Qazvin University of Medical Sciences

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    10283 research outputs found

    Effect of an Eight-week High-intensity Interval Training Program on Serum Cardiac Troponin I Level of Streptozotocin-induced Diabetic Rats

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    Background One of the complications of diabetes, as a chronic metabolic disorder, is cardiovascular diseases. Objective This study aims to investigate the effect of an eight-week High-Intensity Interval Training (HIIT) program on serum Cardiac troponin I (CtnI) level in streptozotocin-induced diabetic rats. Methods In this experimental clinical trial, 30 rats were randomly assigned into three groups of healthy Control (C), Diabetic (D), and diabetic+training (D+T). The third group performed the training which included a treadmill running at an intensity of 85%-90% of maximum speed in 6-12 sessions of 2 min for 8 weeks, 5 days per week. Blood glucose level and high-sensitive CtnI levels were measured 48 hours after the last training session and 12 hours of fasting. One-way ANOVA and Tukey’s test were used to analyze the collected data, considering a significance level of P<0.05. Findings The induction of diabetes caused a significant increase in blood glucose (P=0.01) and high-sensitive CtnI (P=0.01) levels in the D group. Also, a significant difference was observed in the blood glucose level of D+T group compared to the D group (P=0.001). The CtnI level also slightly reduced (11%) in the D+T group compared to the D group, but it was not statistically significant (P=0.591). Conclusion he HIIT program can reduce the fasting blood glucose and increase the serum level of highsensitive CtnI to some extent in diabetic rats; therefore, it can be an appropriate strategy for diabetics. However, there is a need for more studies in this area

    Assessing the General Health Indicators Predicting Marital Satisfaction in Older Couples

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    Background Due to the increasing life expectancy and aging population, attention to general health and marital satisfaction of older people can provide an opportunity to improve their living conditions. Objective This study aims to assess the general health indicators of older couples to predict their marital satisfaction. Methods This descriptive cross-sectional study was conducted on 110 older couples (men and women) living in Qazvin, Iran who were selected using two-stage cluster sampling technique. A demographic form, General Health Questionnaire (GHQ) and The ENRICH Marital Satisfaction Scale (EMSS) were used to collect data. Descriptive statistics and multivariate regression analysis were used for data analysis. Findings The Mean±SD age of older women and Men±SD was 64.15±5.46 years and 67.68±6.93 years, respectively. Their Mean±SD EMSS score was reported 109.72±12.58. Multivariate analysis showed that gender (β=0.169, P=0.050), age (β=0.097, P=0.567), age of marriage (β=0.214, P=0.002), somatic symptoms (β=0.233, P=0.013), anxiety/insomnia (β=0.227, P=0.008), social dysfunction (β=0.326, P<0.001), and depression (β=0.356, P<0.001) could significantly predict marital satisfaction. Conclusion Different dimensions of general health can affect marital satisfaction of older couples. Therefore, interventions in these domains and the promotion of general health level can lead to increased marital satisfaction and, consequently, quality of life in the elderly

    Association of White Blood Cell Count With Metabolic Syndrome in Obese Men and Women

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    Background Despite the widespread obesity epidemic in the world, not all obese people are equally susceptible to the complications of obesity. Inflammatory factors play an important role in the complications of obesity. Objective This study aims to evaluate the association of White Blood Cell (WBC) count with metabolic syndrome in overweight/obese men and women. Methods This cross-sectional study is a part of the Qazvin Metabolic Disease Study (QMDS) conducted in 2010 in Qazvin, Iran. Participants were 622 obese people with a body mass index (BMI) ≥25 kg/m2, recruited from the QMDS. Metabolic syndrome was defined according to the Adult Treatment Panel III criteria. Data were analyzed using Chi-square test, t-test, and logistic regression analysis (to evaluate the relationship between WBC count quartiles and metabolic syndrome). Findings Prevalence of metabolic syndrome was not significantly different between men and women. In men, prevalence of metabolic syndrome and its components were not different between WBC quartiles. In women, 32.2% and 60.5% had metabolic syndrome in the first and fourth quartiles of WBC count, respectively (P<0.001). Moreover, the prevalence of insulin resistance was higher in fourth quartile compared to the first quartile (47.7% vs. 25.6%, P<0.001). After controlling the effects of age and BMI factors, the risk of metabolic syndrome in the fourth quartile of WBC count remained significant in women (OR=2.56, P<0.01). Conclusion Association of WBC count with metabolic syndrome is significant in obese women compared to obese men

    Decreased insulin resistance in diabetic patients by influencing Sirtuin1 and Fetuin-A following supplementation with ellagic acid: a randomized controlled trial

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    Background: The benefcial efects of polyphenols have been reported. This study aimed to investigate the efect of oral Ellagic acid (EA) supplement on insulin resistance (IR) and Fetuin-A and serum sirtuin1 (SIRT1) in type 2 diabetics. Methods: In this double-blind, randomized clinical trial, 44 diabetic patients were selected. Patients were assigned to the intervention group (22 subjects) and placebo (22 subjects) and received a capsule containing 180 mg of EA per day or placebo for eight weeks, respectively. At the beginning and end of the study, anthropometric indices, fasting plasma glucose (FPG), plasma insulin level, IR, Fetuin-A, and SIRT1 were measured. Statistical analysis was performed using SPSS software. Results: At the beginning and end of the study, there was no signifcant diference between the two groups regarding anthropometric indices (P>0.05). At the end of the survey, EA supplementation signifcantly reduced FPG, insulin, IR, and Fetuin-A and increased SIRT1 levels compared with the placebo group (P<0.05). However, these changes were not signifcant in the placebo group (P>0.05). Conclusion: EA with antioxidant properties plays an essential role in reducing the macrovascular and microvascular complications of diabetes by reducing infammation and insulin resistanc

    Effect of exercise in water on the musculoskeletal pain in pregnant women: a randomized controlled trial

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    Background: Musculoskeletal disorders have been a major cause of disability in pregnant women. The aim of this study is to determine the effect of exercise in an aquatic environment on the musculoskeletal pain among pregnant women. Material and methods: This randomized clinical trial was conducted on 54 pregnant women aged 20-35 years. The subjects were divided into the intervention group and control groups. Women who were in 20 to 26 weeks of gestation were included in the study. The intervention was Water Exercise in Pregnancy program conducted from week 20 to week 34. The control group received standard prenatal care. Musculoskeletal complications were assessed using the Nordic questionnaires at the baseline and, 4th and 8th week of pregnancy. The intensity of pain was assessed using a visual analog scale in the two groups. Data were analyzed using descriptive and inferential statistics via the SPSS v.16. The lsmeans package was used to examine comparisons. Results: Results of the study showed that level of discomfort and musculoskeletal complications in the intervention group was significantly reduced during the 4th and 8th week of the study compared to the control group (p<0.001). After the intervention, intensity of musculoskeletal pain in the intervention group showed a significant decrease compared to the control group (p<0.001). Conclusion: Exercise in water during pregnancy can be effective to reduce musculoskeletal complications. Aquatic exercises should be developed in the exercise program for pregnant women with musculoskeletal pain. © 2021 World Scientific Publishing Company. Author keywords Musculoskeletal pain; Pregnancy; Water exercis

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