30472 research outputs found
Sort by
Reverse engineering of temporal queries mediated by LTL ontologies
In reverse engineering of database queries, we aim to construct a query from a given set of answers and non-answers; it can then be used to explore the data further or as an explanation of the answers and non-answers. We investigate this query-by-example problem for queries formulated in positive fragments of linear temporal logic LTL over time-stamped data, focusing on the design of suitable query languages and the combined and data complexity of deciding whether there exists a query in the given language that separates the given answers from non-answers. We consider both plain LTL queries and those mediated by LTL-ontologies
Humano Virus
Covid-19 wreaked havoc around the world and undoubtedly changed the behavior of many people. Police surveillance over the use of masks, panic in the face of shortages of toilet paper, discussions on the value of life due to the lack of respirators, development of robots to perform human work are some of the topics addressed by Renata Salecl to understand the extent to which human behaviors were disrupted by the global spread of the coronavirus
Women in philosophy
Many philosophical schools included female followers, such as Pythagoreans, Cynics, Cyrenaics, Platonists, Epicureans, and Stoics. The most extensive fragmentary writings by female philosophers are those of Neopythagorean women, particularly Theano, Perictione, Phintys, and Ptolemaïs. The most well-attested women philosophers in antiquity include Aspasia, Diotima, Arete, Hipparchia, Sosipatra, and Hypatia. These women appear to have held many different positions and views. There is no distinct feminine philosophy in antiquity, although some fragments from Pythagorean women are an attempt to apply philosophical principles to the everyday lives of women
Unlocking co-creation for green innovation: an exploration of the diverse contributions of universities
In the context of the green transition, universities have much to offer in joint green innovation projects with business, government and citizens. As hubs of diverse expertise, universities are uniquely placed to build interdisciplinary teams and bridge gaps between society and industry. Their regional ties also enable them to engage with the local ecosystem. This paper draws from ten international case studies of university partnerships with industry and society in green mobility, green energy and green products, services and processes. The comparative evidence gathered from interviews with representatives from these initiatives examines universities’ practices for green co-creation. Additionally, the paper outlines policy recommendations crucial to supporting these initiatives, essential for the global success of sustainable development efforts
'Dem Rauch folgen. Architektur, Totalität und fossiler Kapitalismus'
An adapted version of a chapter from my book Shock City. This was published in German and is included here so an English version is available. It appeared in a collection of essays engaging with German media theory and architecture
Escherichia coli killing by epidemiologically successful sublineages of Shigella sonnei is mediated by colicins.
BACKGROUND: Shigella sp. are enteric pathogens which causes >125 million cases of shigellosis annually. S. sonnei accounts for about a quarter of those cases and is increasingly prevalent in industrialising nations. Being an enteric pathogen, S. sonnei benefits from outcompeting gut commensals such as Escherichia coli to establish itself and cause disease. There are numerous mechanisms that bacterial pathogens use to outcompete its rivals including molecules called colicins. A Type 6 Secretion System (T6SS) was recently described as contributing to E. coli killing in S. sonnei.
METHODS: We used Bulk Phenotyping of Epidemiological Replicates (BPER) which combined bacterial Genome Wide Association Studies (bGWAS) and high throughput phenotyping on a collection of S. sonnei surveillance isolates to identify the genetic features associated with E. coli killing and explore their relationship with epidemiological behaviour. We further explored the presence of colicins and T6SS components in the isolates using genomics, laboratory experimentation, and proteomics.
FINDINGS: Our bGWAS analysis returned known and novel colicin and colicin related genes as significantly associated with E. coli killing. In silico analyses identified key colicin clusters responsible for the killing phenotype associated with epidemiologically successful sub-lineages. The killing phenotype was not associated with the presence of a T6SS. Laboratory analyses confirmed the presence of the key colicin clusters and that killing was contact-independent.
INTERPRETATION: Colicins are responsible for E. coli killing by S. sonnei, not a T6SS. This phenotype contributes to shaping the observed epidemiology of S. sonnei and may contribute to its increasing prevalence globally. BPER is an epidemiologically relevant approach to phenotypic testing that enables the rapid identification of genetic drivers of phenotypic changes, and assessment of their relevance to epidemiology in natural settings.
FUNDING: Biotechnology and Biological Sciences Research Council, Biotechnology and Biological Sciences Research Council Doctoral Training Partnership studentship, Wellcome Trust, Medical Research Council (UK), French National Research Agency
Towards an epistemology of digitally mediated temporality: from ethics to empiricism
The aim of this article is to lay the epistemological groundwork for investigating how the digital present is experienced as present. This is significant because, given the ontological priority of the present in phenomenological inquiry, this gets us closest to capturing digitally mediated experience itself. It will be argued that this does not mean pathologizing the pervasive digitisation of everyday life, and the digital age affords researchers an abundance of resources previously unavailable or elusive. The temporal experience of the unfolding present cannot be made a direct object of conscious cognition, which raises two serious concerns. The first is the possibility that digital actants such as algorithms can intervene in, exploit and modify temporal experience in ways that fly under the radar. The second is the challenge of constructing an epistemology and empiricism up to the task of investigating such phenomena in the pursuit of ethical principles including autonomy and accountability. In theoretical terms the article takes a phenomenological approach in which the present is always ontologically prior to any notion of an origin: in short, we always begin from the experience of finding ourselves thrown into a present – including a presently embodied self – that exceeds our grasp. The experience of temporality is the unfolding of that grasping, of disclosing the world by navigating and acting in it, and that means that understanding it is not a matter of excavating or working backwards to account for how we got to where we are, but mobility from the present
Sources and effects of foreign language enjoyment, anxiety and boredom: a structural equation modelling approach
The present study is among the first to investigate how three foreign language (FL) emotions, namely FL enjoyment (FLE), anxiety (FLCA) and boredom (FLB) are related to each other. It is the first study to consider how the three FL emotions are shaped by one learner-internal variable (attitude toward the FL), by two perceived teacher behaviours (frequency of use of the FL in class and unpredictability) and how all these variables jointly affect leaners’ FL achievement. Participants were 332 FL learners from all over the world studying a wide variety of FLs who filled out an online questionnaire. A close-fitting structural equation model revealed associations between FLE, FLCA, and FLB. Teacher behaviours positively affected FLE, with no discernible effect on FLB or FLCA. Only FLCA was found to have a (negative) effect on academic achievement. The study confirms the complex relationship between teacher behaviours and positive emotions in the FL classroom
The challenges faced during Home Office interview when seeking asylum in the United Kingdom: an Interpretative Phenomenological Analysis
Accounts by those seeking asylum are often challenged by the Home Office (HO) because of apparent inconsistencies and lack of credibility. Yet the ability to disclose everything at initial interview can be impacted by many factors. This study explores how applicants experienced interviews with the HO and its effects. Semi-Structured interviews were conducted with eight participants who had been through the UK asylum process. Transcripts of interviews were analysed using Interpretive Phenomenological Analysis (IPA). Four Superordinate themes were identified; “Confronted by a Hostile System”, “Intra and Interpersonal Barriers at Interview”, “Moments of Reprieve”, “A Destructive Process”. Participants identified experiences of a system that felt overtly and intentionally hostile. Psychological, practical and institutional factors were identified as affecting what they were able to disclose. Participants identified deterioration to their mental health because of the experience, which for some was not alleviated once leave to remain was granted