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Association between hypertension and insulin resistance in non-diabetic adult populations: A community-based study from the Iran
Get PDFBackground and objectives: High blood pressure increases the probability of insulin resistance and hyperinsulinemia.
Also, insulin resistance can be defined as a risk factor for hypertension. The present study investigated the
relationship between hypertension and insulin resistance in non-diabetic participants who were referred to Qazvin
Metabolic Diseases Center.
Material and methods: In this cross sectional study, 1103 participants (111 non-diabetic with newly diagnosed
hypertension and 992 normotensive subjects aged ≥ 20 years) were enrolled from September 2014 to April 2016
in Qazvin (Iran). Systolic and diastolic blood pressure, insulin resistance, waist circumference, body mass index,
triglycerides, cholesterol, LDL-cholesterol, fasting blood glucose (FBG) were measured. Fasting triglyceride to highdensity
lipoprotein cholesterol ratio (TG/HDL-C) was used as a surrogate of insulin resistance. Data were analyzed
using SPSS software and p < 0.05 was assumed as significant level.
Results: Ten percent of all participants had hypertension. TG/HDL-C was 3.78 ± 3.28 in non-HTN and 5.76 ± 5.35
in HTN participants (p < 0.001). The frequency of all cardio-metabolic risk factors (except HDL cholesterol level)
was higher in hypertensive group, after adjusting for age and gender (p < 0.001).
Conclusion: Based on these results, essential hypertension is associated with a higher prevalence of hyperinsulinemia
and insulin resistance in the non-diabetic community in Iran
بررسی تاثیر پرستاری از راه دور ( تله نرسینگ) بر کیفیت زندگی مراقبین بیماران سالمند مبتلا به سکته مغزی
Get PDFتصفیه فاضلاب صنعت چاپ و بسته بندی با استفاده از فرآیند انعقاد الکتریکی- شناورسازی: اثربخشی همزمان پارامترهای مهم و اقتصادی_چکیده طرح تحقیقاتی)
Get PDFبررسی تاثیر پوشش خوراکی حاوی باکتریهای پروبیوتیک بر ویژگیهای کیفی و پایداری نگهداری گوشت سینه مرغ عملآوری شده پخته در طی نگهداری به صورت سرد (Cº4)(فایل دفاع نهایی)
Get PDFPrevention of lung complications following paraquat poisoning by silymarin, n-acetyl cysteine and hydrocortisone: An experimental study
Get PDFBackground: Paraquat poisoning results in multi-organ failure, primarily pulmonary fibrosis,
acute renal failure, and hepatic impairment. The present study was designed to evaluate three
treatment regimens, such as N-Acetyl cysteine (NAC), silymarin and hydrocortisone in the
prevention of lung fibrosis after ingestion of toxic doses of paraquat in rats.
Methods: Male Sprague-Dawley rats (N=20) were randomly divided into four groups of five
each. The drugs and paraquat were given to the rats orally. All rat groups received one oral
dose of paraquat (10 mg/kg) once daily for 1 week. The first group received a daily oral dose
of silymarin (600 mg/kg) for 2 weeks. The second group received a daily oral dose of NAC
(500 mg/kg) for 2 weeks. The third group was given daily oral doses of NAC (500 mg/kg)
and hydrocortisone (50 mg/kg) for 2 weeks. The fourth group (controls) received no drugs
other than paraquat. The experiment continued for 4 weeks. After the experiment, autopsy was
performed on all rats and the lungs were examined histopathologically.
Results: The results of histopathology examinations for peribronchial inflammation in the
groups were shown that NAC plus hydrocortisone and silymarin had notable effects in the
prevention of lung inflammation. Septal widening in the lungs was also observed in group
three less than that in the other groups.
Conclusion: Based on the results, silymarin, NAC and hydrocortisone may be used as
a palliative treatment in paraquat poisoning specifically aimed at preventing the acute and
chronic lung injuries as the worst complication of the poisoning
In Vitro Bacterial Leakage at the Implant-Abutment Connection of Two Dental Implant Systems with Internal Connection
Get PDFAssociation of serum level of 25-hydroxy vitamin D with Oral Lichen Planus. A case-control study.
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