ACI (Acta Cardiologia Indonesiana)
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Acute Changes on Pulmonary Pressure Following Percutaneous Secundum Atrial Septal Defect Closure
No full textAcute Changes on Pulmonary Pressure Following Percutaneous Secundum Atrial Septal Defect Closur
Correlation between Blood Pressure and Severity of Atherosclerosis in The Left Main Coronary Artery with CT Coronary Angiography Examination
No full textBackground: Cardiovascular disease, especially hypertension, is the main cause of death in both developed and developing countries. Hypertensioncan lead to atherosclerosis, which is the most common cause of ischemic and coronary heart disease. Some countries have used Computed Tomography Coronary Angiography (CTCA), which is a noninvasive test, to observe the anatomy of coronary artery. Nevertheless, invasive angiography isstill the gold standardfor coronary artery visualization. Atherosclerotic plaques cancause left main coronary artery stenosis. Purpose: The purpose of this research is to analyze the correlation between blood pressure and severity of the atherosclerosis in the left main coronary artery. With CTCA examination, the presence of plaque, severity of stenosis and type of plaques were assessed. Methods: The study design was analytic observational with cross sectional design. Data was drawn from medical records. The sample included a total of 29 patients which were suspected of having coronary heart disease and examined with CTCA who meet inclusion and exclusion criteria in Dr. Kariadi Hospital, Semarang, Indonesia. Result: The correlation between systolic blood pressure and left main coronary artery stenosis was obtained by Spearman’s rho r = 0.0429, p-value of with of 0.020 (2-tailed). The correlation between diastolic blood pressure and left main coronary artery stenosis was obtained by Spearman’s rho r = 0.354 with p-value of 0.060(2 -tailed). Some types of plaques were found in left main coronary artery, and systolic blood pressure are significantly different analysed usingAnova (analysis of variance) which probability was significant with p value 0.041. Conclusion: There was a significant correlation between systolic blood pressure and left main coronary artery stenosis. Therewas no correlation between diastolic blood pressure and left main coronary artery stenosis. Furthermore, there was a significant difference between systolic blood pressure and the type of plaques in the left main coronary artery.
Correlation between Small Dense Low Density Lipoprotein Level with Major Adverse Cardiac Event in Acute Coronary Syndrome Patients
No full textBackground: Cardiovascular disease is one of major problems in developed and developing countries. Atherosclerosis process begins with endothelial dysfunction. Lipoprotein is important factor in atherogenesis. Previous study stated that about 50% of cardiovascular events happened in individuals with normal or low LDL, therefore LDL plasma level alone is not enough to identifyindividuals with major adverse cardiac events. Individuals with small dense LDL predominant have 3 times fold to have cardiovascular risk. The goal of this study is to know whether the level of sdLDL has impact on in hospital major adverse cardiac events (MACE) of acute coronary syndrome patients. Methods: This was a cross sectional study, enrolling patients with acute coronary syndrome admitted and hospitalized in ICCU of Dr.Sardjito Hospital since September of 2013 until June 2015. The small dense LDL (sdLDLD) level was measured with previous formula using routine blood lipid component. Major adverse cardiac events (MACE) were determined upon observation during horpitalisation and defi ned as death, reinfarction, cardiogenic shock, acute heart failure, ventricular tachycardia or ventricular fi brillation, prolonged angina pain, and the need for immediate coronary intervention. Results: There were 159 patients with mean age 60.80 ± 9.8 years involved in this study. Onehundred eighteen (118) or 73% of patients were male. The mean of sdLDL level in patients with MACE was 108.34 ± 37.94 g/dl and mean sdLDL level in patients without MACE was 105.54 ± 43.10 g/dl. The level of sdLDL in patients without MACE was lower than patients with MACE (p=0.705). In this study we found the cut- off sdLDL level is ≥ 108.085 for higher sdLDL level and < 108.085 for lower sdLDL level. The higher sdLDL level have the prevalence ratio of 1.25 to develop MACE, however the value was not statistically signifi cant.Conclusion: The sdLDL level did not correlate with MACE in hospitalised patients with acute coronary syndrome.Keywords: small dense LDL, acute coronary syndrome, MAC
The Role of Exercise Training in Cardiometabolic Disorder Patients
No full textCardiometabolic diseases are still major causes of mortality in modern society. Despite advanced .....
From Hypertension to Heart Failure: Role of Novel Beta Blocker
No full textAs one of the risk factors of cardiovascular diseases, particularly coronary heart disease and ....
Dyslipidemia and Atherosclerosis
No full textDyslipidemia and atherosclerosis are met in the concept of atherogenic dyslipidemia that has ....
Why Do We Miss A Congenital Heart Disease? - Pediatricians’ Point Of View
No full textWhy Do We Miss A Congenital Heart Disease? - Pediatricians’ Point Of Vie
Pulmonary Hypertension Associated with HIV Infection on Nine Years Old Child
No full textPulmonary Hypertension Associated with HIV Infection on Nine Years Old Chil
Atrioventricular Node Dysfunction in Adult Patient with Atrial Septal Defect: Focus on Pacemaker Management
No full textAtrioventricular Node Dysfunction in Adult Patient With Atrial Septal Defect: Focus on Pacemaker Managemen