Jurnal Gizi Klinik Indonesia
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Efek ekstrak teh hijau (Camellia sinensis (L.) O. Kuntze var. assamica) terhadap berat badan dan kadar malondialdehid wanita overweight
Get PDFBackground: Overweight and obesity were risk factors of various degenerative diseases. Green tea extract contains polyphenol compounds, particularly catechins which act as antioxidants, fat dissolvent and aid lipolysis. Thus, it is necessary to study the use of green tea as an alternative treatment to overcome overweight.Objective: To identify the effect of green tea extract supplementation on body weight and malondialdehide (MDA) level of overweight women in Yogyakarta District Health Office.Method: This was an experimental study with double-blind randomized controlled trial design. Subject of the study were divided into two groups; one group consumed green tea extract capsules and the other consumed placebo. Weight, 6 times 24 hours recall, and level of MDA were measured on every subject.Results: The results revealed that green tea extract has a weight-reducing effect and decrease MDA level of overweight women, though the reduction of weight and MDA level was not significant (p>0,05). Weight loss of 1.3% was observed in the treatment group, whereas the control group has an increase of 0.6% body weight, but the weight change was not significant (p=0.501, p=0.620). Changes in body weight after 12 weeks of treatment showed a significant disparity between the two groups (p=0.000). MDA level decreased by 10% in the treatment group compared to 8.3% in the control group. MDA levels pre and post intervention was significantly different in the treatment group (p=0.006), whereas in the control group there was no significant discrepancy observed (p=0.123). However, changes in MDA levels after 12 weeks of treatment showed no significant differences among groups (p=0.278). The mean nutrient intakes of subjects were still below the recommended dietary allowance (RDA), except for protein.Conclusion: Green tea extract had a weight-reducing effect and decrease MDA level of overweight women in Yogyakarta District Health Office, though the reduction was not statistically significant
Potensi minuman bubuk kedelai (var. Galunggung) sebagai minuman fungsional: sifat fisikokimia, efek hipoglikemik dan hipokolesterolemik serta status antioksidan
Get PDFBackground: Powdered soy beverage is one of the functional drink products that grow rapidly in Indonesia. The beverage comes with variety of health claims including lower blood glucose level and improve antioxidant status. Galunggung is one of Indonesian superior soybean varieties that have several advantages, such as leave rust resistant, productivity reached 1,5 tons/ha, can be cultivated in tidal lands, large seeds and sturdy pods.Objective: To determine the potential of powdered soybean (var. Galunggung) beverage as functional drink observed from physicochemical characteristics and effect of intake on glucose and cholesterol levels and antioxidant status of diabetic-hypercholesterolemic rats. Method: The physicochemical characteristics evaluation performed by measuring disperse-ability, nutritional quality (proximate analysis), dietary fi ber and in vitro antioxidant capacity (total phenol content and anti radical DPPH activity). Determination of powdered soybean (var. Galunggung) beverage effectiveness to decrease plasma glucose and cholesterol levels and improve antioxidant status were conducted using 18 Sprague-Dawley male rats aged 3 months with an average body weight of 150 g, divided into three groups: negative control (placebo), positive control (diabetichypercholesterolemia) and treatment (powdered soybean beverage diet) group.Result: Powdered soybean (var. Galunggung) beverage showed comparable physicochemical characteristics to commercial powdered soy beverage. This beverage also showed hypoglycaemic and hypocholesterolemic effects, and improve antioxidant status of diabetic-hypercholesterolemic rats. Plasma glucose level of diabetic-hypercholesterolemic rats decreased from 228.03 + 2.55 mg/dl to 123.33 ± 1.89 mg/dl, plasma cholesterol level reduced from 177.08 ± 4.64 mg/dl to 119.69 ± 2.95 mg/dl and plasma MDA levels declined from 12.01 + 0.41 mmol/l to 5.50 + 0.20 mmol/l after intervention with powdered soybean (var.Galunggung) beverage diet for 2 weeks.Conclusion: Powdered soybean (var. Galunggung) beverage has the potential to be developed as functional drink with several health claims, i.e. reduce glucose and cholesterol levels, and improve antioxidant status
Peningkatan aktivitas fagositosis dan produksi nitrit oksida pada makrofag peritoneum tikus Sprague Dawley yang diberi Lactobacillus plantarum Mut7 dan ekstrak serat ubi jalar
Get PDFBackground: Macrophages play an important role as part of the innate immune response in the gut and they represent one of the first lines of nonspecific defense against bacterial invasion. Previous studies indicated that probiotics and prebiotics may act as an immunomodulator agents. Nevertheless, research on the immunomodulatory effect of local materials has never been performed.Objective: To study the effects of Lactobacillus plantarum Mut7 and sweet potato fiber on the activity and Nitric Oxide (NO) production of peritoneal macrophages of Sprague Dawley rats.Method: Ninety six Sprague Dawley rats aged 8 weeks were divided into two groups; A (not infected with Salmonella typhimurium) and B (infected with S. typhimurium). Each group was divided into 4 subgroups and assigned to standard AIN-93M diet (KON), 109 CFU/ml of L. plantarum Mut7 (PRO), modified AIN-93M diet with sweet potato fiber (PRE), and both component (SIN). After 3 weeks of treatment, 6 rats of each subgroup were sacrificed and the peritoneal macrophages were isolated and analysed for its activity and NO production. The rest of the rats continued the treatments for another 2 weeks. At the end of the experiment, they were sacrificed and the peritoneal macrophage were isolated and analysed for its activity and NO production.Results: Oral administration of L. plantarum Mut7, sweet potato fiber, or both improve phagocytic activity of peritoneal macrophage which was indicated by an increase in the percentage of macrophages that phagocyte latex particles (p0.05), but after 5 weeks of treatment the production of NO was significantly increased (p<0.05).Conclusion: L. plantarum Mut7, sweet potato fiber, or both increase the non specific immune response as they could improve the activity and NO production of peritoneal macrophages
Obesitas sentral berhubungan dengan toleransi glukosa terganggu pada remaja perempuan
Get PDFBackground: Obesity in adolescents has become health problem in Indonesia. Central obesity is associated with insulin resistance.Theoretically, insulin resistance will cause impaired glucose tolerance (IGT) and could develop into type 2 diabetes.Objective: The aim of this study were to evaluate the difference in IGT prevalence between central and non central obesity and to identify the risk factors associated with IGT. Method: A cross sectional study was conducted at 3 private secondary schools in Yogyakarta and recruited 62 obese female students aged 12-18 years.The subjects were classified into central obesity (BMI/U> +2SD and waist circumference > p90) and non central obesity based on anthropometric data. Fasting glucose and 2 hours after loading were measured in all subjects. Differences in the proportion of IGT between the two groups was calculated by Chi-square test and risk factors associated with IGT were calculated by multivariate logistic regression with 95% confidence interval.Result: Of 62 subjects, 14 of them have IGT and the prevalence of IGT was significantly higher in the central obesity group compared to non central obesity group (11/31 vs 3/31, p=0.03). Central obesity was found to be the only risk factor of IGT (OR=4.6; 95%CI: 1.04 to 20.24). Twenty one of the subjects were found to have impaired fasting glucose (IFG) (34%) and one subject (1.6 %) had IFG+IGT. There were no differences in the proportion of IFG between central and non central obesity groups. Conclusion: The prevalence of IGT in female students with central obesity was higher compared to those with non central obesity. A female student with central obesity had 4.6-fold risk of having IGT compared to those with non central obesity
Asupan protein dan fosfor, rasio fosfor-protein, dan kadar fosfor darah pada pasien gagal ginjal kronis dengan hemodialisis
Get PDFBackground: Hyperphosphatemia has become one of the main causes of death in CKD patients on HD. Thus, correction and prevention of hyperphospatemia is a major component in the management of HD patients. High protein diet in HD patients may lead to increased serum phosphate level due to mineral metabolism disorder associated with decreased glomerular filtration rate. In addition, high protein intake often followed by high phosphate intake as high protein foods also contains high phosphate and may cause hyperphosphatemia. Meanwhile, reduction of protein intake to control phosphate level was associated with decreased health and nutritional status in CKD patients. Therefore, appropriate phosphate-protein ratio is essential to provide adequate protein intake and avoid hyperphosphatemia.Objective: To investigate the association between protein and phosphate intake, phosphate-protein ratio and blood phosphate level in CKD patients on routine HD.Method: The study used an analytic observational method with cross sectional design. There were 100 subjects involved in this study. Subject characteristics, protein and phosphate intake, phosphate-protein ratio and intake of phosphate binders were obtained through interview and 3 x24 hour food record. Serum phosphate level was analyzed by inorganic phosphorus quantification method. Food processor was used to analyze the intake of protein and phosphate. Bivariate and multivariate tests with 95% confidence interval were used to analyze the data.Results: Adequate protein intake was observed among 38% subjects, while 46% of them have excess phosphate intake.High phosphate-protein ratio was found in 20% subjects. Most subjects did not take phosphate binders regularly (61%) and have hyperphosphatemia (66%). The average protein intake, phosphate intake, phosphate-protein ratio, and blood phosphate level were 1.1 g/kg/d, 13.5 mg/kg/d, 12.8 mg/g, and 5.6 mg/dl, respectively. Bivariate test showed that there was a significant association between protein intake (p=0.037; RP=2.78), phosphate intake (p=0.005; RP=3.54), phosphate-protein ratio (p=0.045; RP=3.85), and blood phosphate level in CKD patients on routine HD. Multivariate analysis revealed that high phosphate intake and did not consume phosphate binders regularly were risk factors of hyperphosphatemia (p=0.000; OR=6.543; CI 95%:2.357-18.164 dan p=0.024; OR=3.413; CI 95%:1.179; R2=0.42).Conclusion: Consumtion of low phosphate foods and phosphate binders may reduce the risk of hyperphosphatemia in CKD patients on routine HD
Pengetahuan dan sikap orang tua hubungannya dengan pola konsumsi dan status gizi anak autis
Get PDFBackground: The prevalence of autistic spectrum disorder (ASD) has increased in recent years. In 1993 the prevalence of ASD was 2-4 cases per 10.000 children. The number increased significantly to 152 cases per 10.000 children in 2003 (0.15-0.2%). In addition to diet, nutritional status can be influenced by parent’s knowledge and attitudess toward children with autism. Improving parent’s knowledge and attitudess about autism can be an effective way to manage children with autism.Objective: To examine the relationship between parent’s knowledge and attitudes toward autism with dietary pattern and nutritional status of autistic children in SLBN Semarang.Methods: This was an observational study with cross sectional design. The subjects were students with autism who attended SLBN Semarang and their parents. A questionaire was used to collect the information on parent’s knowledge and attitudes toward autism, Food Frequency Questionnaire (FFQ) was used to obtain the data on gluten and casein consumption, whereas the data on nutritional status were measured by weight and height of the children. Chi square and Fisher Exact test were used to analyze the data.Result: As many as 55.3% of parents have good knowledge and 65.8% have a possitive attitudes toward autism. Fifty percent of children presented with good consumption pattern of gluten, 65% exhibited good consumption pattern of casein and 55.3% of autistic children had good consumption pattern of both gluten and casein. Almost half (47.4%) of the children were undernourished. There were no association found between parent’s knowledge and gluten and casein consumption (p>0.05); parent’s knowledge and nutritional status (p>0.05); and parent’s attitudes and nutritional status (p>0.05). Only parent’s attitudes towards autism was found to be associated with casein and gluten consumption pattern (p<0.05).Conclusion: There was a significant association between parent’s attitudes and consumption of gluten and casein in children with autism.
Derajat keparahan infeksi Soil Transmitted Helminths terhadap status gizi dan anemia pada anak sekolah dasar
Get PDFBackgound: Indonesia as a tropical country with high humidity, has good environment for worm breeding particularly Soil Transmitted Helminths (STH). The prevalence of worm infestation in Indonesia is still relatively high, about 60% of 220 million Indonesian population, 21% of them are elementary school-age children. STH intensity greatly affects the nutritional status of patients, in wich more severe infection leads to poorer nutrition condition.Objective: To identify severity of STH infection in elementary school student at the working area of Kokap I Health Center of Kulonprogo and its correlation with nutritional status and anemia.Method: The study was undertaken in 25 elementary schools at the working area of Kokap I Health Center of Kulonprogo. Samples were all students of grade I as many as 241 students. Worm examination was done by using Kato-Katz method, assessment of nutrition status was based on body weight according to height (weight/height), anemia status was assessed from Hb level using Cyanmethaemoglobin method.Results: The results of the study showed that most of students (83,6%) were well nourished and were non anemic (84,9%). No student belonged to severe anemic category, 3 students (1,3%) had anemia at medium category and 31 students (13,8%) were slightly anemic. Out of 51 students that positively got STH infection, 16 students (31.4%) had light infection of A. lumbricoides, 36 students (70,6%) had T. trichiura and 4 students (5,9%) had hookworm. A. lumbricoides infected 7 student (13,7%) and T. trichiura infected 8 student (15,7%) both at medium criteria. There was no infection at severe criteria. The result of Somers’ D analysis showed that there was no significant correlation between the two variables (p>0,05).Conclusion: There was no correlation between severity of STH infections with nutrition status and anemia in elementary school student
Faktor ibu dalam pemberian suplemen pada anak prasekolah
Get PDFBackground: Most children already meet their daily nutrient needs through food intake. However, many of them still consume food supplement. Supplement use becomes popular, but the pattern of supplement provision amongst preschool children has never been investigated. As the supplement use increases, there is an increased risk of over consumption of several micronutrients. Objective: To evaluate the predictors of preschooler’s supplement intake related to mother’s socio-demographic and lifestyle characteristics and to compare dietary pattern and nutritional status of preschool children who consume and did not consume supplements.Method: This is an observational study with case control design. The subjects were preschool children enrolled at Bandar Lampung Kindergarten and their mothers. The case and control group consisted of 79 mothers, respectively. Sociodemographic information and frequency of dietary supplement consumption were collected via parental questionnaires, including a 24-hour food recall.Result: Most children consume multivitamin supplement once a day (65.45%).The most infl uential factor for mothers to give food supplement to their child is media exposure. Mothers from families with higher income, lower educated, consume supplement and highly motivated were signifi cantly more likely to give food supplement to their child than their counterparts. Excluding nutrient intake from supplement, there were no differences in nutrient intake between supplement consumers and non-consumers. There were also no differences in nutritional status between supplement consumers and non-consumers.Conclusion: The most infl uential factor for mothers to give supplement to their child is media exposure. There were no differences in nutritional status and nutrient intake between supplement consumers and non-consumers
Pemanfaatan tepung daun kelor (Moringa oleifera Lamk) dengan pretreatment asam dan tepung ikan lele terhadap pemulihan anemia secara in vivo
Get PDFBackground: It is estimated more than 50% of the cases of anemia in the world is caused by iron (Fe) deficiency, it needs alternative sources local food that rarely used but cheap.Objective: This monofactorial experiment was done to find out whether kelor leaves powder resulted from acid pretreatment and addition of catfish powder can support the recovery of iron deficiency anemia, based on an in vivo study with iron (Fe) and hemoglobin (Hb) measurements.Methods: The experiment was a trial of anemia recovery by providing 42 wistar rats with no iron-containing feeding for 7 days, then continued for 14 days with either one of six kinds of feeding: standard feeding of AIN-93 M, kelor leaves powder or catfish powder (as control), kelor leaves powder with 0.5% citric acid pretreatment, kelor leaves powder with 0.5% citric acid pretreatment and catfish powder (1:1), kelor leaves powder with 0.5% lime pretreatment, or kelor leaves powder with 0.5% lime pretreatment and catfish powder (1:1). Criteria of anemia recovery was Fe value > 80 µg/dl and Hb > 10 g/dl. Statistical analysis was performed by using ANCOVA and LSD test.Results: The in vivo study showed that feeding rats with kelor leaves powder (respective Fe and Hb value was 101.22 µg/dl and 11.17 µg/dl), with 0.5% citric acid pretreatment (respective Fe and Hb value was 90.36 µg/dl and 10.68 µg/dl), with 0.5% lime pretreatment (respective Fe and Hb value was 115.51 µg/dl and 12.12 µg/dl), with 0.5% lime pretreatment and catfish powder (1:1) (respective Fe and Hb value was 107.29 µg/dl and 11.25 µg/dl), can be used in anemia recovery.Conclusion: The best result for anemia recovery was obtained from feeding of kelor powder leaves with 0.5% lime pretreatment
Asupan zat gizi mikro dengan fungsi kognitif pada lanjut usia
Get PDFBackground: The elderly population in Indonesia increased signifi cantly in the last two decades as the life expectancy increase from 66.7 years to 70.5 years with impact to the emergence of diseases in the elderly. One of them is degradation of cognitive function that may disrupt productivity, daily activities, and quality of life of the elderly. Adequate micronutrients intake may help in maintaining cognitive function.Objectives: To identify association between intake of micronutrients (vitamin B6, folate, vitamin C, and vitamin E) and cognitive function of the elderly at Among Yuswa Club of Banteng Baru, District of Sleman.Methods: This was an observational study with cross sectional design. Subjects were elderly people at Among Yuswa Club of Banteng Baru, District of Sleman. Data on cognitive function was obtained using the Mini Mental State Examination (MMSE) and intake of micronutrients were collected using Semi Qualitative Food Frequency Questionnaire (SQFFQ). The data was analysed by chi square and logistic regression tests.Results: The result showed statistically signifi cant association between cognitive function and intake of vitamin B6 (p=0.010; RP=2.514; 95%CI=1.133-5.575), vitamin C intake (p=0.011; RP=3.039; 95%CI=1.454-6.353) and vitamin E intake (p=0.021; RP=1.266; 95%CI=1.057-1.516); meanwhile folate intake has no signifi cant association with cognitive function (p>0.05).Conclusion: There were signifi cant associations between intake of vitamin B6, vitamin C and vitamin E with cognitive function. There was no signifi cant association found between intake of folate and cognitive function in the elderly