ACI (Acta Cardiologia Indonesiana)
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Infective Endocarditis In A Patient With Ventricular Septal Defect And Patent Ductus Arteriosus
No full textInfective Endocarditis In A Patient With Ventricular Septal Defect And Patent DuctusArteriosu
The Correlation Between Mean Pulmonary Arterial Pressure And NT-proBNP In Adult Patient With Uncorrected Atrial Septal Defect
No full textThe Correlation Between Mean Pulmonary Arterial Pressure And NT-proBNP In AdultPatient With Uncorrected Atrial Septal Defec
Cerebral Abscess in Adult with Atrial Septal Defect and Pulmonary Stenosis
No full textCerebral Abscess in Adult with Atrial Septal Defect and Pulmonary Stenosi
Correlation of Serum Levels of Matrix Metalloproteinase-9 to Acute Heart Failure Event as a Complication af Acute Coronary Syndrome
No full textBackground: Acute heart failure (AHF) after acute coronary syndrome (ACS) is the biggest complication with a poor prognosis in a long term. The infl uence of MMP-9 as proteolytic enzyme that degrades extracellular matrix in remodeling left ventricle was recognized. However, according to researcher’s knowledge, evaluation of the MMP-9 as a predictor of AHF after ACS was never reported. Objective: To fi nd out the serum level of MMP-9 in ACS with AHF higher than that without it, as well as to fi nd out the level of MMP-9 with risk of AHF after ACS. Method: The study used a cross-sectional study. Samples were collected by using a consecutive sampling technique among patients with ACS treated in ICCU of Public Hospital Dr Sardjito Yogyakarta, since June 2008 to August 2010. Questionnaires were used to collect sample raw data. The level of MMP-9was examined a time at admission in ICCU before trombolysis was done. The heart failure had Killip II- IV scores. Factors infl uencing the incidence was analyzed by using multivariate analysis technique. A signifi cance level was at p< 0.05. The relative risk of acute heart failure at a certain level of MMP-9 (from cut-off value) was obtained after it was adjusted. Result: Among 122 subjects, 75 was without AHF and 47 with AHF. Median of the level of MMP-9 in the whole sample of ACS was 1248.55 ng/mL with a minimum of 170.50 ng/mL and maximum of 3058.40 ng/mL. Moreover, the level of MMP-9 in ACS with AHF (1700.81±740.43 ng/mL) was signifi cantly higher than ACS without AHF (1189.55±654.60 ng/mL) with p value = 0.000. Independent risk factor after the multivariate analysis was done indicates the level of MMP-9 above 1444 ng/mL (RR= 4.2) and the location of anterior infarction (RR= 2.9). Conclusion: In patients with ACS treated in ICCU of RSUP Dr Sardjito, the level of MMP-9 with AHF was higher than that without it. If the level of MMP-9 above 1444 ng/mL, the possibility of AHF was 4.2 times.Keywords: acute coronary syndrome, MMP-9, acute heart failure after acute coronary syndrom
Electrical and Mechanical Activity of The Heart
No full textThe regularity and rhythm of contraction of the heart muscles (myocardium) depends on how electrical impulses spreads through the conduction system organized. The process is initiated by electrical stimulation which thencauses depolarization. Depolarization is a series of ion transfer through channels that are specifi c to myocardial cell membrane (sarcolemma). These canals spread across the sarcolemma, which include:the Na+ channels, Ca2+ channels, channelK+, Na+-Ca2+exchanger, Na+-K+-ATPase pump and Ca2+active pump. The infl ux of Na+ ions into cell will start depolarization and then spread through conduction system to the rest of the myocardium
Ventricular Septal Defect Closure with Perforated Patch in Large Ventricular Septal Defect with Severe Pulmonary Hypertension and Non Reactive Oxygen Test
No full textManagement of ventricular septal defect (VSD) with severe pulmonary hypertension (PH) had not been extensively studied and is still challenging. The closure of VSD in patients with high pulmonary vascular resistance (PVR) and severe PH is highly risk procedure. If high PVR and severe PH still persist after closure procedure, the patients have poor prognosis. We reported a 24-year-oldwoman whom was diagnosed with large VSD, bidirectional shunt with L to R dominance, dilatation of left ventricle, and mild to moderate mitral regurgitation, mild tricuspid regurgitation and severe PH. Right heart catheterization showed pre-oxygen test: mean aorta pressure 85 mmHg, mean pulmonary artery pressure 65 mmHg, fl ow ratio 5,4, PVR 2,3 WU and pulmonary vascular resistance index (PVRI) 3,22 WU/m2. The results of post-oxygen test: mean aorta pressure 83 mmHg, mean pulmonary artery pressure 63 mmHg, fl ow Ratio 2,2, PVR 0,3 WU and PVRI 0,42 WU/m2. Patient had been performed VSD closure with perforated patch 3 mm. Three month evaluation by echocardiography showed residual VSD 3 mm, L to R shunt, moderate tricuspid regurgitation and mild PH (TVG 36 mmHg). In Baumgartner criteria of VSD operability, this patient was not operable because the ratio of mean pulmonary and systemic circulation more than 2/3, but in Lopez criteria, patient is operable because PVRI below 6 WU/m2. Patient with high and moderate PH and PVR which is still operable, VSD can be closed partially. Partially VSD closure can be performed by transcatheter procedure after PH decrease and stable.Keyword: VSD closure- perforated patch – PH sever
Association of Sporadic Moderate-Vigorous Physical Activity with Cardiovascular Disease Risk Factors - A Systematic Review
No full textBackground: Physical activity is an important factor controlling chronic diseases such as ....
Chronic Thromboembolic Pulmonary Hypertension – from Diagnosis to Intervention
No full textChronic Thromboembolic Pulmonary Hypertension – from Diagnosis to Interventio
Characteristic and Distribution of Congenital Heart Disease in Outpatient Clinic and Pediatric Ward of dr. Soedono Hospital Madiun 2015
No full textCharacteristic and Distribution of Congenital Heart Disease in Outpatient Clinic andPediatric Ward of dr. Soedono Hospital Madiun 201
Pulmonary Embolism in Patient with Atrial Septal Defect and Deep Vein Thrombotic, The Case Report
No full textPulmonary Embolism in Patient with Atrial Septal Defect and Deep Vein Thrombotic, The Case Repor