Qazvin University of Medical Sciences
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Flavonoid GL-V9 induces apoptosis and inhibits glycolysis of breast cancer via disrupting GSK-3β-modulated mitochondrial binding of HKII(ارائه ژورنال کلاب)
طراحی و بهینه سازی روش ردیابی و تشخیص مستقیم استافیلوکوکوس اورئوس در مواد غذایی با استفاده از روش Nested PCR(فایل تصویب عنوان)
ارائه چارچوب مشارکت سالمندان در مراقبت های بهداشتی اولیه در مجتمع های سلامت شهر تبریز97-98(فایل دفاع نهایی)
Challenges in The Clinical Education Environment during the COVID-19 Outdreak: the Experiences of Medical Students
Program development using intervention mapping in primary healthcare settings to address elder abuse: A randomized controlled pilot study
بررسی شاخص های زمانی اورژانس پیش بیمارستانی در دانشگاه علوم پزشکی قزوین و ارائه راهکارهای بهبود (فایل ارائه ژورنال کلاب)
بررسی میزان ابتلا به بیماری کووید 19 و ارتباط آن با رعایت پروتکل های بهداشتی در دو گروه صنایع شوینده و دفاتر خدمات الکترونیک درشهرستان البرز (فایل ارائه تصویب عنوان)
Randomized double blind clinical trial evaluating the Ellagic acid effects on insulin resistance, oxidative stress and sex hormones levels in women with polycystic ovarian syndrome
Abstract
Objective: The design of this study was due to the report of the antioxidant properties of Ellagic acid (EA) for its evaluation on the Insulin resistance (IR), oxidative stress and sex hormones levels in women with polycystic ovarian syndrome (PCOS).
Methods: In this randomized, double-blind, placebo-controlled clinical trial, 60 patients were recruited. Patients were randomly allocated consumed a capsule containing 200 mg of EA per day (n = 30) or placebo (n = 30) for 8 weeks. The fasting blood sugar (FBS), insulin, IR, total cholesterol (TC), triglycerides (TG), low density lipoprotein (LDL), high density lipoprotein (HDL), total antioxidant capacity (TAC), Malondialdehyde (MDA), C-reactive protein (CRP), Tumor necrosis factor-alpha (TNF-α), sex hormones and anti-mullerian hormone (AMH) were measured at the beginning and end of the study.
Result: At the end of the study, the mean of FBS, insulin, IR, TC, TG, LDL, MDA, CRP, TNF-α, total testosterone, prolactin and AMH were significantly decreased in the intervention group compared to the placebo group (P 0.05).
Conclusion: EA supplementation can be helpful as a diet supplement in women with PCOS through improvement in insulin resistance. This supplement may be used to reduce metabolic disorders in women