IMT School for Advanced Studies Lucca

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    409 research outputs found

    The cartography of dreams: application of computational linguistics to the study of sleep conscious experiences

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    The study of dreams represents a crucial intersection between philosophical, psychological, neuroscientific, and clinical interests. Since dreams are subjective experiences spontaneously generated by the brain when it is partially disconnected from the external environment and thus is let free to operate in an unconstrained manner, their study could reveal specific mental processes that are different from those occurring during wakefulness and might provide crucial insights into brain functioning, both in physiological and pathological conditions. Given the high cost of sleep and dream research in terms of human effort and funding, open science and the building of large- scale datasets and repositories will constitute a key for significant advances in the field. At the same time, the analysis of large datasets will require a methodological shift, from human-based assessments to more automated approaches. For instance, methods based on natural language processing (NLP) could replace manual scales and rating approaches for the assessment of dream content. Such a methodological shift could also have positive consequences concerning the reproducibility and reliability of scientific results. Based on the above premises, we created Somnieve, a multimodal, open-source database collecting dream reports along with demographic information and psychometric, cognitive, and electroencephalographic measures obtained from a representative sample of the healthy Italian adult population. In particular, participants were asked to wear an actigraph and to record a report of their last dream experience each morning upon awakening for 14 days. Moreover, they completed a battery of questionnaires and cognitive tests. The database currently includes 1324 dream reports obtained from 161 healthy adult individuals (66M, 18-65y). Beside presenting and describing the Somnieve database, this Thesis work exploited the database to investigate the individual determinants of physiological dream content and recall frequency. We relied on computational linguistics to test whether it might be possible to implement computational linguistics based tools to automatically and objectively code dream content and verify the existence of generalizable semantic patterns in dream narratives. Moreover, we evaluated the inter- and intra-individual factors affecting dream recall frequency. Present results highlight the potential benefits that large multimodal databases like Somnieve could bring for the field of dream research. It is our hope that this, and similar independent efforts by other laboratories, will contribute to improve reproducibility in dream research and identify the individual determinants of dream content and recall frequency in physiological conditions, as well as quantify their possible pathological alterations

    Algorithmic management and wellbeng at work

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    This thesis explores the relationship between Algorithmic Management (AM) and employee well-being in standard work environments. AM, which refers to the use of algorithms to assume managerial functions traditionally handled by humans, is an emerging phenomenon that promises efficiency and objectivity. However, its impact on well-being is still under heated debate, particularly regarding when and why AM leads to positive or negative well-being outcomes for employees. This research seeks to address this debate by examining AM from different perspectives. Specifically, a multi-paradigmatic approach is employed to study when AM enhances or erodes engagement, autonomy, and overall well-being, as well as why these outcomes occur. Drawing on both positivist and interpretivist approaches, this thesis integrates quantitative and qualitative methods to investigate the mechanisms, boundary conditions, as well as sensemaking processes that shape the AM-well-being relationship. First, in line with a positivist perspective, we use quantitative surveys to explore how AM relates to employee engagement, mediated by social and economic exchanges. The findings of the first study suggest AM shifts work interactions from social to economic, often correlating with lower engagement. A close leader’s moderating role is highlighted, showing that strong interpersonal relationships can buffer these negative effects. The second study addresses job autonomy, revealing that AM’s association with reduced autonomy is influenced by factors like systemic justice and individual proactivity, with high justice and proactivity mitigating the loss the job autonomy. The final study adopts an interpretivist approach, using qualitative methods to explore how employees make sense of and respond to AM in environments marked by uncertainty and complexity. It shows that employees actively reinterpret or resist AM’s influence on their well- being and emphasizes employees’ political potential to reshape workplace dynamics in an AM context. The thesis concludes that AM poses challenges to employee well-being in standard work settings, despite efficiency gains. To balance these aspects, organizations should implement AM systems that prioritize genuine interpersonal relationships, justice, and autonomy. This research provides a nuanced understanding of AM’s dual nature and practical insights for its ethical use at work

    Brexit, Trade Disruptions, and Export Recommendations

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    This doctoral dissertation is structured into three chapters, each ad- dressing aspects related to policy evaluation, with a focus on events car- rying substantial implications for the economy and international trade. These events include the Brexit referendum, trade disruptions, and the development of export recommendations. The Economic Cost of a Referendum. The Case of Brexit. This paper esti- mates how GDP would have behaved in the United Kingdom after the Brexit referendum in the absence of the mentioned poll using the Syn- thetic Control Method. We contribute to the research on the effects of Brexit by quantifying the macroeconomic cost of this referendum before the actual Brexit has taken place. We find a large and significant negative effect of the Brexit referendum on the GDP of UK. This loss is increasing in time representing, in 2017 Q4, 1.71% of the observed GDP of UK. Assessing the Heterogeneous Impact of Economy-Wide Shocks: A Machine Learning Approach Applied to Colombian Firms. This paper investigates the impact of COVID-19 on Colombian exports, revealing a substantial de- cline in survival probabilities during 2020. On average, we find that the COVID-19 shock decreased a firm’s probability of surviving in the export market by about 20 percentage points in April 2020. Importantly, ex- porters more integrated into Global Value Chains (GVCs) and importing higher value emerged as pivotal in bolstering exporter resilience during the crisis, emphasizing the need for policies supporting varied import networks, as well as international trade facilitation. Methodologically, this research innovates by utilizing causal Machine Learning (ML) tools in scenarios where the pervasive nature of the shock hinders the identi- fication of a control group unaffected by the shock, as well as the ex-ante definition of the intensity of the shock’s exposure of each unit, making a traditional control group identification unfeasible. This approach effec- tively predicts firms’ trade and uses these predictions to reconstruct the counterfactual distribution of firms’ trade under different scenarios and to study treatment effect heterogeneity. Exports’ Survival in New Markets: A firm-level export recommendation model. This paper investigates the factors that better predict a firm’s trade status of exporters after expanding to a new destination, specif- ically whether they continue exporting after two years. Using Colom- bian customs data, I show that market-level information is crucial for understanding export survival rates, beyond traditional firm-level char- acteristics like export experience. The paper introduces a novel Machine Learning-based export market entry recommendation tool, designed at the firm-product market level. While firms in the sample did not have access to this tool, the analysis observes which firms chose new destina- tions that align with the recommendations generated by the tool. Sim- ulated back-testing indicates that firms selecting destinations consistent with the tool’s guidance would have experienced a 5 percentage point higher survival rate compared to those choosing other destinations. Ad- ditionally, product growth would have been 34 percentage points higher for products where at least one firm followed the tool’s suggested market entry, compared to those that did not. The findings suggest that incom- plete market insights may lead to sub-optimal export decisions and that exporters incur temporary trade as a way of experimentation and to re- solve incomplete market information

    Circumventing Plague: The Spatial Experience of Women and Men during the Outbreak of 1630-31 Bologna

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    Though managing early modern plague in northern Italy necessitated regulations and restrictions of movement in order to combat outbreaks, the factors resulting in immobility at the same time created opportunities for mobility. The ability to move and interact within the urban environment was contingent on social factors such as age, gender, class and occupational status and remained essential in the shaping of the spatial experience. Moreover, the ability to move across barriers, such as crossing the threshold of the home, formulated possibilities for social life to flourish during plague. This study investigates the relationships between early modern people and places during the period of plague in Bologna from 1630-31 through the lens of the new mobilities paradigm. This model interrogates how places are continuously shaped and reshaped by way of human and non-human interaction. Adopting approaches emerging from the mobility turn, this research places emphasis on the social drivers that contributed to movement and asks: how did mobility inform the various experiences of the plague of 1630-31 in Bologna? Building on the extensive studies on seventeenth-century plague for the cities of Milan, Venice and Florence, this study offers new insights into the early modern experience and approaches to plague from the perspective of the significant northern Italian centre of Bologna. This study draws on a broad array of primary documents including handwritten and printed records, encompassing contemporary chronicles, manuscripts and egal decrees. Historical sources including plague tracts reveal contemporary understanding of combatting plague. Visual sources, such as early modern paintings and architectural plans, alongside digital maps of Bologna’s network of plague hospitals, similarly play a crucial role in uncovering the spatial experience during plague. The research presented in this study contends that the urban experience and the public health management of early modern plague was informed by mobility. Architecture, in combination with regulations and disciplinary punishment, were used to contain, control and limit the movement of people. Despite immobility, men and women found ways to circumvent restrictions. They crossed architectural divides by way of health passes or illicit activities and traversed physical but also social boundaries through professional opportunities. Bolognese citizens continued to move by way of engaging with devotional performances, such as processions. Ritualised performance was enacted to counteract the moral causes of the illness and ultimately served the social life of the community. Mobility was also considered an asset for plague management according to seventeenth-century practice as demonstrated in the creation and employment of a network of plague hospitals in Bologna. Moreover, this study reveals how social dimensions contributed to varying degrees of mobility as women, men, the nobility and the poor each had diverse experiences of plague

    Perception, Cognition and Ayahuasca A Multidimensional Analysis of Alter States of Consciousness

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    My Ph.D. thesis comprises a series of experiments aimed at investigating the impact of a novel ayahuasca analog, pharmahuasca (PHA), on face perception and creative cognition. These studies were executed with a within-subject, double-blind, placebo-controlled design involving 30 healthy male participants. Chapter 2 centers on the effects of psychedelics on face perception, utilizing electroencephalography (EEG) during a visual oddball task with self, familiar, and unknown faces as stimuli. Notable changes induced by PHA in early visual processing, such as increased P1 and reduced N170 across all face categories, were observed. In late visual processing, a decrease in neural activation in response to the self-face, as indicated by the P300 wave, highlights the significance of psychedelics in altering self-referential information processing. Additionally, the impact of psychedelics on face discrimination was explored through a two-alternative forced choice (2-AFC) task, where faces are incrementally morphed to each other, revealing a decreased sensitivity for discrimination during psychedelic experiences across all face categories. Chapter 3 shifts focus to understanding how psychedelics influence creative cognition. Through task-based methodologies, the findings unveil a reduction in convergent thinking without affecting on divergent thinking. Next, we investigate how utilization of different thinking modes during the artistic creation, specifically in the domain of painting, under the influence of psychedelics. Importantly, there was a significant reduction in transitions between different creative thinking modes during the psychedelic-induced creative process, particularly affecting stages traditionally requiring convergent thinking, offered valuable insights into the phenomenological nuances of the interplay between psychedelics and the dynamics of creative thinking

    Phase Field methods for Fracture Mechanics in coupled problems

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    Nowadays, cutting-edge industry processes cannot thrive with- out the integration of multidisciplinary perspectives in all its associated processes. Even the field of Mechanics is not ex- empt from such approaches, since most recent studies now incorporate considerations spanning multiple size scales (multi- scale) and encompassing various branches such as Chemistry, Biology, Electricity, and Magnetism, among others (multi-physics). This is what constitutes the very essence of a coupled prob- lem in Mechanics. The principal objective of this thesis is to specifically explore their impact on structural integrity and reliability in the field of Fracture Mechanics. Consequently, it is necessary to establish a robust mathematical framework to assess the mechanical behavior and failure strength, con- sidering the intricate influence of the multi-scale and multi- physics fields associated with each problem. To accomplish this mission, we have primarily utilized the phase-field ap- proach for fracture, alongside the continuum damage me- chanics technique. Our efforts have been devoted to shed light on representative coupled problems in Fracture Mechanics. To exemplify the breadth of this field, our research comprises a diverse spec- trum of topics. First, the research deals on the problem of hy- drogen embrittlement in polycrystalline materials. Moreover, the residual stress influence on the integrity of soft cylindrical tubes has been investigated. Furthermore, a computational framework for incompressible materials has been proposed. The final topic concerns the application of this last formula- tion in the simulation of swelling of thermoresponsive hydro- gels

    The Problem of Reverse Inference: Philosophical Models and Neuroscientifc Methods

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    Reverse inference is a crucial inferential strategy employed by neuroscientists to infer the engagement of a cognitive pro- cess from observed brain activation in functional magnetic resonance imaging studies. Despite its widespread use, in recent years reverse inference faced increasing skepticism, par- ticularly after Russell Poldrack authoritatively criticized its uncontrolled use in his influential 2006 paper. The general aim of the thesis is to provide an assessment of the current debate about reverse inference at the interface between neuroscience and the philosophy of science, by evaluating the models and methods proposed to improve the theory and practice of reverse inference. To do this, I offer three main contributions to the debate. In the first part of the thesis, I offer a comprehensive and updated overview of the problem of reverse inference in cur- rent cognitive neuroscience, emphasizing both technical and methodological issues. In the second part, I present and discuss the different philo- sophical models of reverse inference proposed in the literature, assessing their relative advantages and limitations. I also dis- cuss two novel models of reverse inference, one based on Bayesian confirmation theory and one based on the idea of inference to the best explanation. In the third part, I present the main results of a systematic review of the literature, aiming at evaluating the impact of NeuroSynth, the most widely employed meta-analytical soft- ware for performing reverse inference, on current practice in neuroscientific research

    Power, Legitimacy, and their Rituals and Imagery: Early Medieval Southern Italy in a cross-cultural Mediterranean Perspective

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    At the end of the X century, in the city of Benevento appeared a liturgical medium that would soon become a peculiarity of the religious life of Southern Italy for the centuries to come: the illustrated scroll, containing the texts of the so-called Exultet prayer and the blessing of the Paschal candle, a ceremony to be held in the Easter Vigil. The liturgy underlining such a ceremony in Southern Italy changed over time, in particular when the original so-called Beneventan liturgy (the traditional rite originating in the city of Benevento after the arrival of the Lombards, as an evolution of the more ancient Ambrosian liturgy) gave way to the imposition of the Franco-Roman one, a result of the spread of the reformist movement that characterized the life of the Church during the XI century. Notwithstanding these changes, the illuminated scroll kept its role and importance, evolving and adapting itself to the new circumstances until at least the XIII century. Religious changes, however, did not come alone: during the whole period from the X to the XII century, Southern Italy as a whole underwent some drastic changes in its political setting. From the second half of the IX century, and precisely from 849, the year of the peace treaty that marked the end of a long civil war, the old duchy of Benevento (a principality since 774, when Arichis II started styling himself as princeps) was divided into two distinct entities: the principality of Benevento, and that of Salerno. Later on, the latter lost its northernmost part, which became an independent county centred around the town of Capua, whose rulers subsequently managed to reunite with Benevento and, under Pandulf Ironhead (943-981) even Salerno, in 978. The (temporary) reunification of the three principalities in one single polity would mark the last moment of unity for the Lombard people before the advent of new political actors, who would radically change the landscape of Southern Italy: the Normans. This is not the place for a detailed narrative of the Norman conquest of Southern Italy, and of the following birth of a unified Regnum under Roger II in 1130. What is important to note here is that the anarchic situation that reigned in continental Southern Italy between the second half of the XI century and the beginning of the XII, and then the birth of a strong monarchy immediately after, both influenced developments in the liturgical sphere and in the organization of the Church. Moreover, Roger II’s new political construction brought under a single rule the four different, often conflicting, cultural worlds that for centuries had interacted with each other in the southern Italian arena: the Lombard, Frankish, Byzantine, and Arab worlds. Alongside the three Lombard principalities, indeed, Southern Italy always saw the presence of lands under Byzantine rule: at the beginning limited, after the first Lombard invasion of the VI century, to the southernmost part of modern day Puglia and to Calabria, the Eastern Roman Empire managed to strengthen its presence and recover some of the lost territories between the IX and X century, and again at the beginning of the XI century, restoring its rule over much Apulia, Lucania, Calabria, and even (briefly) in the very core of the Lombard principalities, Benevento itself.1 On the Tyrrhenian coast, also, a number of cities thrived as political entities nominally still subject to the emperors in Constantinople, but de facto increasingly independent: Naples, Amalfi, Gaeta, among them. A more in-depth look at the political developments that took place in Southern Italy during the period under consideration here will be given in the course of Chapter 2 (and, for what concerns the Byzantine presence, in the Conclusions as well). What is to be said now is that this peculiar political and cultural landscape, as it took its shape from the VIII century onwards, also resulted in the birth of a civilization with characteristics and peculiarities of its own; a civilization that found its expression in the development of an artistic language that ranged from the first exemplars of Lombard ‘royal’ architecture (such as the palatine church of S. Sofia in Benevento, or the reconstruction of Salerno as a new princely capital undertaken by Arichis II), to the most remarkable forms of Romanesque art that developed under the patronage of the first Norman rulers. During all this time, the Exultet rolls stood firmly in their place, were kept in use, and evolved in both iconography and text. As a result, we currently see Exultet rolls spread from Pisa (two at the Museo Diocesano, and one at the archive of the Capitolo metropolitano, dating from the XI to the XIII century), to Velletri, Salerno, Troia, Bari, Gaeta, Paris, London, for a total of twenty-eight scrolls. A rich, though not homogeneous, corpus, with differences in both original composition (some, such as the Exultet from Avezzano, were made without images) and state of preservation. But to consider the scrolls as purely an expression of religion or liturgy would be a mistake: both the chant and its iconography, once this was introduced, contained clear references to the secular authorities in the form of a commemoration, made at the end of the prayer. As a result, starting with the very first scroll in our possession, the Vat. lat. 9820, most of the surviving exemplars show us representations of the ruler (or rulers), representations that changed over time and that represent, by themselves,valuable sources of information about the evolution in the iconography of power in medieval Southern Italy.

    Efficient and Accurate Analysis of Two Classes of Transparent Generative Models

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    While widely used, generative models pose the challenging task of deriving and analyzing their underlying distribution. In this thesis, we focus on two classes of transparent genera- tive models and present new methods to tackle this task. Markov Population Processes use Continuous Time Markov Chains to describe the evolution of populations over time. Their analysis is often hindered by state-space explosion, tack- led with deterministic approximation or truncation techniques. We propose a method, Dynamic Boundary Projection, that couples an exact stochastic description of a subset of states and a deterministic approximation that dynamically shifts the subset across the state space. The resulting finite set of ODEs is asymptotically exact. We show that our method performs well in terms of accuracy and runtimes on challenging sys- tems. We also propose an extension that further reduces the number of equations while maintaining good accuracy. Probabilistic Programs leverage the power of programming languages to define probabilistic models; however, no one- fit-for-all solution exists to derive the posterior distribution. We define a family of approximating semantics, Gaussian Se- mantics, that leverages moment-matching and the approxi- mation power of Gaussian Mixtures to approximate the joint probability distribution over program variables. As the num- ber of the moments matched increases, Gaussian Semantics tends to the exact semantics. We implement an instance of Gaussian Semantics that matches the first two order moments and show that our implementation performs competitively with respect to other state-of-the-art inference methods and excellently on two classes of models taken from the literature

    The Representation of Visual Naturalistic Stimuli in Resting State Activity: An Investigation in the Visual and Motor Areas Representations at Rest

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    Resting state is characterized as an offline period, during which the eyes may be either open or closed. In this disengaged state, one’s system operates independently of external input or feedback, and by definition, relies on an internalized model of the world. Literature shows that resting state activity may reflect the statistics of the natural environment, but also the unique individual biases, and is possible to be reshaped over time. This is highlighted by studies that show that resting state fluctuations maintain traces of everyday activity; but how are these representations extracted, how stable are they, and to what extent are they malleable? To answer that we need to understand: 1) How is our system structured to maintain regularities? 2) How are they integrated in an internalized model? 3) How do low frequencies fluctuate when detecting an error? The main aim of this thesis is to understand how natural information is represented in resting state. The working model is that (1) naturalistic information is processed along a hierarchy in time and space to code higher level information that is low dimensional and sparse (chapter 2). 2) This information is then maintained in resting state in a generic form (chapter 3). 3) This is achieved because low frequency fluctuations are adapted to naturalistic statics, and hence are altered in otherwise unexpected situations (chapter 4). We examined the functional connectivity (FC) of MEG signal changes in the visual (VIS) and dorsal attention (DAN) networks during the observation of naturalistic videos, by comparing them to a pretrained convolutional network. We reveal distinct temporal dynamics in processing low and high-level features. Low-level features are immediately and abundantly represented, while high-level features exhibit a delayed and scarce representation, potentially storing information in a generic form (chapter 2). For instance, we find that the BOLD multivoxel spatial representation of a still hand, controlled for low-level features, is coherent with the spatial representation of the resting somatomotor area, as opposed to another object such as a food item (chapter 3). We suggest that the representations during resting states may contribute to the goal of interacting with the environment. This is enriched by our final findings; the multivoxel spatial representation of observing common movements aligns more coherently with resting somatomotor patterns as opposed to uncommon (chapter 4)

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