Jurnal Kedokteran Universitas Lampung
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CRITICAL LIMB ISCHEMIA IN 27 YEARS OLD HIV PATIENT: A CASE REPORT
Full text linkThe prevalence of peripheral arterial disease (PAD) is high in the HIV-infected population and is much higher than expected in the general population. A 27 years old male patient came to Cipto Mangunkusumo General Hospital (RSCM) with chief complaint of pain on right leg which worsened since 2 days prior admission. Patient was diagnosed HIV positive 8 months prior admission and had already on ARV treatment Duviral (AZT/3TC) and Alluvia (lopinavir/ritonavir) since then. CT angiography showed stenosis of femoral communis artery with total stenosis of right posterior tibialis artery. Patient was diagnosed with criticl limb ischemia and got amputation. Some theories of PAD mechanism in HIV patient have been proposed. Highly ac tive antiretroviral therapy (HAART) has decreased the mortality and illnesses related to HIV infection. However, a variety of atherogenic metabolic abnormalities, including dyslipidemia, lipodystrophy, and also thickened intima-media thickness have been observed after the introduction of HAART, especially using Protease Inhibitors. Human Imunodeficiency Virus itself is also thought to have role in injury to the arterial wall such as via chemokine CCL2/MCP-1, a critical mediator of atherosclerosis. All HIV-infected patients candidate to antiretroviral therapy and patients already under treatment should undergo an assessment that includes the evaluation of the cardiovascular risk. [JuKe Unila 2014; 4(8):218-224
EBOLA HEMORRHAGIC FEVER: CLINICAL MANAGEMENT AND PREVENTION
Full text linkEbola hemorrhagic fever is one of at least 30 known viruses capable of causing viral hemorrhagic fever syndrome. It is a severe, often fatal disease in humans and nonhuman primates (such as monkeys, gorillas, and chimpanzees). Ebola first appeared in 1976 in 2 simultaneous outbreaks, in Nzara, Sudan, and in Yambuku, Democratic Republic of Congo. The latter was in a village situated near the Ebola River, from which the disease takes its name. The current (2014) Ebola virus outbreak in West Africa has seized the world's attention, because this become the deadliest Ebola outbreak in recorded history and it is significant and primarily involves 4 African countries—Guinea, Liberia, Sierra Leone, and Nigeria. Besides the high mortality rate, the cure for Ebola disease has not been found yet. As of Augustus 31, 2014, 3.707 total suspected or confirmed cases (2.106 laboratory-confirmed) had been reported in these countries, resulting in 1.848 deaths. Based on genetic analysis, the virus is 97% identical to the Zaire ebolavirus identified in recent (earlier in 2014) cases in Gabon and the Democratic Republic of the Congo. Ebola disease management generally in the form of therapeutic support, relieve symptoms, and focus on the early identification of complications. Prognosis is poor, especially Ebolavirus Zaire strain, which has a case fatality rate of up to 89%. [JuKe Unila 2014; 4(8):245-253
The Relation Ship Learning Styles And Student's Achievement Of Lampung University Faculty Of Medicine
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Relations Aspects of Personal Hygiene And Behavior Aspects with Worm Eggs Nail Contamination Risk At 4th , 5th And 6th Grade of State Elementary School 2 Raja Basa Districts Bandar Lampung Academic Year 2012/2013
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THE BENEFIT AND WEAKNESS OF ORAL EXAMINATION IN MEDICAL EDUCATION
Full text linkOral examination was abandoned because a lot of low validity and reliability by many countries around the world who are applying these methods to assess student competency. In Indonesia, there are still many faculty who apply this method in both the stage assessment undergraduate and clinical rotation phase. In this article, we will discuss the existence of an oral examination in medical education. More emphasize at the validity and reliability of oral examination so that it can be accepted as a method that is believed to assess the ability of students in medical education. Experts of medical education have conducted a study by modifying the traditional oral examination to be more valid and realeabel, example: structured oral examination. Oral examination can still be used as a method of the assessment in medical education and it’s depends on the policy of institution [JuKe Unila 2014; 4(8):233-239
HUMAN LEUKOCYTE ANTIGEN (HLA) GENE IN DENGUE INFECTION
Full text linkThe geographic distribution of the Dengue Virus (DENV) and the incidence of the viral infection have grown fast in recent decades, and dengue fever is considered to be one of the most important reemergent tropical diseases. The majority of dengue infections are subclinical; however, the clinical manifestations of dengue infection range from the benign, self-limited Dengue Fever (DF) to a vasculopathy syndrome known as Dengue Hemorrhagic Fever (DHF) that can lead to hypovolemic Dengue Shock Syndrome (DSS). Several epidemiological studies indicated that genetic factors constitute important components in disease susceptibility. Several human HLA class I and II alleles are associated with development of DHF. The human leukocyte antigen alleles have been implicated as probable genetic markers in predicting the susceptibility and/-or protection to severe manifestations of DENV infection. [JuKe Unila 2014; 4(8):240-244