can be used to grow Candida albicans. Among all the high galactose and arabinose content fruits, the sapodilla was chosen because it is available year round and can get easily in market. Other than that, it also contains vitamins, calcium and phosphorus which are very useful for fungi growth.Methods: This study used an experimental study as a method of research. The researcher culture Candida albicans on the experimental sapodilla media and identifies the morphology of the fungi by using Gram staining method. The experiment will be replicated two times to get accurate result. The procedure of this experiment constitute of sapodilla media preparation, sapodilla media observation, organism preparation, planting and incubation, observation of fungal colonies and identification of the fungi.Results: In 0%, there was no fungal growth at all. In 5%, there was mild density of fungal colonies. In 10%, there was moderate density of fungal colonies and in 15% the fungal grew with very dense colonies.Conclusions: Sapodilla (Manilkara zapota) broth can be used as an alternative media for Candida albicans.Keywords: Alternative media, Candida albicans, Sapodilla brothDOI: 10.15850/ijihs.v5n1.96
Morphological Changes of Cisplatin-resistant Human Breast Cancer MCF-7 Cell Line
Get PDFObjective: To evaluate morphological changes of breast cancer cell line MCF-7 following the development of acquired resistance towards cisplatin. Resistance towards anticancer agents still plays an important role in the breast cancer chemotherapy failure.Methods: The cisplatin resistant subline MCF-7/CisR was developed in-vitro by cultivating the parental cell line cisplatin-sensitive MCF-7 with raising concentration of cisplatin (from 0.01 to 2.3 µM) for four months. The cell morphology was observed by giemsa staining. Results: The resistance was shown by the increase of IC50 by 9 folds on MCF-7/CisR compared to the initial IC50 value of MCF-7. The change in cisplatin cytotoxic potency on the resistant cell line was accompanied by the morphological modification, including the enlargement of cell size, the increase of nucleus and cytoplasm ratio, and the increase of the number of microvesicular and cytoplasmic granules.Conclusions: This result has supported the underlying mechanism of cisplatin resistance, including the ability of the cells to decrease intracellular cisplatin concentration and repair DNA damage effects
Correlation between Degree of Gibbus Angulation, Neurological Deficits, and Pain in Spondylitis Tuberculosis Patients
Get PDFObjective: To analyze the correlation between the degree of angulation and neurological deficits as well as pain in spondylitis tuberculosis (TB) patients.Methods: This observational-analytic study included bivariate analysis on data collected from the medical records of patients with presented with spondylitis TB to Dr. Hasan Sadikin General Hospital, Bandung outpatient clinic from January 2014 to December 2015. The variables were the degree of gibbus angulation, neurological deficits, and pain.Results: The study showed significant positive correlation between gibbus angulation and sensory neurological deficits (r=0.375; p=0.009) and there was significant positive correlation between gibbus angulation and pain (r=0.638, p=0.000). The study showed an insignificant correlation between gibbus angulation and motoric neurological deficits (r=0.125; p=0.525).Conclusions: There is a significant correlation between the degree of gibbus angulation and pain as well as sensory neurological deficits. Meanwhile, no significant correlation is found between the degree of gibbus angulation and motoric neurological deficits.Keywords: Gibbus angulation, neurological deficits, pain, spondylitis tuberculosis DOI: 10.15850/ijihs.v5n2.104
Cognitive Function Profile of Post-Stroke Patients
Get PDFObjective: To discover cognitive function profile of post-stroke patients undergoing rehabilitation to inform rehabilitation professionals in planning for a program and provide services that meet the patient’s need. Methods: This study was a descriptive cross-sectional study involving 32 post-stroke patients undergoing rehabilitation at the Physical Medicine and Rehabilitation clinic of Dr. Hasan Sadikin General Hospital Bandung in August–September 2014. An examination was conducted using the Mini Mental State Examination (MMSE) to obtain the cognitive function profile of post-stroke patients. Results: The results showed that almost all post-stroke patients undergoing rehabilitation had normal cognitive functions (93.8%), only few patients had probable cognitive impairment (6.2%). Probable cognitive impairment were found in male and female patients who were in the age range of 50–60 years who were elementary school graduates and in the sub acute phase of stroke. Conclusions: Almost all post-stroke patients undergoing rehabilitation have normal cognitive functions, only minority of patients have probable cognitive impairment, and there are no patients with definite cognitive impairment. Keywords: Cognitive function, education, rehabilitation, stroke DOI: 10.15850/ijihs.v5n1.96