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    An Algebraic View of Space/Belief and Extrusion/Utterance for Concurrency/Epistemic Logic

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    International audienceWe enrich spatial constraint systems with operators to specify information and processes moving from a space to another. We shall refer to these news structures as spatial constraint systems with extrusion. We shall investigate the properties of this new family of constraint systems and illustrate their applications. From a computational point of view the new operators provide for pro-cess/information extrusion, a central concept in formalisms for mobile communication. From an epistemic point of view extrusion corresponds to a notion we shall call utterance; a piece of information that an agent communicates to others but that may be inconsistent with the agent's beliefs. Utterances can then be used to express instances of epistemic notions, which are common place in social media, such as hoaxes or intentional lies. Spatial constraint systems with extrusion can be seen as complete Heyting algebras equipped with maps to account for spatial and epistemic specification

    Small molecule-based photocrosslinkable fluorescent materials toward multilayered and high-resolution emissive patterning

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    International audiencea Solution-processable green and red-emitting fluorophores possessing photopolymerizable acrylate units have been synthesized. Photocrosslinking was successfully performed in neat thin films at room temperature under low-dose UV irradiation at 365 nm. No further curing step was necessary to achieve insoluble emissive thin films displaying high optical quality. Up to 80% of the green emitting material processed as a non-doped thin film remained after photopolymerization. Despite competitive energy transfer occurring between the excited photoinitiator and the radiative excited state of red-emitting materials, up to 40% of the initial thickness could be achieved after development. The very low RMS roughness of the green and red photocrosslinked thin films after development (RMS o 0.7 nm) allowed us to fabricate multicolored stacks again with high optical quality (RMS roughness o 1.3 nm) after two cycles of irradiation and development involving successively red and green emitters. Resolved patterns as small as 600 nm in width could be obtained upon photolithography performed under an air atmosphere. High adhesion of the photocrosslinked materials on surfaces makes the resulting emissive thin films very promising for realizing complex emissive structures on flat or bend substrates as required in multiple applications such as optical data storage, organic lasers, organic light emitting diodes or counterfeiting

    Mixed-effects model for the spatiotemporal analysis of longitudinal manifold-valued data

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    International audienceIn this work , we propose a generic hierarchical spatiotem-poral model for longitudinal manifold-valued data , which consist in repeated measurements over time for a group of individuals. This model allows us to estimate a group-average trajectory of progression , considered as a geodesic of a given Riemannian manifold. Individual trajectories of progression are obtained as random variations , which consist in parallel shifting and time reparametrization , of the average trajectory. These spatiotemporal tranformations allow us to characterize changes in the direction and in the pace at which trajectories are followed. We propose to estimate the parameters of the model using a stochastic approximation of the expectation-maximization (EM) algorithm , the Monte Carlo Markov Chain Stochastic Approximation EM (MCMC SAEM) algorithm. This generic spatiotemporal model is used to analyze the temporal progression of a family of biomarkers. This progression model estimates a normative scenario of the progressive impairments of several cognitive functions , considered here as biomarkers , during the course of Alzheimer ' s disease. The estimated average trajectory provides a normative scenario of disease progression. Random effects provide unique insights into the variations in the ordering and timing of the succession of cognitive impairments across different individuals

    Measurement of the ratio of the production cross sections times branching fractions of Bc+/- to J/psi pi+/- and B+/- to J/psi K+/- and B(Bc+/- to J/psi pi+/- pi+/- pi-/+)/B(Bc+/- to J/psi pi+/-) in pp collisions at sqrt(s) = 7 TeV

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    Submitted to JHEP, see paper for full list of authorsInternational audienceThe Bc+/- to J/psi pi+/- and Bc+/- to J/psi pi+/- pi+/- pi-/+ decay modes are studied in proton-proton collisions at a center-of-mass energy of 7 TeV with the CMS detector at the LHC. The kinematic region investigated requires Bc+/- mesons with transverse momentum pt > 15 GeV and rapidity abs(y) < 1.6. The data sample corresponds to an integrated luminosity of 5.1 inverse femtobarns. The ratio of the branching fractions B(Bc+/- to J/psi pi+/- pi+/- pi-/+)/B(Bc+/- to J/psi pi+/-) is measured to be 2.55 +/- 0.80 (stat) +/- 0.33 (syst) +0.04/-0.01 (tau[Bc+]). The ratio of the production cross sections times branching fractions (sigma(Bc+) B(Bc+ to J/psi pi+))/ (sigma(B+) B(B+ to J/psi K+)) is determined to be [0.48 +/- 0.05 (stat) +/- 0.03 (syst) +/- 0.05 (tau_{Bc})]

    Neutrino Oscillation Physics Potential of the T2K Experiment

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    40 pages, 27 figures, see paper for full list of authorsThe observation of the recent electron neutrino appearance in a muon neutrino beam and the high-precision measurement of the mixing angle θ13\theta_{13} have led to a re-evaluation of the physics potential of the T2K long-baseline neutrino oscillation experiment. Sensitivities are explored for CP violation in neutrinos, non-maximal sin22θ23\sin^22\theta_{23}, the octant of θ23\theta_{23}, and the mass hierarchy, in addition to the measurements of δCP\delta_{CP}, sin2θ23\sin^2\theta_{23}, and Δm322\Delta m^2_{32}, for various combinations of ν\nu-mode and νˉ\bar{\nu}-mode data-taking. With an exposure of 7.8×10217.8\times10^{21}~protons-on-target, T2K can achieve 1-σ\sigma resolution of 0.050(0.054) on sin2θ23\sin^2\theta_{23} and 0.040(0.045)×103 eV20.040(0.045)\times10^{-3}~\rm{eV}^2 on Δm322\Delta m^2_{32} for 100%(50%) neutrino beam mode running assuming sin2θ23=0.5\sin^2\theta_{23}=0.5 and Δm322=2.4×103\Delta m^2_{32} = 2.4\times10^{-3} eV2^2. T2K will have sensitivity to the CP-violating phase δCP\delta_{\rm{CP}} at 90% C.L. or better over a significant range. For example, if sin22θ23\sin^22\theta_{23} is maximal (i.e θ23\theta_{23}=4545^\circ) the range is 115<δCP<60-115^\circ<\delta_{\rm{CP}}<-60^\circ for normal hierarchy and +50<δCP<+130+50^\circ<\delta_{\rm{CP}}<+130^\circ for inverted hierarchy. When T2K data is combined with data from the NOν\nuA experiment, the region of oscillation parameter space where there is sensitivity to observe a non-zero δCP\delta_{CP} is substantially increased compared to if each experiment is analyzed alone

    Kinetic Analysis of a Globin-Coupled Histidine Kinase, AfGcHK: Effects of the Heme Iron Complex, Response Regulator, and Metal Cations on Autophosphorylation Activity

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    International audienceThe globin-coupled histidine kinase, AfGcHK, is a part of the two-component signal transduction system from the soil bacterium Anaeromyxobacter sp. Fw109-5. Activation of its sensor domain significantly increases its autophosphorylation activity, which targets the His183 residue of its functional domain. The phosphate group of phosphorylated AfGcHK is then transferred to the cognate response regulator. We investigated the effects of selected variables on the autophosphorylation reaction’s kinetics. The kcat values of the heme Fe(III)-OH–, Fe(III)-cyanide, Fe(III)-imidazole, and Fe(II)-O2 bound active AfGcHK forms were 1.1–1.2 min–1, and their KmATP values were 18.9–35.4 μM. However, the active form bearing a CO-bound Fe(II) heme had a kcat of 1.0 min–1 but a very high KmATP value of 357 μM, suggesting that its active site structure differs strongly from the other active forms. The Fe(II) heme-bound inactive form had kcat and KmATP values of 0.4 min–1 and 78 μM, respectively, suggesting that its low activity reflects a low affinity for ATP relative to that of the Fe(III) form. The heme-free form exhibited low activity, with kcat and KmATP values of 0.3 min–1 and 33.6 μM, respectively, suggesting that the heme iron complex is essential for high catalytic activity. Overall, our results indicate that the coordination and oxidation state of the sensor domain heme iron profoundly affect the enzyme’s catalytic activity because they modulate its ATP binding affinity and thus change its kcat/KmATP value. The effects of the response regulator and different divalent metal cations on the autophosphorylation reaction are also discusse

    Spiro-configured phenyl acridine thioxanthene dioxide as a host for efficient PhOLEDs.

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    International audienceA new high triplet organic semi-conductor based on a donor-spiro-acceptor design has been synthesised and used as a host material in high performance (EQE = 11.4%) sky blue phosphorescent organic light emitting diodes

    Analysis of Boundary-Layer Statistical Properties at Dome C, Antarctica

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    International audienceThe atmospheric boundary layer over the Antarctic Plateau is unique on account of its isolated location and extreme stability. Here we investigate the characteristics of the boundary layer using wind and temperature measurements from a 45-m high tower located at Dome C. First, spectral analysis reveals that both fields have a scaling behaviour from 30 min to 10 days (spectral slope β≈2 ). Wind and temperature time series also show a multifractal behaviour. Therefore, it is possible to fit the moment-scaling function to the universal multifractal model and obtain multifractal parameters for temperature ( α≈1.51,C1≈0.14 ) and wind speed ( α≈1.34,C1≈0.13 ). The same analysis is repeated separately in winter and summer at six different heights. The β parameter shows a strong stratification with height especially in summer, implying that properties of turbulence change surprisingly rapidly from the ground to the top of the tower

    BocopHJB 1.0.1 – User Guide

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    The original Bocop package implements a local optimization method. The optimal control problem is approximated by a finite dimensional optimization problem (NLP) using a time discretization (the direct transcription approach). The NLP problem is solved by the well known software Ipopt, using sparse exact derivatives computed by Adol-C. The second package BocopHJB implements a global optimization method. Similarly to the DynamicProgramming approach, the optimal control problem is solved in two steps. First we solve the Hamilton-Jacobi-Bellman equation satisfied by the value fonction of the problem. Then we simulate the optimal trajectory from any chosen initial condition. The computational effort is essentially taken by the first step, whose result, the value fonction, can be stored for subsequent trajectory simulations

    Centrality dependence of low-momentum direct-photon production in Au plus Au collisions at root s(NN)=200 GeV

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    International audienceThe PHENIX experiment at RHIC has measured the centrality dependence of the direct photon yield from Au+Au collisions at sNN−−−√=200 GeV down to pT=0.4 GeV/c. Photons are detected via photon conversions to e+e− pairs and an improved technique is applied that minimizes the systematic uncertainties that usually limit direct photon measurements, in particular at low pT. We find an excess of direct photons above the Ncoll-scaled yield measured in p+p collisions. This excess yield is well described by an exponential distribution with an inverse slope of about 240MeV/c in the pT range 0.6–2.0 GeV/c. While the shape of the pT distribution is independent of centrality within the experimental uncertainties, the yield increases rapidly with increasing centrality, scaling approximately with Nαpart, where α=1.38±0.03(stat)±0.07(syst)

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