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Effect of an Eight-week High-intensity Interval Training Program on Serum Cardiac Troponin I Level of Streptozotocin-induced Diabetic Rats
Background One of the complications of diabetes, as a chronic metabolic disorder, is cardiovascular diseases.
Objective This study aims to investigate the effect of an eight-week High-Intensity Interval Training (HIIT)
program on serum Cardiac troponin I (CtnI) level in streptozotocin-induced diabetic rats.
Methods In this experimental clinical trial, 30 rats were randomly assigned into three groups of healthy
Control (C), Diabetic (D), and diabetic+training (D+T). The third group performed the training which included
a treadmill running at an intensity of 85%-90% of maximum speed in 6-12 sessions of 2 min for 8
weeks, 5 days per week. Blood glucose level and high-sensitive CtnI levels were measured 48 hours after
the last training session and 12 hours of fasting. One-way ANOVA and Tukey’s test were used to analyze
the collected data, considering a significance level of P<0.05.
Findings The induction of diabetes caused a significant increase in blood glucose (P=0.01) and high-sensitive
CtnI (P=0.01) levels in the D group. Also, a significant difference was observed in the blood glucose
level of D+T group compared to the D group (P=0.001). The CtnI level also slightly reduced (11%) in the
D+T group compared to the D group, but it was not statistically significant (P=0.591).
Conclusion he HIIT program can reduce the fasting blood glucose and increase the serum level of highsensitive
CtnI to some extent in diabetic rats; therefore, it can be an appropriate strategy for diabetics.
However, there is a need for more studies in this area
Assessing the General Health Indicators Predicting Marital Satisfaction in Older Couples
Background Due to the increasing life expectancy and aging population, attention to general health and
marital satisfaction of older people can provide an opportunity to improve their living conditions.
Objective This study aims to assess the general health indicators of older couples to predict their marital
satisfaction.
Methods This descriptive cross-sectional study was conducted on 110 older couples (men and women)
living in Qazvin, Iran who were selected using two-stage cluster sampling technique. A demographic
form, General Health Questionnaire (GHQ) and The ENRICH Marital Satisfaction Scale (EMSS) were used
to collect data. Descriptive statistics and multivariate regression analysis were used for data analysis.
Findings The Mean±SD age of older women and Men±SD was 64.15±5.46 years and 67.68±6.93 years,
respectively. Their Mean±SD EMSS score was reported 109.72±12.58. Multivariate analysis showed that
gender (β=0.169, P=0.050), age (β=0.097, P=0.567), age of marriage (β=0.214, P=0.002), somatic symptoms
(β=0.233, P=0.013), anxiety/insomnia (β=0.227, P=0.008), social dysfunction (β=0.326, P<0.001),
and depression (β=0.356, P<0.001) could significantly predict marital satisfaction.
Conclusion Different dimensions of general health can affect marital satisfaction of older couples. Therefore,
interventions in these domains and the promotion of general health level can lead to increased
marital satisfaction and, consequently, quality of life in the elderly
Association of White Blood Cell Count With Metabolic Syndrome in Obese Men and Women
Background Despite the widespread obesity epidemic in the world, not all obese people are equally
susceptible to the complications of obesity. Inflammatory factors play an important role in the complications
of obesity.
Objective This study aims to evaluate the association of White Blood Cell (WBC) count with metabolic
syndrome in overweight/obese men and women.
Methods This cross-sectional study is a part of the Qazvin Metabolic Disease Study (QMDS) conducted
in 2010 in Qazvin, Iran. Participants were 622 obese people with a body mass index (BMI) ≥25 kg/m2,
recruited from the QMDS. Metabolic syndrome was defined according to the Adult Treatment Panel III
criteria. Data were analyzed using Chi-square test, t-test, and logistic regression analysis (to evaluate the
relationship between WBC count quartiles and metabolic syndrome).
Findings Prevalence of metabolic syndrome was not significantly different between men and women. In
men, prevalence of metabolic syndrome and its components were not different between WBC quartiles.
In women, 32.2% and 60.5% had metabolic syndrome in the first and fourth quartiles of WBC count,
respectively (P<0.001). Moreover, the prevalence of insulin resistance was higher in fourth quartile compared
to the first quartile (47.7% vs. 25.6%, P<0.001). After controlling the effects of age and BMI factors,
the risk of metabolic syndrome in the fourth quartile of WBC count remained significant in women
(OR=2.56, P<0.01).
Conclusion Association of WBC count with metabolic syndrome is significant in obese women compared
to obese men
Effect of health promoting lifestyle education on health promoting behaviors of postmenopausal women: A clinical trial study
Decreased insulin resistance in diabetic patients by influencing Sirtuin1 and Fetuin-A following supplementation with ellagic acid: a randomized controlled trial
Background: The benefcial efects of polyphenols have been reported. This study aimed to investigate the efect of
oral Ellagic acid (EA) supplement on insulin resistance (IR) and Fetuin-A and serum sirtuin1 (SIRT1) in type 2 diabetics.
Methods: In this double-blind, randomized clinical trial, 44 diabetic patients were selected. Patients were assigned to
the intervention group (22 subjects) and placebo (22 subjects) and received a capsule containing 180 mg of EA per
day or placebo for eight weeks, respectively. At the beginning and end of the study, anthropometric indices, fasting
plasma glucose (FPG), plasma insulin level, IR, Fetuin-A, and SIRT1 were measured. Statistical analysis was performed
using SPSS software.
Results: At the beginning and end of the study, there was no signifcant diference between the two groups regarding anthropometric indices (P>0.05). At the end of the survey, EA supplementation signifcantly reduced FPG, insulin,
IR, and Fetuin-A and increased SIRT1 levels compared with the placebo group (P<0.05). However, these changes were
not signifcant in the placebo group (P>0.05).
Conclusion: EA with antioxidant properties plays an essential role in reducing the macrovascular and microvascular
complications of diabetes by reducing infammation and insulin resistanc
Effect of exercise in water on the musculoskeletal pain in pregnant women: a randomized controlled trial
Background: Musculoskeletal disorders have been a major cause of disability in pregnant women. The aim of this study is to determine the effect of exercise in an aquatic environment on the musculoskeletal pain among pregnant women. Material and methods: This randomized clinical trial was conducted on 54 pregnant women aged 20-35 years. The subjects were divided into the intervention group and control groups. Women who were in 20 to 26 weeks of gestation were included in the study. The intervention was Water Exercise in Pregnancy program conducted from week 20 to week 34. The control group received standard prenatal care. Musculoskeletal complications were assessed using the Nordic questionnaires at the baseline and, 4th and 8th week of pregnancy. The intensity of pain was assessed using a visual analog scale in the two groups. Data were analyzed using descriptive and inferential statistics via the SPSS v.16. The lsmeans package was used to examine comparisons. Results: Results of the study showed that level of discomfort and musculoskeletal complications in the intervention group was significantly reduced during the 4th and 8th week of the study compared to the control group (p<0.001). After the intervention, intensity of musculoskeletal pain in the intervention group showed a significant decrease compared to the control group (p<0.001). Conclusion: Exercise in water during pregnancy can be effective to reduce musculoskeletal complications. Aquatic exercises should be developed in the exercise program for pregnant women with musculoskeletal pain. © 2021 World Scientific Publishing Company.
Author keywords
Musculoskeletal pain; Pregnancy; Water exercis