Hochschule Bonn-Rhein-Sieg
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Was tun gegen Infektionsjournalismus? Die mediale Allgegenwart des Virus und die vergessenen Themen
No full textDocker and Kubernetes at the university: Using container technology for science and teaching
No full textThis paper gives an overview of how we can benefit from using container technology in our academic work. It aims to be a starting point for fellow researchers which also think about applying these technologies. Hence, we focus on decribing our own experiences and motivations instead of proving hard scientific facts
3-Hydroxyisobutyrate Dehydrogenase (HIBADH) deficiency - a novel disorder of valine metabolism
Get PDF3-Hydroxyisobutyric acid (3HiB) is an intermediate in the degradation of the branched-chain amino acid valine. Disorders in valine degradation can lead to 3HiB accumulation and its excretion in the urine. This article describes the first two patients with a new metabolic disorder, 3-hydroxyisobutyrate dehydrogenase (HIBADH) deficiency, its phenotype and its treatment with a low-valine diet. The detected mutation in the HIBADH gene leads to nonsense-mediated mRNA decay of the mutant allele and to a complete loss-of-function of the enzyme. Under strict adherence to a low-valine diet a rapid decrease of 3HiB excretion in the urine was observed. Due to limited patient numbers and intrafamilial differences in phenotype with one affected and one unaffected individual, the clinical phenotype of HIBADH deficiency needs further evaluation
‚Making Media‘: Zum Kreativitätsdispositiv zwischen Medienästhetik, Kommunikationsvermittlung und Designdidaktik
No full textZwei etablierte Ansätze innerhalb der Gestaltungs- und Medienpraxis, die Methode des ‚Design Thinking‘ sowie des ‚Serious Play‘, sind für den medienpädagogischen Einsatz sowohl zu transformieren als auch zu komplettieren. Dazu werden konkrete Spielzeuge privilegiert, um diese als Mittel zur Vermittlung medial-gestalterischer Kreativitätspraktiken innerhalb der Medienpädagogik erneut zu etablieren und virtuell nutzbar zu machen. Dabei geht es insbesondere um die Konzeption, Ästhetik und soziale Funktion des Interfaces innerhalb eines genuin technologischen Rahmens.Two established approaches within design and media practice, the method of ‘ Design Thinking’ as well as the method of ‘Serious Play’, are to be both transformed and completed for media pedagogical use. To this end, concrete toys are privileged in order to re-establish them as a means of conveying media-design creativity practices within media education and to make them virtually usable. In particular, this involves the conception, aesthetics and social function of the interface within a genuinely techno-logical framework
The Value of Consistency: Portfolio Labeling Strategies and Impact on Winery Brand Equity
No full textThe reported research examines the impact of product portfolio labeling strategies on brand reputation and equity. A netnographic approach allowed to observe winery portfolio labeling approaches and create a typology of winery labeling strategies. Expert evaluation served to assess the dependent variable brand equity by deploying a regression analysis. For the observed wine industry, being part of the food industry, creating consistent and recognizable brands has a direct relevance for reducing (sustainability-related) food information overload and thereby building sustainable brand equity. The results uncover the relative importance of each of the six identified labeling strategies as well as their impact on reputation and brand equity creation. The results point to the need to establish a consistent, strategically founded product communication. Such an approach, with a positive effect on reputation building can serve to build sustainable brand equity. “Stuck in the middle”-type strategies apparently diminish winery brand equity exploitation. The findings contribute to the knowledge on food labels in product communication strategies and their impact on organizational brand equity, thereby having high relevance for the implementation of environmental certification initiatives in an organizational context. The article deploys a novel research approach in an under-researched area to provide new insights for further research as well as implications for practice
