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Lidar observations within the ARISE European network
International audienceA better understanding of climate change includes a better description of the variability at different altitudes, the vertical coupling between layers as well as the multi-scale interactions of the atmospheric processes. In response to these challenges numerical models including weather forecasts and operational analyses, are improved in both resolutions and vertical altitude range and new observations are expecting. Wind and temperature lidars provide useful information with an increased plus-value when they are combined with complementary information within a worldwide network. The proposed European infrastructure called the Atmospheric Dynamics Research Infrastructure in Europe (ARISE) start to deploy, in several stations (from polar to equatorial and tropical regions in the European longitude sector and adjacent regions), ground-based Lidar observations, microwave and OH radiometers and infrasound measurements in operation within the CTBT network (Comprehensive nuclear-Test-Ban Treaty). Such new data allow investigation on decadal trends, planetary waves, tides and gravity waves that can be used to validate or improve numerical models
The diagnostic accuracy of multiparametric MRI to determine pediatric brain tumor grades and types
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Search for two Higgs bosons in final states containing two photons and two bottom quarks in proton-proton collisions at 8 TeV
Submitted to Phys. Rev. D ; see paper for full list of authorsInternational audienceA search is presented for the production of two Higgs bosons in final states containing two photons and two bottom quarks. Both resonant and nonresonant hypotheses are investigated. The analyzed data correspond to an integrated luminosity of 19.7 inverse femtobarns of proton-proton collisions at sqrt(s) = 8 TeV collected with the CMS detector. Good agreement is observed between data and predictions of the standard model (SM). Upper limits are set at 95% confidence level on the production cross section of new particles and compared to the prediction for the existence of a warped extra dimension. When the decay to two Higgs bosons is kinematically allowed, assuming a mass scale LambdaR = 1 TeV for the model, the data exclude a radion scalar at masses below 980 GeV. The first Kaluza-Klein excitation mode of the graviton in Randall-Sundrum models is excluded for masses between 325 and 450 GeV. Limits set on nonresonant production constrain the parameter space for anomalous Higgs boson couplings
Measurement of the top quark mass using charged particles in collisions at sqrt(s) = 8 TeV
Submitted to Phys. Rev. D ; see paper for full list of authorsInternational audienceA novel technique for measuring the mass of the top quark that uses only the kinematic properties of its charged decay products is presented. Top quark pair events with final states with one or two charged leptons and hadronic jets are selected from the data set of 8 TeV proton-proton collisions, corresponding to an integrated luminosity of 19.7 inverse-femtobarns. By reconstructing secondary vertices inside the selected jets and computing the invariant mass of the system formed by the secondary vertex and an isolated lepton, an observable is constructed that is sensitive to the top quark mass that is expected to be robust against the energy scale of hadronic jets. The main theoretical systematic uncertainties, concerning the modeling of the fragmentation and hadronization of b quarks and the reconstruction of secondary vertices from the decays of b hadrons, are studied. A top quark mass of 173.68 +/- 0.20 (stat) +1.58 -0.97 (syst) GeV is measured. The overall systematic uncertainty is dominated by the uncertainty in the b quark fragmentation and the modeling of kinematic properties of the top quark
Proceedings of the 19th International Conference on Extending Database Technology, EDBT
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Utilisation de capteurs à réseaux de Bragg pour la mesure in-situ de déformée d'une structure alvéolaire élaborée en matériaux composite
International audienceThe use of structures made of carbon fiber-reinforced polymer (CFRP) for the design of future detectors in particle physics allows compactness and the possibility to integrate the absorber material while minimizing the dead zones. The deformations of such structures could be monitored by the use of optical fiber Bragg grating embedded directly within them. A demonstrator equipped with such sensors was made and tested on a specific set-up. The design, test results and comparison with numerical simulations are detailed in this paper
Influence of modification time and high frequency ultrasound irradiation on self-assembling of alkylphosphonic acids on stainless steel: electrochemical and spectroscopic studies
International audienceSelf-assembly of alkylphosphonic acids on stainless steel was investigated under different conditions. Four different alkylphosphonic acids exhibiting alkyl chain of various size were synthesized and studied: butylphosphonic acid (C4P), octylphosphonic acid (C8P), decylphosphonic acid (C10P), and hexadecylphosphonic acid (C16P). Electrochemistry experiments were extensively carried out in order to determine electrochemical surface blocking of adsorbed layers in function of grafting time. In term of surface blocking, an 8h modification time was optimal for all alkylphosphonic acids. Longer immersion times lead to degradation of adsorbed layers. For the first time, grafting of C16P was studied under high frequency ultrasound irradiation. Interestingly, grafting process is highly accelerated under sonication and well-covering C16P modified substrates are obtained after 1h of immersion under ultrasound irradiation. This would allow to elaborate high-quality alkylphosphonic acids modified samples within much shorter times. Water contact angles measurements and X-ray Photoelectrons Spectroscopy (XPS) confirmed presence of adsorbed alkylphosphonic acids on stainless steel surface. A very tight link between electrochemical blocking, surface hydrophobicity and species chemical grafting was established
Experimental investigation of the relation between H− negative ion density and Lyman-α emission intensity in a microwave discharge
International audienceA new mechanism for producing negative ions in low density and low power hydrogen plasmas was proposed recently. It refers to anion formation due to collisions between hydrogen atoms being in the first excited state. The proposed mechanism was indirectly supported by the quadratic relation observed between the extracted negative ion current and Lyman-α radiation of a filament-driven arc discharge, when borrowed data from the literature were combined. The present work provides experimental data comparing directly the absolute negative ion density and Lyman-α radiation in an ECR-driven hydrogen plasma source. The previously mentioned quadratic relation is not observed in the specific source studied, underlying the difficulty of distinguishing between the proposed mechanism and other negative ion production paths
Overview of the Chemistry-Aerosol Mediterranean Experiment/Aerosol Direct Radiative Forcing on the Mediterranean Climate (ChArMEx/ADRIMED) summer 2013 campaign
SSCI-VIDE+CARE:BDAInternational audienceThe Chemistry-Aerosol Mediterranean Experiment (ChArMEx; http://charmex.lsce.ipsl.fr) is a collaborative research program federating international activities to investigate Mediterranean regional chemistry-climate interactions. A special observing period (SOP-1a) including intensive airborne measurements was performed in the framework of the Aerosol Direct Radiative Impact on the regional climate in the MEDiterranean region (ADRIMED) project during the Mediterranean dry season over the western and central Mediterranean basins, with a focus on aerosol-radiation measurements and their modeling. The SOP-1a took place from 11 June to 5 July 2013. Airborne measurements were made by both the ATR-42 and F-20 French research aircraft operated from Sardinia (Italy) and instrumented for in situ and remote-sensing measurements, respectively, and by sounding and drifting balloons, launched in Minorca. The experimental setup also involved several ground-based measurement sites on islands including two ground-based reference stations in Corsica and Lampedusa and secondary monitoring sites in Minorca and Sicily. Additional measurements including lidar profiling were also performed on alert during aircraft operations at EARLINET/ACTRIS stations at Granada and Barcelona in Spain, and in southern Italy. Remote-sensing aerosol products from satellites (MSG/SEVIRI, MODIS) and from the AERONET/PHOTONS network were also used. Dedicated meso-scale and regional modeling experiments were performed in relation to this observational effort. We provide here an overview of the different surface and aircraft observations deployed during the ChArMEx/ADRIMED period and of associated modeling studies together with an analysis of the synoptic conditions that determined the aerosol emission and transport. Meteorological conditions observed during this campaign (moderate temperatures and southern flows) were not favorable to producing high levels of atmospheric pollutants or intense biomass burning events in the region. However, numerous mineral dust plumes were observed during the campaign, with the main sources located in Morocco, Algeria and Tunisia, leading to aerosol optical depth (AOD) values ranging between 0.2 and 0.6 (at 440 nm) over the western and central Mediterranean basins. One important point of this experiment concerns the direct observations of aerosol extinction onboard the ATR-42, using the CAPS system, showing local maxima reaching up to 150 M m−1 within the dust plume. Non-negligible aerosol extinction (about 50 M m−1) has also been observed within the marine boundary layer (MBL). By combining the ATR-42 extinction coefficient observations with absorption and scattering measurements, we performed a complete optical closure revealing excellent agreement with estimated optical properties. This additional information on extinction properties has allowed calculation of the dust single scattering albedo (SSA) with a high level of confidence over the western Mediterranean. Our results show a moderate variability from 0.90 to 1.00 (at 530 nm) for all flights studied compared to that reported in the literature on this optical parameter. Our results underline also a relatively low difference in SSA with values derived near dust sources. In parallel, active remote-sensing observations from the surface and onboard the F-20 aircraft suggest a complex vertical structure of particles and distinct aerosol layers with sea spray and pollution located within the MBL, and mineral dust and/or aged North American smoke particles located above (up to 6–7 km in altitude). Aircraft and balloon-borne observations allow one to investigate the vertical structure of the aerosol size distribution showing particles characterized by a large size (> 10 µm in diameter) within dust plumes. In most of cases, a coarse mode characterized by an effective diameter ranging between 5 and 10 µm, has been detected above the MBL. In terms of shortwave (SW) direct forcing, in situ surface and aircraft observations have been merged and used as inputs in 1-D radiative transfer codes for calculating the aerosol direct radiative forcing (DRF). Results show significant surface SW instantaneous forcing (up to −90 W m−2 at noon). Aircraft observations provide also original estimates of the vertical structure of SW and LW radiative heating revealing significant instantaneous values of about 5° K per day in the solar spectrum (for a solar angle of 30°) within the dust layer. Associated 3-D modeling studies from regional climate (RCM) and chemistry transport (CTM) models indicate a relatively good agreement for simulated AOD compared with observations from the AERONET/PHOTONS network and satellite data, especially for long-range dust transport. Calculations of the 3-D SW (clear-sky) surface DRF indicate an average of about −10 to −20 W m−2 (for the whole period) over the Mediterranean Sea together with maxima (−50 W m−2) over northern Africa. The top of the atmosphere (TOA) DRF is shown to be highly variable within the domain, due to moderate absorbing properties of dust and changes in the surface albedo. Indeed, 3-D simulations indicate negative forcing over the Mediterranean Sea and Europe and positive forcing over northern Africa. Finally, a multi-year simulation, performed for the 2003 to 2009 period and including an ocean–atmosphere (O–A) coupling, underlines the impact of the aerosol direct radiative forcing on the sea surface temperature, O–A fluxes and the hydrological cycle over the Mediterranean
Estimation from Moments Measurements for Amyloid Depolymerisation
International audienceEstimating reaction rates and size distributions of protein polymers is an important step for understanding the mechanisms of protein misfolding and aggregation, a key feature for amyloid diseases. This study aims at {setting} this framework problem when the experimental measurements consist in the time-dynamics of a moment of the population (\emph{i.e.} for instance the total polymerised mass, as in Thioflavine T measurements, or the second moment measured by Static Light Scattering). We propose a general methodology, and we solve the problem theoretically and numerically in the case of a depolymerising system. We then apply our method to experimental data of degrading oligomers, and conclude that smaller aggregates of ovPrP protein should be more stable than larger ones. This has an important biological implication, since it is commonly admitted that small oligomers constitute the most cytotoxic species during prion misfolding process