Journal of Agromedicine and Medical Sciences
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Risk Factor Analysis of Residential Topography and Age on Prostate Cancer Incidence
No full textProstate cancer is malignancy that originates from the luminal and basal epithelial acinar of prostate gland. Global Cancer Statistics in 2020 stated that prostate cancer is the third most common type of cancer in the world. The incidence and mortality of prostate cancer in Indonesia ranks 10th out of 32 Asian countries. Prostate cancer is multifactorial disease influenced by genetic mutations and inflammation. Research shows risk factors include increasing age and topographical factors of residence. Literature studies from various sources related to age and topography of residence in prostate cancer are still very limited. This study aims to analyze the effect of topographic profile factors of rice fields around the residence and age on the severity of prostate cancer An Observational analytic study was conducted with a case control design. Total of 177 samples using total sampling method. Age variable parameters are less than or more than 65 years. While the topography of residence uses a cut-off point of 39%. The results of the chi-square test found a significant influence between topographic profile of rice fields around the residence with prostate cancer incidence (p = 0.028, OR = 2.155). The results also found a significant influence between age factor with prostate cancer incidence (p=0.018, OR=2.187). The incidence of prostate cancer caused by the topographic profile of residence and age amounted to 7.2%. In conclusion shows that the topographic profile of the rice field area around the residence and age have a significant influence on prostate cancer severity.
Keywords: age, pollutant, prostate cancer, residence, rice fiel
Prediction of Coronary Heart Disease on Civil Servants in Jember by Framingham Risk Score
Full text linkCoronary heart disease is one of the biggest causes of death in developing countries. Civil servants (PNS) are a group of people who are susceptible to the disease because of their busy lives. Framingham risk score (FRS) can predict the occurrence of coronary heart disease in the next 10 years. The purpose of this study was to determine the prediction of coronary heart disease for the next 10 years in civil servants in Jember Regency. This type of research is descriptive observational with a cross sectional design. The data was taken from the medical records of patients with echelon II and III civil servants who did a medical sheck up at Dr. Soebandi Hospital in December 2013. Prediction of coronary heart disease for the next 10 years using the FRS method. From 63 medical record data, the prediction results of coronary heart disease in civil servants were 76.2% low risk, 17.5% moderate risk, and 6.3% high risk.
Keywords: coronary heart disease, civil servants, framingham risk scor
Correlation Analysis of Stress and Blood Pressure in Hypertensive Farm Laborers in the Mumbulsari Jember Health Center Working Area
Full text linkHypertension has a high prevalence of patients in the world, as well as in Mumbulsari Jember District. This is due to many risk factors for the incidence of hypertension and doesn’t cause significant symptoms. Psychological stress is one of the factors causing hypertension. Work, economic, and social problems are triggers for stress. This is experienced by farm laborers with complex problems that cause psychological stress conditions. The purpose of this study was to determine whether there is a correlation between stress and increased blood pressure in hypertensive farm laborers in the Mumbulsari Jember Health Center Working Area. This research is an analytic observational research with cross sectional study design. The sampling method was convenience sampling. The data used were primary data (Self Reporting Questionnaire 20 (SRQ-20)) and secondary data (medical records of patients in Puskesmas Mumbulsari Jember). The results of this study showed normal psychology, namely in 11 respondents (42.3%) experiencing stage 1 hypertension conditions and 15 respondents (57.7%) experiencing stage 2 hypertension. SRQ-20 results identified mental distress, namely 23 respondents (60.5%) experienced stage 1 hypertension and 15 respondents (39.5%) experienced stage 2 hypertension. The results of the analysis showed there was no significant correlation between stress and increased blood pressure in hypertensive farm laborers in the working area of the Mumbulsari Jember Health Center with a Ï-value of 0.151 (Ï>0.05). This study concluded that there is no correlation between stress and increased blood pressure in hypertensive farm laborers in the Mumbulsari Jember Health Center Working Area.
Keywords: Hypertension, Stress, SRQ-20, Farm Labore
Anti-Inflammatory Activity of Stem Barks Ethanol Extracts of Asam Kandis On Male White Rats
No full textInflammation is a complex series of changes in tissue due to tissue injury caused by bacteria, trauma, chemicals, heat, and pain. Gamboge (Garcinia xanthochymus) is a fruit-bearing tree native to Southeast Asia. Plants of the genus garcinia are rich in secondary metabolites such as flavonoids, steroids, and triterpenes which have potential pharmacological activity. This study aimed to determine the anti-inflammatory activity based on the reduction in edema volume of Gamboge (Garcinia xanthochymus) stem bark. The inquiry was experimental. Through maceration, an ethanol extract of the gamboge stem was created. The animals were divided into five groups, each containing five white male rats. The test given was a suspension of gamboge ethanol extract at doses of 200, 400, and 600 mg/kgBW, a negative control of 1% Na CMC suspension, and a positive control of 2.25 mg/kgBW sodium diclofenac. Observations were made for 6 hours, and then data were analyzed using a two-way analysis of variance (ANOVA) test. The results showed that gamboge ethanolic extract was proven to have an anti-inflammatory effect in white male rats induced by carrageenan starting at doses of 200, 400, and 600 mg/kgBW, marked by a significant difference to the negative control (p<0.05). The 600mg/kgBW dose group showed no significantly different results from the positive control group (p>.05). These results concluded that the dose group 600mg/kgBW was the best dose of gamboge stem ethanol extract had an anti-inflammatory activity based on reducing the volume of leg edema of white male rats.
Keywords: Asam Kandis Stem Bark; Anti-Inflammation; Male White Rat
Analysis of Health Literacy Index Difference Amongst Generation in Jagapura Primary Healthcare Work Area
Full text linkHealth literacy is one of the factors which has a big contribution to a person's health status. The rapidity of technology growth eases access to health information, this situation has to be balanced with good health literacy index. Several factors as generation, occupation, and education influence health literacy index. Many measuring tools have been developed to assess the health literacy index. Researcher uses the latest health literacy survey questionnaire in Indonesia, namely HLS-EU-SQ10-IDN which contains 10 questions. This type of research is analytic observational. The research was conducted in the work area of ​​the Jagapura Primary Health Care, Gegesik District, Cirebon Regency, West Java. A total of 146 people that spread over five village is taken as samples with purposive sampling method. The results of Chi Square analysis is the association between generation and health literacy index showed insignificant results with p = 0.705. For the correlation with work, the results are also insignificant with p = 0.296. Meanwhile, education level is associated significantly with p = 0.018. The data obtained indicate that there is no significant correlation between generational differences and the health literacy index. Older generation with higher educational background tends to have better health literacy index. On the other hand, the researcher concludes that government need a strategy to increase the quantity and quality of education in Indonesia as an endeavour to increase health literacy index in our society.
Keywords: health literacy index, generation, education, occupatio
Pericardial Effusion as A Clue to The Diagnosis of Systemic Lupus Erythematosus: A Case Report
Full text linkPericardial effusion (PE) is accumulation of fluid in the pericardial sac. There are broad etiologies of PE, such as inflammation, infection, and malignancy. The etiology must be discovered because the treatment will be focused based on the cause. We present a 40-year-old female who came to the cardiology clinic with exertional dyspnea as the only symptom. The patient had a history of unspecific joint pain two months prior. Physical examination, chest x-ray, and electrocardiography revealed no specific findings. However, on echocardiography, we found moderate circumferential pericardial effusion. The patient then admitted for further evaluation. Blood counts, peripheral blood smear, urinalysis, and immunoserology examination such as ANA and anti-dsDNA was ordered and the result led to the diagnosis of systemic lupus erythematosus (SLE). High dose steroid injection was given for five days and the symptoms disappeared. Follow-up echocardiography after a week of hospital admission revealed significant reduction of pericardial fluid
Determination Of Total Flavonoid Content Of Yellow Wood (Arcangelisia Flava (L.) Merr) Extract And Antibacterial Activity Against Staphylococcus aureus
No full textYellow wood (Arcangelisia flava) is a medicinal plant that has received little attention. Merr and (L.). Yellow wood has antibacterial, antioxidant, anti-hyperlipidemic, and anti-cancer properties. Furthermore, yellow wood is known to contain a range of flavonoid compounds, such as hydroxylarcangelicin, which has broad antibacterial activity. The purpose of this research is to investigate the total flavonoid content of yellowwood extract as well as its antibacterial activity against Staphylococcus aureus bacteria. The manufacturing of methanol extract, characterization of simplisia, phytochemical screening, and determination of the total flavonoid levels of the yellow wood methanol extract by a visible spectroscopic approach were all part of this stage of research. Next, use chloramphenicol as a positive control and dimethyl sulfoxide (DMSO) as a negative control to test antibacterial activity against Staphylococcus aureus. The results of this study can be concluded to show that the total flavonoid levels in the methanol extract of yellow wood at a metanol concentration of 80% were 228,314 ± 5,4171 mg QE/g. At a 90% concentration of 245.993 ± 6.7626 mg QE/g and a 100% concentration of 265.953 3.0853 mg QE/g.
Keywords: Yellow wood; Flavonoids; Spektrofotometri Visible; Stphylococcus aureus
The Relationship Between Proteinuria Degree of Pre-eclampsia Mother and Incidence of Neonatal Low Birth Weight at General Hospital Karsa Husada Batu
No full textPreeclampsia is hypertension that occurs after 20 weeks of gestation with proteinuria. As one of the second highest causes of maternal death in Indonesia, preeclampsia must be detected and managed quickly and appropriately before complications that threaten the mother and fetus arise. One of the conditions that can be associated with preeclampsia is the outcome of low birth weight babies (LBW). This study aimed to determine the relationship between the degree of proteinuria in preeclampsia mothers and incidence of LBW at RSU Karsa Husada Batu. This study used a cross-sectional study design. Data was collected from medical record. The independent variable in this study was the degree of proteinuria and the dependent variable was diagnosis of LBW. The population in this study were all preeclampsia mothers and their babies from preeclampsia patients at RSU Karsa Husada Batu in 2021 with total of 38 patient. Sampling was done by total population sampling. Data analysis used in the study is chi square test. The results of this study showed that there is a relationship between the degree of proteinuria in preeclampsia mothers and incidence of LBW or the higher the degree of proteinuria, the higher the risk of babies from preeclampsia patients experiencing LBW ( p=0,005 ; CI = 95%).
Keywords: Preeclampsia, Proteinuria, LB
Effect of Massage with Olive Oil and Scrub on Xerosis et Morbus Hansen Multi Basiler: (Case Report at Leprosy Rehabilitation Unit Donorejo Jepara)
Full text linkMorbus Hansen or leprosy is a chronic granulomatous infection caused by Mycobacterium leprae. This disease attacks the peripheral nerves and other organs or systems in the body. M. leprae attacks the stratum corneum so that it makes the skin rough, scaly and cracked or what is called xerosis. The appearance of xerosis is due to mechanisms that contribute to decreased hydration of the stratum corneum and defects in sweat gland function. Prevention of damage to the integrity of the skin (xerosis) in leprosy patients can use olive oil, vaseline, coconut oil, and olive oil. This case report was conducted to determine the effect of massage with olive oil and scrub in overcoming skin problems in leprosy subjects. Providing a physiotherapy program at the Donorejo Leprosy Rehabilitation Unit in Jepara, using physiotherapy modalities in the form of massage with olive oil and scrubs. After therapy was carried out on the subject by giving massage with olive oil and scrub, there was a significant decrease in the ODSS scale value from an initial value of two to a value of one. The results showed that massage with olive oil and scrub was effective in improving the skin of leprosy patients which could be used as an alternative intervention in skin care for leprosy sufferers to prevent further defects